副教授

职位副教授，硕士生导师

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电子邮箱yuanpy3@mail.sysu.edu.cn

个人经历2004年-2008年 ???中山大学 化学与化学工程学院，获学士学位；
2009年-2013年 ???新加坡国立大学 化学系，获博士学位；
2013年-2018年??? 新加坡国立大学 化学系，研究员；

研究方向靶向药物控释；肿瘤及细菌感染的检测及治疗；纳米生物医学材料。

科研项目1.? 国家自然科学面上项目；角色：主持，状态：进行中；
2.? 深圳市面上项目；角色：主持，状态：进行中；
3. 国家自然科学青年基金项目；角色：主持，状态：进行中；
4. 高校基本科研业务费中山大学青年教师培育项目；角色：主持，状态：进行中；
5. 中山大学“****“启动基金；角色：主持，状态：已结题。

代表论著
1.?P.Y. Yuan⁺,* X. Mao⁺, S. S. Liew, S. Wu, Y. Huang, L. Li, S. Q. Yao*, “Versatile Multiplex Endogenous RNA Detection with Simultaneous Signal Normalization Using Mesoporous Silica Nanoquenchers”, ACS Appl. Mater. Interfaces, 2020, 12, 57695-57709.?Impact Factor:?8.758.
2.?X. Ding⁺*, H.M. Zhao⁺,?Y.Z. Li, A. L. Lee, Z.S. Li, M.J. Fu, C.N. Li, Y. Y. Yang*, P.Y. Yuan*, “Synthetic Peptide Hydrogels as 3D Scaffolds for Tissue Engineering.”?Advanced Drug Delivery Reviews,?2020, 160, 78-104. Impact Factor:?13.300.
3. Y.Z. Li, Y.Y. Gan, C.N. Li, Y. Y. Yang,* P.Y. Yuan,* X. Ding*,?“Cell Membrane-Engineered Hybrid Soft Nanocomposites for Biomedical Applications”, J. Mater. Chem. B, 2020, 8, 5578-5596. Impact Factor: 5.344.
4. P.Y. Yuan, X. Mao, X.F. Wu, S. S. Liew, L. Li, S. Q. Yao, ?“Mitochondria-Targeting Intracellular Delivery of Native Proteins by Using Biodegradable Silica Nanoparticles”, Angew. Chem. Int. Ed., 2019, 58, 7657-7661. Impact Factor: 12.959.
5. X. Mao⁺,?P.Y. Yuan⁺,* C.M. Yu, L. Li,?S. Q. Yao,*?“Nanoquencher-Based Selective Imaging of Protein Glutathionylation in Live Mammalian Cells”,?Angew. Chem. Int. Ed.?2018, 57, 10257-10262. (VIP paper)（+共同第一作者，*共同通讯作者）Impact Factor: 12.959.
6. P.Y. Yuan, X. Ding, Y. Y. Yang, Q.-H. Xu, “Metal Nanoparticles for Diagnosis and Therapy of Bacterial Infection”,?Adv. Healthc. Mater.?2018, 7, **.?Impact Factor:?7.367. (Highlighted in MaterialViews China)
7. P.Y. Yuan, H.L. Zhang, L.H. Qian, X. Mao, S.B. Du, C.M. Yu, B. Peng, S. Q. Yao, “Intracellular Delivery of Functional Native Antibodies under Hypoxic Conditions by Using a Biodegradable Silica Nanoquencher”,?Angew. Chem. Int. Ed.?2017, 56, 12481-12485.?Impact Factor:?12.959.
8. P.Y. Yuan, X. Mao, K. C. Chong, J.Q. Fu, S.J. Pan, S.Z. Wu, C.M. Yu, S. Q. Yao, “Simultaneous Imaging of Endogenous Survivin mRNA and On-Demand Drug Release in Live Cells by Using a Mesoporous Silica Nanoquencher”,?Small, 2017, 13, **.?Impact Factor:?11.459.
9. X.?Ding⁺, P. Yuan⁺, N. Gao, H. Zhu, Y. Y. Yang, Q. Xu, “Au-Ag Core-shell Nanoparticles for Simultaneous Bacterial Imaging and Synergistic Antibacterial Activity”,?Nanomed.-Nanotechnol.?2017, 13, 297-305. (+共同第一作者)Impact Factor:?5.182.?(Highlighted by phys.org)
10. P.Y. Yuan, R.Z. Ma, Q. H. Xu, “Highly Sensitive and Selective Two-Photon Sensing of Cartap Using Au@Ag Core-Shell Nanoparticles”,?Sci. China Chem.?2016, 59, 78-82.?Impact Factor:?6.356.
11. P.Y. Yuan, R.Z. Ma, N.Y. Gao, M. Garai, Q.-H. Xu, “Plasmon Coupling-Enhanced Two-Photon Photoluminescence of Au@Ag Core-shell Nanoparticles and Applications in Nuclease Assay”,?Nanoscale, 2015, 7, 10233-10239.?Impact Factor:?6.895.
12. P. Yuan⁺, X. Ding⁺, Z. Guan, N. Gao, Y. Y. Yang, Q. Xu, “Plasmon‐Coupled Gold Nanospheres for Two‐Photon Imaging and Photoantibacterial Activity”,?Adv. Healthc. Mater.,?2015, 4, 674-678.（+共同第一作者）Impact Factor:?7.367.?(Highlighted in ChemistryViews)
13. P.Y. Yuan, R.Z. Ma, Z.P. Guan, N.Y. Gao, Q. H. Xu, “Tuning Two photon Photoluminescence of Gold Nanoparticle Aggregates with DNA and Its Application as Turn on Photoluminescence Probe for DNA Sequence Detection”,?ACS Appl. Mater. Interfaces, 2014, 6, 13149-13156.?Impact Factor:?8.758.
14. P.Y. Yuan,?Y.H. Lee, M.K. Gnanasammandhan, Z.P. Guan, Y. Zhang, Q.-H. Xu, “Plasmon Enhanced Upconversion Luminescence of NaYF₄:Yb,Er@SiO₂@Ag Core-shell Nanocomposites for Cell Imaging”,?Nanoscale, 2012, 4, 5132-5137.?Impact Factor:?6.895. (Top Ten most-read Nanoscale articles in Q2 of 2014)
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