xm:谭昌恒
xb:男
zc:研究员
xl:博士
dh:+86-
cz:86-
dzyj:chtan@simm.ac.cn
grzy:
zjlb:研究员
zw:研究组长
txdz:上海市浦东新区祖冲之路555号
grjj:谭昌恒，2001年毕业于中科院上海药物研究所，获博士学位，现为中科院上海药物研究所天然药物研究室研究员，研究组长，上海市药学会中药专业委员会委员，主要从事中草药、民间药和其他天然产物的结构新颖和具有生物活性的化合物的发现以及在此基础上的新药开发研究。已完成100余种药用植物的化学成分研究，主持完成国家科技重大专项、“863”计划、“十一五”国家科技支撑计划、国家自然科学基金和上海市科委等多个项目的研究。已培养博士后1人，博士5人，硕士19人，在SCI期刊发表学术论文92篇，合作编写专著3部，申请中国发明专利和PCT专利17项，已授权7项。
yjfx:1.药用天然产物的活性物质基础研究；
2.功能性天然产物的生理活性物质及提取工艺的应用研究；
3.中成药的活性化合物、质量控制和作用机制研究；
4.活性天然化合物的构效关系和结构优化研究；
5.基于活性天然化合物及其结构优化物的创新药物研发。
dblz:1.X.-F. Wang, Z. Zhu, T.-T. Hao, Q.-Q. Fang, K. Jiang, S.-J. Qu, J.-P. Zuo, W. Zhu, S.-J. He*, C.-H. Tan*, Alopecines A – E, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides. Bioorg. Chem., 2020, 99, 103812.2.Q.-Q. Wang, X.-D. Wang, L.-Z. Wu, Q.-Q. Fang, Y.-N. Liu, K. Jiang, S.-J. Qu*, C.-H. Tan*, Polyprenylated acylphloroglucinols as deubiquitinating protease USP7 inhibitors from Hypericum hookerianum, Fitoterapia, 2020, 146, 104678.3.R.-Y. Pan, J. Ma, X.-X. Kong, X.-F. Wang, S.-S. Li, X.-L. Qi, Y.-H. Yan, J.-B. Cheng, Q.-S. Liu, W.-Z. Jin, C.-H. Tan, Z.-Q. Yuan*, Sodium rutin ameliorates Alzheimer’s disease-like pathology by enhancing microglial amyloid-？ clearance. Sci. Adv., 2019; 5, eaau6328.4.X.-F. Wang, F.-F. Liu, Z.-D. Zhu, Q.-Q. Fang, S.-J. Qu, W.-L. Zhu, L. Yang*, J.-P. Zuo, C.-H. Tan*, Flueggenoids A – E, new dinorditerpenoids from Flueggea virosa. Fitoterapia, 2019, 133, 96-101.5.D.-D. Dong, H. Li, K. Jiang, S.-J. Qu, W. Tang, C.-H. Tan*, Y.-M. Li*, Diverse lignans with anti-inflammatory activity from Urceola rosea. Fitoterapia, 2019, 134, 96-100.6.Y.-Q. Ma, M.-H. Liu, T. Tan, A.-P. Yan, L. Guo, K. Jiang, C.-H. Tan*, Y.-Q. Wan*, Deep eutectic solvents used as extraction solvent for the determination of flavonoids from Camellia oleifera flowers by high-performance liquid chromatography. Phytochem. Anal., 2018, 29(6), 639-648.7.W.-P. Wang, K. Jiang, P. Zhang, K.-K. Shen, S.-J. Qu, X.-P. Yu, C.-H. Tan*, Highly oxygenated and structurally diverse diterpenoids from Euphorbia helioscopia. Phytochemistry, 2018, 145, 93–102.8.Z.-L. Liu, H.-R. Zhu, S.-J. Qu, L.-S. Tang, L.-H. Cao, W.-B. Yu, X.-M. Yang, S.-M. Jiang, D.-Y. Zhu, C.-H. Tan*, L. Yu*, Pyramidatine (Z88) sensitizes vincristine-resistant human oral cancer (KB/VCR) cells to chemotherapeutic agents by inhibition of P-glycoprotein. Anticancer Agents Med. Chem., 2018, 18(2), 286-294.9.Y.-M. Zhai, K. Jiang, S.-J. Qu, H.-F. Luo, J.-J. Tan, C.-H. Tan*, Structurally diverse stilbene dimers from Gnetum montanum Markgr: studies on the 1H chemical shift differences between dimeric stilbene epimers correlating to the relative configurations. RSC Adv., 2016, 6, 50083–50090.10.D.-Y. Zhu, C.-H. Tan, Y.-M. Li. (Ch.4) The overview of studies on huperzine A: a natural drug for the treatment of Alzheimer\'s disease. Eds.: Liang, X.-T., Fang, W.-S.. Medicinal Chemistry of Bioactive Natural Products (2006):143-182.
jyjl:南昌大学化学系，理学士
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