付饶博士，现任中山大学医学院副教授，硕士研究生导师, 美国神经科学学会、美国酒精滥用研究学会会员。2005年获医学学士学位，2005-2008年工作于辽宁医学院从事解剖学教学和研究工作。2008-2013 年在中山大学中山医学院攻读硕士、博士学位，从事神经损伤与修复的分子机制研究。2013-2019年在美国罗格斯大学历任博士后和副研究员。2019年获聘中山大学，以?“****”青年学术骨干引进到中山大学医学院工作。
付饶博士在美国研究期间致力于酒精成瘾及其伴随的异常情绪神经环路及分子机理研究。前期研究已揭示了和负面情绪密切相关的大脑核团－外侧缰核与吻内侧被盖核团间的谷氨酸传导通路在酒精滥用及抑郁行为中发挥重要调控作用。研究成果发表在《Neuropsychopharmacology》, 《Neuropharmacology》，《Alcoholism: Clinical and Experimental Research》?等SCI期刊杂志，并两次荣获美国酒精滥用研究年会“青年****旅行奖”。
学科专业：?神经生物学、人体解剖学。招生学科专业：071000 生物学，086000 生物与医药。
招生与招聘：本课题组长期招收具有生物学或医学背景的硕士生、博士后及专职科研人员。真诚欢迎有志于神经精神类疾病研究的同学和同行加入。我们将尽力创造更好的实验条件，将学科建设与个人发展的需求相结合，帮助青年科研工作者实现自己的理想与价值。中山大学医学院提供有竞争力的薪酬待遇与职业发展环境。
联系方式：furao5@mail.sysu.edu.cn
著作Fu, R., Zuo, W., Shiwalkar, N., Mei, Q., Fan, Q., Chen, X., Li, J., Bekker, A., Ye, J. H., 2019. Alcohol withdrawal drives depressive behaviors by activating neurons in the rostromedial tegmental nucleus. Neuropsychopharmacology?44, 1464-1475. IF= 7.1
?Fu, R., X. Chen, W. H. Zuo, J. Li, S. Kang, L. H. Zhou, A. Siegel, A. Bekker and J. H. Ye (2016). "Ablation of mu opioid receptor-expressing GABA neurons in rostromedial tegmental nucleus increases ethanol consumption and regulates ethanol-related behaviors.” Neuropharmacology?107: 58-67.?IF= 4.2
?Fu R, W. H. Zuo, D. Gregor, J. Li, D. Grech and J. H. Ye (2016). "Pharmacological Manipulation of the Rostromedial Tegmental Nucleus Changes Voluntary and Operant Ethanol Self-Administration in Rats.” Alcohol Clin Exp Res?40(3):572-82.?IF= 3.2
Tang, Y#., R. Fu#, Z. M. Ling, L. L. Liu, G. Y. Yu, W. Li, X. Y. Fang, Z. Zhu, W. T. Wu and L. H. Zhou (2018). "MiR-137-3p rescue motoneuron death by targeting calpain-2." Nitric Oxide?74: 74-85. IF= 4.3?(co-first author)
Fu, R., Y. Tang, Z. M. Ling, Y. Q. Li, X. Cheng, F. H. Song, L. H. Zhou and W. T. Wu (2014). "Lithium enhances survival and regrowth of spinal motoneurons after ventral root avulsion." BMC Neurosci?15: 84.?IF= 2.1
Fu, R., L. Q. Wang, G. L. Chu and L. H. Zhou (2012). "Involvement of phospholipase C-gamma in the pro-survival role of glial cell line-derived neurotrophic factor in developing motoneurons in rat spinal cords." Mol Med Rep?6(4): 805-810. IF= 1.9
Fu, R., D. Gregor, Z. Peng, J. Li, A. Bekker and J. H. Ye (2015). "Chronic intermittent voluntary alcohol drinking induces hyperalgesia in Sprague-Dawley rats." Int J Physiol Pathophysiol Pharmacol?7(3): 136-144.?
Fu, R., Q. Mei, W. Zuo, J. Li, D. Gregor, A. Bekker and J. H. Ye (2017). "Low-dose ethanol excites lateral habenula neurons projecting to VTA, RMTg, and raphe." Int J Physiol Pathophysiol Pharmacol?9(6): 217-230.
Zuo, W. H., R. Fu, F. W. Hopf, G. Xie, K. Krnjevic, J. Li and J. H. Ye (2017). "Ethanol drives aversive conditioning through dopamine 1 receptor and glutamate receptor-mediated activation of lateral habenula neurons." Addict Biol?22(1): 103-116.?IF= 5.6?
Ye, J. H., R. Fu?and W. He (2017). "The rostromedial tegmental nucleus and alcohol addiction." Oncotarget?8(12): 18624-18625.?
Cheng, X., R. Fu, M. Gao, S. Liu, Y. Q. Li, F. H. Song, I. C. Bruce, L. H. Zhou and W.T. Wu (2013). "Intrathecal application of short interfering RNA knocks down c-jun expression and augments spinal motoneuron death after root avulsion in adult rats." Neuroscience?241: 268-279.?IF= 3.3?
