职位副教授,硕士生导师
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中山大学“****”引进人才,副教授。一直致力于具有重要药物价值的氮杂环化合物的合成方法学研究及其应用于活性分子合成,近年在国际权威刊物上发表学术论文13篇,其中以第一作者或共同第一作者在Nature子刊Nat. Catal.、Angew. Chem. Int. Ed.、Chem. Sci.和Adv. Synth. Catal.等杂志上7篇,相关工作被Synfacts和Nat. Catal.评论推介。
电子邮箱linweil@mail2.sysu.edu.cn
个人经历2007.09-2011.06???????? 中山大学,化学生物学,理学学士
2011.09-2017.01???????? 中科院上海有机化学研究所,有机化学,理学博士
2017.09-2019.12???????? 瑞士巴塞尔大学,有机化学,博士后
2020.04-至今 ????????? 中山大学药学院(深圳),副教授
研究方向基于含杂原子有机化合物(广泛存在于天然产物以及药物中)的合成新方法,并探索应用于药物化学研究。
科研项目中山大学“****”启动经费
代表论著
1.?????? W. Lin,+ K.-F. Zhang,+ O. Baudoin,* Regiodivergent enantioselective C–H functionalization of Boc-1,3-oxazinanes for the synthesis of β2- and β3-amino acids, Nat. Catal. 2019, 2, 882. (Highlighted in the News & Views by Nat. Catal. 2019, 2, 839)
2.?????? Y. Cui,+W. Lin,+ Y. Zheng, S. Ma,* A metal-catalyzed new approach for alpha-alkynylation of cyclic amines, Chem. Sci. 2019, 10, 1796.
3.?????? H. Luo,+ Z. Yang,+W. Lin,+ Y. Zheng, S. Ma,* A catalytic highly enantioselective allene approach to oxazolines, Chem. Sci. 2018, 9, 1964.
4.?????? W. Lin, S. Ma,* Enantioselective synthesis of naturally occurring isoquinoline alkaloids: (S)-(-)- trolline and (R)-(+)- oleracein E, Org. Chem. Front. 2017, 4, 958.
5.?????? W. Lin, J. Cheng, S. Ma,* Iron(III) Chloride?Catalyzed Tandem Aza-Prins/Friedel-Crafts Cyclization of 2-Arylethyl-2,3-butadienyl Tosylamides and Aldehydes-An Efficient Synthesis of Benzo[f]isoquinolines, Adv. Synth. Catal. 2016, 356, 1989.
6.?????? W. Lin, S. Ma,* Highly efficient and general enantioselective synthesis of naturally occurring isoquinoline alkaloids, Org. Chem. Front. 2014, 1, 338. (Selected as an Inside Front Cover)
7.?????? W. Lin, T. Cao, W. Fan, Y. Han, J. Kuang, H. Luo, B. Miao, X. Tang, Q. Yu, W. Yuan, J. Zhang, C. Zhu, S. Ma,* Enantioselective Double Manipulation on Tetrahydroisoquinolines with Terminal Alkynes and Aldehydes under Copper(I) Catalysis, Angew. Chem. Int. Ed. 2014, 53, 277. (Highlighted by Synfacts 2014, 10, 394)
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