Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 邓亮生教授 (化学病理学系) |
| 胡令芳教授 (内科及药物治疗学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1017/S0959259809990451 |
引用次数
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/3Scopus source URL
其它资讯
摘要Telomere length is a reflection of cumulative oxidative and inflammatory stress throughout the life course, as well as oestrogen exposure. There is evidence that telomere length is associated with lifespan; however, it does not appear to be a better indicator of biological age than chronological age, even though it can be considered a biomarker of ageing. There are studies showing association between leukocyte telomere length and many of the common diseases of ageing, lifestyle factors and socioeconomic status. However, the associations are less marked among older people. Research in the area of manipulation of genetic control of telomerase activity controlling telomere length may have clinical applications in future. Copyright ? 2010 Cambridge University Press.
着者Woo J., Suen E., Tang N.L.S.
期刊名称Reviews in Clinical Gerontology
详细描述doi: 10.1017/S0959259809990451.
出版年份2010
月份2
日期1
卷号20
期次1
出版社Cambridge University Press
出版地United Kingdom
页次1 - 9
国际标準期刊号0959-2598
语言英式英语
关键词ageing, chronic disease, frailty, lifespan, telomeres
