Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 韦妙宜教授 (那打素护理学院) |
| 林伟基教授 (化学病理学系) |
| 邓亮生教授 (化学病理学系) |
| 黄永坚教授 (儿科学系) |
| 伍楚贤教授 (内科及药物治疗学系) |
| 施庆仪博士 (儿科学系) |
| 梁廷勋教授 (儿科学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1111/j.1398-9995.2008.01873.x |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/77WOS source URL
其它资讯
摘要Single-nucleotide polymorphism (SNP)-based genome-wide association study revealed that markers on chromosome 17q21 were linked to childhood asthma but not atopy in Caucasians, with the strongest signal being detected for the SNP rs7216389 in the ORMDL3 gene. Such association was unknown in Chinese. This study delineated the allele and genotype frequencies of 10 SNPs at chromosome 17q21, and investigated the relationship between these SNPs and asthma and plasma IgE in southern Chinese children.
着者Leung TF, Sy HY, Ng MCY, Chan IHS, Wong GWK, Tang NLS, Waye MMY, Lam CWK
期刊名称Allergy,Allergy
出版年份2009
月份4
日期1
卷号64
期次4
出版社WILEY-BLACKWELL PUBLISHING, INC
页次621 - 628
国际标準期刊号0105-4538
电子国际标準期刊号1398-9995
语言英式英语
关键词asthma; children; Chinese; genome-wide association; single-nucleotide polymorphism
Web of Science 学科类别Allergy; ALLERGY; Immunology; IMMUNOLOGY
