姓名
孙红宾


职称
研究员

学科/专业学位类别
食品科学与工程/轻工技术与工程

研究方向
结构生物学

1.导师基本情况
孙红宾，博士，研究员，硕士生导师。2007年毕业于中国科学技术大学生命科学学院生物化学与分子生物学专业，获博士学位；2007年至2009年在美国德州大学西南医学中心药学系从事博士后研究工作；2009年至2018年，在中科院强磁场科学中心工作，先后担任副研究员、研究员，硕士生导师。中科院青年创新促进会会员。2018年作为优秀青年拔尖人才引进到郑州轻工业大学工作。
主要研究方向为应用核磁共振研究微生物相关蛋白质的结构与功能，抗菌肽的抗菌机制。
2.代表性成果
1.Jiarong Wang, Kun Ma, Maosen Ruan, Yujuan Wang, Yan Li, Yu V. Fu, Yonghong Song, Hongbin Sun# and Junfeng Wang#. A novel cecropin B-derived peptide with antibacterial and potential anti-inflammatory properties. PeerJ. 2018 Jul 25;6:e5369. (#co-corresponding author)
2.Shanhui Liao, Hongbin Sun#, Chao Xu#. YTH Domain: A Family of N6-methyladenosine (m6A) Readers. Genomics Proteomics Bioinformatics. (2018) 16(2):99-107 (#co-corresponding author)
3.Yue Yuan*,Hongbin Sun*, Shuchao Ge*, Mengjing Wang, Hongxin Zhao, Lin Wang, Linna An,Jia Zhang,Huafeng Zhang, Bing Hu, Junfeng Wang, and Gaolin Liang. Controlled Intracellular Self-Assembly and Disassembly of 19F Nanoparticles for MR Imaging of Caspase 3/7 in Zebrafish. ACS Nano. (2015) 27:761-8. (*co-first author)
4.Jiarong Wang, Yan Li, Xiaoming Wang, Wei Chen, Hongbin Sun#, Junfeng Wang#. Lipopolysaccharide induces amyloid formation of antimicrobial peptide HAL-2. Biochim Biophys Acta. 2014 Nov;1838(11):2910-8. (#co-corresponding author)
5.Soonjoung Kim*, Hongbin Sun*, Diana R. Tomchick, Hongtao Yu, and Xuelian Luo. Structure of Human Mad1 C-terminal Domain Reveals Its Involvement in Kinetochore Targeting. PNAS, (2012) 109:6549-54. (*co-first author)
6.Hongbin Sun, Jiangxin Liu, Jiahai Zhang, Hongda Huang, Haiming Dai, Chao xu, Jihui Wu, and Yunyu Shi. Solution Structure of the Bromodomain of BRD7 and Its Association with Acetylated Peptide. Biochem. Biophys. Res. Commun. (2007) 358:435-441.
7.Hongbin Sun, Haiming Dai, Jiahai Zhang, Shangmin Xiong, Jian Xu, Jihui Wu, and Yunyu Shi. Solution Structure of Calponin Homology Domain of Human MICAL-1. Journal of Biomolecular NMR. (2006) 36:295–300.
3.在研的项目
优秀青年拔尖人才启动经费，500万