Liu, S., R. Fu, X. Cheng, S. P. Chen and L. H. Zhou (2012). "Exploring the binding of BACE-1 inhibitors using comparative binding energy analysis (COMBINE)." BMC Struct Biol?12: 21.?IF= 2.7
Cui, J., R. Fu, L. H. Zhou, S. P. Chen, G. W. Li, S. X. Qian and S. Liu (2013). "BCR-ABL tyrosine kinase inhibitor pharmacophore model derived from a series of phenylaminopyrimidine-based (PAP) derivatives." Bioorg Med Chem Lett?23(8): 2442-2450.?IF= 2.7?
Gregor, D.M., W. Zuo, R. Fu, A. Bekker and J. H. Ye (2019). "Elevation of Transient Receptor Potential Vanilloid 1 Function in the Lateral Habenula Mediates Aversive Behaviors in Alcohol-withdrawn Rats." Anesthesiology?IF= 6.5
Li, J., W. Zuo, R. Fu, G. Xie, A. Kaur, A. Bekker and J. H. Ye (2016). "High Frequency Electrical Stimulation of Lateral Habenula Reduces Voluntary Ethanol Consumption in Rats." Int J Neuropsychopharmacol?IF= 3.9
Li, Y. Q., Y. Tang, R. Fu, Q. H. Meng, X. Zhou, Z. M. Ling, X. Cheng, S. W. Tian, G. J. Wang, X. G. Liu and L. H. Zhou (2015). "Efficient labeling in vitro with non-ionic gadolinium magnetic resonance imaging contrast agent and fluorescent transfection agent in bone marrow stromal cells of neonatal rats." Mol Med Rep?12(1): 913-920.?IF= 1.9
Tang, Y., Z. M. Ling, R. Fu, Y. Q. Li, X. Cheng, F. H. Song, H. X. Luo and L. H. Zhou (2014). "Time-specific microRNA changes during spinal motoneuron degeneration in adult rats following unilateral brachial plexus root avulsion: ipsilateral vs. contralateral changes." BMC Neurosci?15: 92.?IF= 2.1?
Shiwalkar N, D. Gregor, R. Fu, A. Bekker and J. H. Ye (2017) Changes in Alcohol-Related Behavior Following an Incident of Traumatic Brain Injury. J Trauma Treat?6: 392. doi:10.4172/2167-1222.**.
Kang, S., J. Li, W. Zuo, R. Fu, D. Gregor, K. Krnjevic, A. Bekker and J. H. Ye (2017). "Ethanol Withdrawal Drives Anxiety-Related Behaviors by Reducing M-type Potassium Channel Activity in the Lateral Habenula." Neuropsychopharmacology?42(9): 1813-1824.?IF= 6.5?
Zuo, W., L. Wang, L. Chen, K. Krnjevic, R. Fu, X. Feng, W. He, S. Kang, A. Shah, A. Bekker and J. H. Ye (2017). "Ethanol potentiates both GABAergic and glutamatergic signaling in the lateral habenula." Neuropharmacology?113(Pt A): 178-187.?IF= 4.2
Shah, A., W. Zuo, S. Kang, J. Li, R. Fu, H. Zhang, A. Bekker and J. H. Ye (2017). "The lateral habenula and alcohol: Role of glutamate and M-type potassium channels." Pharmacol Biochem Behav?162: 94-102.?IF= 2.7?
Cheng, X., S. Liu, Y. Q. Wang, Y. Q. Li, R. Fu, Y. Tang, W. H. Zheng and L. H. Zhou (2012). "Suppression of c-jun influences nNOS expression in differentiated PC12 cells." Mol Med Rep?6(4): 750-754.?IF= 1.9
Zhao, X. C., L. L. Wang, Y. Q. Wang, F. H. Song, Y. Q. Li, R. Fu, W. H. Zheng, W. Wu and L. H. Zhou (2012). "Activation of phospholipase-Cgamma and protein kinase C signal pathways helps the survival of spinal motoneurons injured by root avulsion." J Neurochem?121(3): 362-372.?IF= 4.6
Wang, L. L., X. C. Zhao, L. F. Yan, Y. Q. Wang, X. Cheng, R. Fu?and L. H. Zhou (2011). "C-jun phosphorylation contributes to down regulation of neuronal nitric oxide synthase protein and motoneurons death in injured spinal cords following root-avulsion of the brachial plexus." Neuroscience?189: 397-407.?IF= 3.3
研究方向我国是饮酒大国，酒精滥用常引发各种神经精神类疾病，给人民健康带来严重危害。虽然急性酒精作用常给人带来欣快感，但慢性酒精滥用及戒断常引发焦虑、抑郁甚至疼痛症状，这些负面情绪驱使滥用者寻求自我给药，以期移除这些不良情绪。但“借酒消愁愁更愁”，滥用者难以逃脱滥用—戒断—负面情绪—复吸的循环规律，这是药物滥用一旦沾染难以戒掉的原因之一。我们课题组前期研究已发现和外侧缰核与吻内侧被盖核团间的谷氨酸传导通路在酒精滥用及抑郁行为中发挥重要调控作用。未来工作将紧密参与我国“脑科学计划”，广泛采用蛋白组学、电生理、药理学、脑立体定位、组织学、化学遗传学及光遗传学等技术手段，在基因层面探索吻内侧被盖核团参与药物成瘾、疼痛和抑郁症调控的分子机制。
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