xm:郭跃伟
xb:男
zc:研究员
xl:博士
dh:+86-
cz:
dzyj:ywguo@simm.ac.cn
grzy:
zjlb:研究员；****；新药；
zw:研究组长、博士生导师
txdz:上海市浦东新区张江高科技园区祖冲之路555号
grjj: 郭跃伟，1997年获意大利国家博士学位，1997-2000年在意科院（CNR）生物活性分子化学所（ICB）及日本北海道大学药学院从事3年博士后研究。2000年到目前在中科院上海药物所任课题组长、研究员（2级）。
yjfx:1.海洋生物和药用植物中生物活性成分的化学研究
2.海洋后鳃亚纲软体生物及其食源生物的化学及化学生态学研究
3.基于功能导向的活性天然产物合成和结构改造
dblz:代表论著(IF>4.7)：1.Z.-F. Zhou, M. Menna, Y.-S. Cai, Y.-W. Guo*, Polyacetylenes of Marine Origin: Chemistry and Bioactivity, Chem. Rev., 2015, 115, 1543-1596. IF=54.32.C.-S. Jiang, W. Mueller, C. Schroder, Y.-W. Guo*, Disulfide- and multisulfide-containing metabolites from marine organisms, Chem. Rev., 2012, 112, 2179-2207. IF=54.33.Y.-S. Cai, Y.-W. Guo*, K. Khron, Structure, bioactivities, biosynthetic relationships and chemical synthesis of the spirodioxynaphthalenes, Nat. Prod. Rep., 2010, 27, 1840-1870. IF=11.84.G. Li, J. S. Dickschat and Y.-W. Guo*, Diving into the world of marine 2,11-cyclized cembranoids: a summary of new compounds and their biological activities, Nat. Prod. Rep., 2020, DOI: 10.1039/d0np00016g. IF=11.85.W. Zhang, Y.-W. Guo*, Y.-C. Gu, Secondary metabolites from South China Sea Invertebretes: chemistry and biological activity, Curr. Med. Chem., 2006, 13, 2041-2090. IF=3.896.C.-L. Gao, G.-G. Hou, J. L., T. Ru, Y.-Z. Xu, S.-Y. Zhao, H.Ye, L.-Y. Zhang, K.-X. Chen, Y.-W. Guo*, T. Pang*, X.-W. Li*, Synthesis and Target Identification of Benzoxepane Derivatives as Potential Anti-neuroinflammatory Agents for Ischemic Stroke, Angew. Chem. Int. Ed. 2019, DOI: 10.1002/anie.. IF=12.257.Q.-H. Wu, S.-W. Li, H. Xu, H. Wang, P. Hu, H. Zhang, C. Luo, K.-X. Chen, B. Nay*, Y.-W. Guo* and X.-W. Li*, Complex polypropionates from a South China Sea photosynthetic mollusk: isolation and biomimetic synthesis highlighting novel rearrangements, Angew. Chem. Int. Ed. 2020, DOI: org/10.1002/ange.. IF=12.258.S.-W. Li, C. Cuadrado, L.-G. Yao, A. H. Daranas*, and Y.-W. Guo*, Quantum Mechanical-NMR-Aided configuration and conformation of two unreported macrocycles isolated from the soft coral Lobophytum sp.: energy calculations versus coupling constants, Org. Lett., 2020, 22, 4093-4096. IF=6.559.Q.-H. Wu, F. Ye, X.-L. Li, L.-F. Liang, J.-D. Sun, H. Sun, Y.-W. Guo*, H. Wang, Uncommon polyoxygenated sesquiterpenoids from South China Sea soft coral Lemnalia flava, J. Org. Chem., 2019, 84, 3083-3092. IF=4.7510.M. Yang, X.-L. Li, J.-R. Wang, X.-X. Lei, W. Tang, X.-W. Li, H. Sun, Y.-W. Guo*, Sarcomililate A, an unusual diterpenoid with tricyclo[11.3.0.02,16]hexadecane carbon skeleton, and its potential biogenetic precursors from the Hainan soft coral Sarcophyton mililatensis, J. Org. Chem., 2019, 84, 2568-2576. IF=4.7511.G. Li, H. Li, Q. Zhang, M. Yang, Y.-C. Gu, L.-F. Liang, W. Tang, Y.-W. Guo*, Rare cembranoids from Chinese soft coral Sarcophyton ehrenbergi: structural and stereochemical studies, J. Org. Chem. 2019, 84, 5091-5098. IF=4.7512.F. Ye, J. Li, Y. Wu, Z.-D. Zhu, E. Mollo, M. Gavagnin, Y.-C. Gu, W.-L. Zhu, X.-W. Li, Y.-W. Guo*, Sarinfacetamides A and B, nitrogenous diterpenoids with tricyclo[6.3.1.01,5]dodecane scaffold from the South China Sea soft coral Sarcophyton infundibuliforme, Org. Lett., 2018, 20, 2637-2640. IF=6.5513.J. Liu, H. Li, K.-X. Chen, J.-P. Zuo, Y.-W. Guo*, W. Tang, X.-W. Li, Design and synthesis of marine phidianidine derivatives as potential immunosuppressive agents, J. Med. Chem., 2018, 61, 11298-11308. IF=6.0514.D.-Y. Sun, G.