职位中山大学“****”引进人才,副教授,硕士生导师
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电子邮箱dingfq3@mail.sysu.edu.cn
个人经历2019-至今 中山大学 药学院(深圳) “****” 副教授、硕导
2016-2019, 日本理化学研究所(RIKEN), 基础科学特别研究员(SPDR), 合作导师Prof. Yukishige Ito (现为该所Visiting Researcher)
2013-2016, 新加坡南洋理工大学生物工程学院,博士后, 合作导师Prof. Mary Chan
2009-2013, 新加坡南洋理工大学(NTU),博士, 合作导师Prof. Xue-Wei Liu
研究方向课题组致力于糖化学,药物化学及生物医药材料等领域的交叉学科:
1.??????? 糖苷键构建的方法学和策略应用
2.??????? 糖药物分子的设计、合成及药物活性评价
3.??????? 抗菌糖肽、抗菌多糖材料合成与生物医药应用
4.??????? 医药糖蛋白,糖疫苗及糖类抗生素的高效合成应用与开发
代表论著1.??????? Bimodal Glycosyl Donors Protected by 2-O-(ortho-Tosylamido)benzyl Group; F. Ding, A. Ishiwata, and Yukishige Ito, Org. Lett. 2018, 20, 4384-4388.
2.??????? Squaryl group modified phosphoglycolipid analogs as potential modulators of GPR55; F. Ding, A. T. Guy, P. Greimel, H. Kamiguchi, Y. Hirabayashi, Y. Ito, Chem. Commun. 2018, 8470-8473.
3.??????? Stereodivergent Mannosylation Using 2-O-(ortho-Tosylamido)benzyl Group; F. Ding, A. Ishiwata, Y. Ito, Org. Lett. 2018, 20, 4833-4837.
4.??????? Nanoparticles of Short Cationic Peptidopolysaccharide Self-Assembled by Hydrogen Bonding with Antibacterial Effect against Multidrug-Resistant Bacteria; Z. Hou, Y. Shankar, Y. Liu, F. Ding, etal. M. B. Chan-Park, ACS Appl. Mater. Interfaces 2017, 9, 38288-38303.
5.??????? A concise route to the highly-functionalized azetidine precursor: the enantioselective synthesis of penaresidin B; F., R. William, S. Kock, M. Leow, X.-W. Liu, Chem. Commun. 2015, 51, 4639-4642.
6.??????? Interrupted Imino-Nazarov Cyclization of 1-Aminopentadienyl Cation and Related Cascade Process; R. William, S. Wang, F. Ding and X.-W. Liu, Angew. Chem. Int. Ed., 2014, 40, 10742-10746.
7.??????? Directed Orthometalation and the Total Synthesis of Torrubiellone B and N-Deoxymillilarinone A; F. Ding, R. William, M. Leow, H. Chai, J. Fong, X.-W. Liu, Org. Lett. 2014, 16, 26-29.
8.??????? Insight into the programmed ketoreduction of partially reducing polyketide synthases: stereo- and substrate-selectivity of ketoreductase domain; I. Soehano,* L. Yang,* F. Ding,* H. Sun, Z. Low, X. Liu, Z.-X. Liang, Org. Biom. Chem. 2014, 8542-8549.
9.??????? Collective Total Synthesis of 4-Hydroxy-2-pyridone Alkaloids with Antiproliferation Activities ; F. Ding, M. Leow, J.Ma, R. William, H. Liao, X.-W. Liu, Chem.-Asian J. 2014, 2548 – 2554.
10.???? Design and Synthesis of Multivalent neoglycoconjugates by click conjugations; F. Ding, L. Ji, R. William, H. Chai, X.-W. Liu, Beilstein J. Org. Chem. 2014, 10, 1325–1332.
11.???? Ferrier-Type N?Glycosylation: Synthesis of N?Glycosides of Enone Sugars; F. Ding, R. William, X.-W. Liu, J. Org. Chem. 2013, 78, 1293–1299.
12.???? Pathways Leading to 3-Amino- and 3-Nitro-2,3-dideoxy Sugars: Strategies, Synthesis and Their Bioactivities; F. Ding, S. Cai, R. William, X.-W. Liu, RSC Advance 2013, 3, 13594-13621 (Invited Review).
13.???? Synthesis of (R)-Mellein by a Partially Reducing Iterative Polyketide Synthase; H. Sun, C. Ho, F. Ding, X. Liu, Z.-X. Liang, J. Am. Chem. Soc. 2012, 134, 11924 – 11927.
14.???? Direct and Stereoselective Synthesis of 1,3-cis-3-Arylsulphonaminodeoxydisaccharides and Oligosaccharides, F. Ding, R. William, S. Cai, J. Ma, X.-W. Liu, J. Org. Chem. 2012, 77, 5245.
15.???? Triflimide-catalyzed allyl–allyl cross-coupling: a metal-free allylic alkylation; F. Ding, R. William, F. Wang, X.-W. Liu, Chem. Commun. 2012, 48, 8709–8711 (Highlighted by Synfacts 2012, 8, 1142).
16.???? Ready access to 3-amino-2,3-dideoxysugars via regio- and stereo-selectivetandem hydroamination–glycosylation of glycols, F. Ding, R. William, S. Wang, B. Gorityala, X.-W. Liu, Org. Biom. Chem. 2011, 9, 3929.
17.???? A Short and Highly Efficient Synthesisof L-Ristosamine and L-epi-Daunosamine Glycosides; F. Ding, R. William, F. Wang, J. Ma, L. Ji, X.-W. Liu, Org. Lett. 2011, 13, 652.
18.???? A mild and efficient synthetic protocol for Ferrier azaglycosylation promoted by ZnCl2/Al2O3, F. Ding, R. William, B. K. Gorityala, J. Ma, S.. Wang, X.-W. Liu, Tetrahedron Lett. 2010, 51, 3146 (Highlighted by Synfacts 2010, 8, 0965).
19.???? The polymer-supported sulfonic acid catalyzed one-step synthesis of diaminotriphenyl methanes; L. An, F. Ding, J. Zou, Dyes and Pigments 2008, 77, 478;
20.???? Polymer-supported Sulphonic Acid Catalyzed Three-component One-pot Synthesis of α-Amidoalkyl-β-naphthols; L. An, X. Lu, F. Ding, J. Zou, Chinese J. Chem. 2008, 26, 2117;
21.???? Montmorillonite K10: An Efficient Catalyst for Solvent-Free Synthesis of 1,5-Benzodiazepine Derivatives; L. An, F. Ding, J. Zou, Syn. Commun. 2008, 38, 1259.
22.???? Iodine Catalyzed Microwave-Assisted Synthesis of 14-Aryl(Alkyl)-14H-dibenzo[a,j] xanthenes; F. Ding, L. An, J. Zou, Chinese J. Chem. 2007, 25, 645;
23.???? An Efficient and Solvent-Free Reaction for Synthesis of Bis(indol-3-yl)methanes Catalyzed by Sulfamic Acid; L. An, F. Ding, J. Zou, Chinese J. Chem. 2007, 25, 822;
24.? ?2,4-Bis(4-chlorophenyl)-2-methyl-2,3-dihydro-1H-1,5-benzodiazepine; L. An, F. Ding, J. Zou, Acta Cryst. 2007, 63, 3272;
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欢迎加盟
课题组长期招聘合成化学、药物化学、生物材料或医学等相关专业的博士后和特聘科研人员(特聘研究员和特聘副研究员),有意者欢迎将个人简历发到邮箱dingfq3@mail.sysu.edu.cn
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