张国强
职称：副研究员、硕士研究生导师
学历/学位：研究生/理学博士
电话：
电子邮箱：gqzhang@jiangnan.edu.cn


简介
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从事生物催化与合成生物学方面研究和教学工作，主要方向为工业酶分子改造与高效蛋白表达系统开发。近年来，在ACS Catal, ACS Synth Biol, J Biol Chem, Trends Food Sci Tech等领域主流杂志发表论文十余篇；申请国际与国内发明专利6项，授权1项；目前主持省部级与企业合作科研项目4项；现为Microb Cell Fact, Appl Microbiol Biotechol, Sci Rep-UK等期刊杂志审稿人。



学习工作经历
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2004-2008 山东大学，生物技术，理学学士
2008-2011 河南农业大学，微生物学，理学硕士
2011-2015 中科院天津工业生物技术研究所，生化与分子生物学，理学博士
2015-2018 美国明尼苏达大学，博士后，生物催化与合成生物学
2019-至今 江南大学粮食发酵工艺与技术国家工程实验室，副研究员



主要成果
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一、论文（论著）发表情况
1. Zhang G, Quin MB*, Schmidt-Dannert C*. (2018) Self-assembling protein scaffold system for easy in vitro co-immobilization of biocatalytic cascade enzymes. ACS Catal. 8:5611-5620.
2. Zhang G, Johnston T, Quin MB*, Schmidt-Dannert C*. (2019) Developing a protein scaffolding system for rapid enzyme immobilization and optimization of enzyme functions for biocatalysis. ACS Synth Biol. 8(8):1867-1876
3. Zhang G, Schmidt-Dannert S, Quin MB*, Schmidt-Dannert C*. (2019) Protein-based scaffolds for enzyme immobilization. Methods Enzymol. 617:323-362.
4. Zhang G, Lin Y, Qi X, Li L, Wang Q*, Ma Y. (2015) TALENs assisted multiplex editing for accelerated genome evolution in Saccharomyces cerevisiae. ACS Synth Biol. 4(10):1101-1111.
5. Zhang G, Lin Y, Qi X, He P, Wang L, Wang Q*, Ma Y. (2015) Genome shuffling of non-conventional yeast Pichia anomala for improved sugar alcohol production. Microb Cell Fact. 14:112.
6. Zhang G, Lin Y, He P, Li L, Wang Q*, Ma Y. (2014) Characterization of the sugar alcohol-producing yeast Pichia anomala. J Ind Microbiol Biotechnol. 41(1):41-48.
7. Zhang G, Wang Q*. (2017) Development, characterization and biomanufacturing of sugar alcohols: Functional Carbohydrates, pp269-290, CRC Press, Boca Raton, FL. ISBN: 76.
8. Zhang G, Zhao X, Li X, Du G, Zhou J, Chen J*. (2020) Challenges and possibilities for bio-manufacturing cultured meat. Trends Food Sci Tech. 97:443-450
9. Zhang G, Chen Y, Du G*. (2020) Advances in Enzyme Catalysis and Technologies: Biomass, Biofuels, Biochemicals, Elsevier, Amsterdam, Netherlands. ISBN: 09
10. Zhang G, Zhao X, Li X, Sun X, Zhou J, Du G, Chen J*. (2019) Application of cell culture techniques in cultured meat-a review. Chin J Biotechnol. 35(8):1374-1381.
11. Zhang S, Zhou J, Zhang G*, Chen J*. (2020) Construction and optimization of p-coumaric acid-producing Saccharomyces cerevisiae. Chin J Biotechnol. Accepted
12. Schmidt-Dannert S, Zhang G, Johnston T, Quin MB* and Schmidt-Dannert C*. (2018) Building a toolbox of protein scaffolds for future immobilization of biocatalysts. Appl Microbiol Biotechol. 102(19):8373-8388.
13. Liu L*, Zhang G, Zhang Z, Wang S, Chen H. (2012) Terminal amino acids disturb xylanase thermostability and activity. J Biol Chem. 286(52):44710-44715.
14. Li L, Zhang G, Wang Q*. (2016) De novo transcriptomic analysis of Chlorella sorokiniana reveals differential genes expression in photosynthetic carbon fixation and lipid production. BMC Microbiol. 16(1):223.
15. Li X, Zhang G, Zhao X, Zhou J, Du G, Chen J*. (2019) A conceptual air-lift reactor design for large scale animal cell cultivation in the context of in vitro meat production. Chem Eng Sci. 211: 115269
16. Quin MB, Wallin K, Zhang G, Schmidt-Dannert C*. (2017) Spatial organization of multi-enzyme biocatalytic cascades. Org Biomol Chem 15(20):4260-4271.
二、专利情况
1. 王钦宏，张国强，贺鹏。一种新型产糖醇酵母菌株基因组重排技术的构建及其应用，专利授权号：ZL2.9，2019-04-30
2. Schmidt-Dannert C, Quin MB, Zhang G, Wallin K. Self-assembling protein scaffolds and methods. PCT/US2018/043491
3. 张国强，陈坚，周景文，堵国成，赵鑫锐，李雪良。一种无血清培养体系及其在细胞培养肉中的应用，专利申请号：6.6
4. 张国强，陈坚，周景文，堵国成，赵鑫锐，李雪良。一种低致敏性植物蛋白肉的制备方法，专利申请号：1.7
三、承担教学科研项目情况
1. 微生物化学品工厂的途径创建及应用，国家重点研发计划项目子课题
2. 体内连续定向进化对α-淀粉酶耐酸性改造的研究，江苏省自然科学青年基金
3. 生物酶法与理化加工协同改良植物蛋白，天津市合成生物技术创新提升项目
4. 大肠杆菌体内连续定向进化系统开发，江南大学自主科研计划
5. 产酸性α-淀粉酶菌株进化改造与高通量筛选，企业合作项目
四、获奖情况（含指导学生获奖）

以上资料更新时间截止：2020年4月