-Y. Han, N.-N. Yang, L.-F. Lan, X.-L. Li, Y.-W. Guo*, Racemic trinorsesquiterpenoids from the Beihai sponge Spongia officinalis: structure and biomimetic total synthesis, Org. Chem. Front., 2018, 5,1022-1027. IF=5.0715.D.-Y. Sun, G.-Y. Han, J.-X. Gong, B. Nay, X.-L. Li, Y.-W. Guo*, Asymmetric total synthesis of distaminolyne A and revision of its absolute configuration, Org. Lett., 2017, 19, 714-717. IF=6.5516.F. Ye, Z.-D. Zhu, J.-S. Chen, J. Li, Y.-C. Gu, W.-L. Zhu, X.-W. Li, Y.-W. Guo*, Xishacorenes A-C, diterpenes with bicyclo[3.3.1]nonane nucleus from the Xisha soft coral Sinularia polydactyla, Org. Lett., 2017, 19, 4183-4186. IF=6.5517.J. Chen, J.-J. Li, J.-Z. Wang, H. Li, W. Wang, Y.-W. Guo*, Phosphine catalyzed aza-MBH reactions of vinylpyridines: efficient and rapid access to 2,3,5-triarylsubstituted 3-pyrrolines, Org. Lett., 2015, 17, 2214-2217. IF=6.5518.Z.-F. Zhou, T. Kurtan, X.-H. Yang, A. Mandi, B.-P. Ye, O. Taglialatela-Scafati, Y.-W. Guo*, Penibruguieramine A, a novel pyrrolizidine alkaloid from the endophytic fungus Penicillium sp. GD6, associated with the Chinese mangrove Bruguiera gymnorrhiza, Org. Lett., 2014, 15, 1390-1393. IF=6.5519.L.-F. Liang, T. Kurtán, A. Mándi, L.-G. Yao, J. Li, W. Zhang, Y.-W. Guo*, Unprecedented diterpenoids as a PTP1B inhibitor from Hainan soft coral Sarcophyton trocheliophorum Marenzeller, Org. Lett., 2013, 15, 274-277. IF=6.5520.R. Jia, X.-H. Yan, W. Zhang, Y.-W. Guo*, Bislatumlides C-F, further biscembranes from the Hainan soft coral Sarcophyton latum, J. Org. Chem., 2013, 78, 3113-3119. IF=4.7521.X.-L. Chen, H.-L. Liu, J. Li, G.-R. Xin, Y.-W. Guo*, Paracaseolide A, first a--alkylbutenolide dimer with an unusual tetraquinane oxa-cage bislactones skeleton from Chinese mangrove Sonneratia paracaseolaris, Org. Lett.,, 2011, 13, 5032-5035. IF=6.5522.M. Carbone, Y. Li, C. Irace, E. Mollo, F. Castelloccio, A. Di Pascale, G. Cimino, R. Santamaria, Y.-W. Guo* and M. Gavagnin*, Structure and cytotoxicity of phidianidines A and B: first finding of 1,2,4-oxadizole system in a marine natural product, Org. Lett., 2011, 13, 2516-2519. IF=6.5523.Y.-S. Cai, T. Kurtán, Z.-H. Miao, A. Mándi, I. Komáromi, H.-L. Liu, J. Ding, Y.-W. Guo*, Palmarumycins BG1–BG7 and preussomerin BG1, and establishment of their absolute con?gurations using theoretical calculations of electronic circular dichroism spectra, J. Org. Chem., 2011, 76, 1821-1828. IF=4.7524.E. Manzo, M. Carbone, E. Mollo, C. Irace, A. Di Pascale, Y. Li, L. Ciavatta, G. Cimino, Y.-W. Guo* and M. Gavagnin*, Structure and synthesis of a unique isonitrile lipid isolated from the marine mollusk Actinocyclus papillatus. Org. Lett., 2011, 13, 1897-1899. IF=6.5525.W. Zhang, Y.-W. Guo*, K. Krohn, Macropodumines A-C, Novel pentacyclic alkaloids with an unusual skeleton or zwitterion moiety from Daphniphyllum macropodum Miq., Chem. a Euro. J., 2006, 12, 5122-5127. IF=5.1626.J.-X. Gong, X. Shen*, L.-G. Yao, H.-L. Jiang*, K. Krohn, Y.-W. Guo*, Total synthesis of gymnorrhizol, an unprecedented 15-membered macrocyclic polydisulfide from the Chinese mangrove Bruguiera Gymnorrhiza, Org. Lett., 2007, 9, 1715-1716. IF=6.5527.Z.-Y. Li, P. Chen, H.-G. Xu, Y.-M. Yang, S.-Y. Peng, Z.-Z. Zhao, Y.-W. Guo*, Macropodumines D and E, two new alkaloids with unusual skeletons from Daphniphyllum macropodum Miq., Org. Lett., 2007, 9, 477-480. IF=6.55
jyjl:北京中医药大学中药学院，学士
删除或更新信息，请邮件至freekaoyan#163.com(#换成@)
