xm:赵维民
xb:男
zc:研究员
xl:博士
dh:
cz:
dzyj:wmzhao@simm.ac.cn
grzy:
zjlb:研究员
zw:中科院上海药物所研究员、博士生导师、研究组长
txdz:上海市浦东张江祖冲之路555号
grjj:赵维民博士多年致力于天然药物药效物质基础的发现研究，以期为天然药物的质量控制和新型天然药物制剂的研发提供科学依据。所发现的具有免疫调节活性的杠柳苷类化合物正在进行治疗类风湿性关节炎新药临床前研究。现承担科技部“重大新药创制”科技重大专项和国家自然科学基金等科研项目。迄今已发表研究论文一百余篇，专利授权十余项。主持翻译《制备色谱技术——在天然产物分离中的应用》和《生物活性天然产物分离策略手册》，作为主编和副主编参与编写《天然产物活性成分分离》和《天然产物化学》（第二版）等书籍。
yjfx:1.天然药物活性作用物质基础的发现研究；
2.活性天然产物结构类似物的合成与新药先导化合物的发现研究。
dblz:1.Fu YF, Wang W, Gong Q, Zhang HY, Zhao WM. Neuroprotective Dihydro-β-agarofuran-Type Sesquiterpenes from the Seeds of Euonymus maackii. J. Nat. Prod. 2019, 82, 3096-3103.2.Fu YF, Zhao WM. Polyesterified Sesquiterpenoids from the Seeds of Celastrus paniculatus as Lifespan-Extending Agents for the Nematode Caenorhabditis elegans. J. Nat. Prod. 2020, 83, 505-515.3.Fu YF, Ding XY, Zhang XL, Shao XC, Zhao JH, Xu YC, Luo XM, Zhao WM. Diterpenoids from the Root Bark of Pinus massoniana and Evaluation of Their Phosphodiesterase Type 4D Inhibitory Activity. J. Nat. Prod. 2020, 83, 1229-1237.4.Wang LY, Qin JJ, Chen ZH, Zhou Y, Tang W, Zuo JP, Zhao WM. Absolute Configuration of Periplosides C and F and Isolation of Minor Spiro-orthoester Group-Containing Pregnane-type Steroidal Glycosides from Periploca sepium and Their T-Lymphocyte Proliferation Inhibitory Activities. J. Nat. Prod. 2017, 80, 1102-1109.5.Li JL, Gao ZB, Zhao WM. Identification and Evaluation of Antiepileptic Activity of C-21 Steroidal Glycosides from the Roots of Cynanchum wilfordii. J. Nat. Prod. 2016, 79, 89-97.6.Gao L, Zhang RJ, Lan JF, Ning RN, Wu D, Chen D, Zhao WM. β-Dihydroagarofuran-Type Sesquiterpenes from the Seeds of Celastrus monospermus and Their Lifespan-Extending Effects on the Nematode Caenorhabditis elegans. J. Nat. Prod. 2016, 79, 3039-3046.7.Li JL, Zhou J, Chen ZH, Guo SY, Li CQ, Zhao WM. Bioactive C-21 Steroidal Glycosides from the Roots of Cynanchum otophyllum That Suppress the Seizure-like Locomotor Activity of Zebrafish Caused by Pentylenetetrazole. J. Nat. Prod. 2015, 78, 1548-1555.8.Ning RN, Lei Y, Liu SZ, Wang HM, Zhang RJ, Wang W, Zhu YD, Zhang HY, Zhao WM. Natural β-Dihydroagarofuran-Type Sesquiterpenoids as Cognition-Enhancing and Neuroprotective Agents from Medicinal Plants of the Genus Celastrus. J. Nat. Prod. 2015, 78, 2175-2186.
jyjl:北京医科大学药学院药物化学专业，获学士学位
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