摘要/Abstract

无论是在实验室还是工业生产中，通过胺的选择性氧化制备亚胺类化合物都具有重要的意义.秉承原子经济性、环境友好的理念，以蝴蝶型络合物Cu₂（ophen）₂为催化剂，实现了需氧型的胺的选择性氧化.值得注意的是，该催化体系对醇与胺的氧化交叉偶联、一级胺的氧化偶联和二级胺的氧化脱氢反应都是有效的.反应产率高达93%，亚胺的选择性高达99%.在反应体系中，避免了昂贵的氮氧自由基类化合物的使用，使得该体系更具有潜在的实际应用价值.
关键词: 需氧氧化, 双核铜配合物, 无碱, 无氮-氧自由基, 高选择性
The selective catalytic oxidation of amines for the synthesis of imines is important both in laboratory and industrial production. From atom-efficient, economic and environmental view of points, dioxygen selective oxidation of amines was achieved by using wings-opened butterfly-like complex Cu₂(ophen)₂ as catalyst. It was worth noting that the catalytic system was efficient to the cross-coupling of alcohols with amines, homocoupling of primary amines and oxidative dehydrogenation of secondary amines. The yield is up to 93% and the selectivity of imines is as high as 99%. Avoiding the use of expensive nitroxyl derivatives and base was suitable for practical application.
Key words: aerobic oxidation, dinuclear Cu-complex, base-free, N-O radical free, high selectivity


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