Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 胡令芳教授 (内科及药物治疗学系) |
| 邓亮生教授 (化学病理学系) |
| 梁志信先生 (香港中文大学赛马会骨质疏鬆预防及治疗中心) |
| 郭志锐教授 (内科及药物治疗学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1038/jhh.2008.156 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/22WOS source URL
其它资讯
摘要Both hypertension and osteoporosis have common underlying nutritional aetiology, with regards to dietary cations intake. We tested the hypothesis that sodium intake reflected in urinary Na/Cr and blood pressure would be negatively associated with bone mineral density (BMD), whereas other cations may have opposite associations. Subjects were part of a study of bone health in 4000 men and women aged 65 years and over. A total of 1098 subjects who were not on antihypertensive drugs or calcium supplements and who provided urine samples were available for analysis. Logistic regression was used to examine associations between total hip and lumbar spine BMD, age, gender, body mass index (BMI), urinary Na/Cr, K/Cr, calcium and magnesium intake, systolic blood pressure and diastolic blood pressure. Total hip BMD was inversely associated with age, being female and urinary Na/Cr, and positively associated with BMI, urine K/Cr and dietary calcium intake. Lumbar spine BMD was inversely associated with being female and urinary Na/Cr, and positively associated with BMI, dietary calcium intake and SBP. We conclude that sodium intake, reflected by urinary Na/Cr, is the major factor linking blood pressure and osteoporosis as shown by the inverse relationship with BMD. The findings lend further emphasis to the health benefits of salt reduction in our population both in terms of hypertension and osteoporosis. Journal of Human Hypertension (2009) 23, 451-455; doi:10.1038/jhh.2008.156; published online 18 December 2008
着者Woo J, Kwok T, Leung J, Tang N
期刊名称JOURNAL OF HUMAN HYPERTENSION
详细描述doi:10.1038/jhh.2008.156.
出版年份2009
月份7
日期1
卷号23
期次7
出版社NATURE PUBLISHING GROUP
页次451 - 455
国际标準期刊号0950-9240
语言英式英语
关键词blood pressure; calcium; magnesium; osteoporosis; potassium; sodium
Web of Science 学科类别Cardiovascular System & Cardiology; Peripheral Vascular Disease; PERIPHERAL VASCULAR DISEASE
