反馈相关负波与成瘾

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本站小编 Free考研考试/2022-01-01

陈乐乐, 黄蓉, 贾世伟(

)

山东师范大学心理学院, 济南 250358

收稿日期:2019-07-17出版日期:2020-06-15发布日期:2020-04-22
通讯作者:贾世伟E-mail:jiashiwei82@126.com

基金资助:* 国家自然科学基金青年项目(NSFC31200784)

Feedback-related negativity and addiction

CHEN Lele, HUANG Rong, JIA Shiwei(

)

School of Psychology, Shandong Normal University, Jinan 250358, China

Received:2019-07-17Online:2020-06-15Published:2020-04-22
Contact:JIA Shiwei E-mail:jiashiwei82@126.com

摘要/Abstract

摘要： 反馈相关负波(feedback-related negativity, FRN)是反馈加工诱发的脑电成分, 体现了个体对奖赏的敏感性。成瘾分为物质成瘾和行为成瘾, 两类个体的反馈加工都呈现病理性模式。相对于普通反馈物(如金钱), 物质成瘾个体在加工成瘾物质时诱发的FRN波幅显著增大; 在与非成瘾被试的对照研究中, 物质成瘾者加工金钱反馈时的FRN也表现出与成瘾相关的异常模式; 在行为成瘾个体中亦观察到与物质成瘾个体类似的FRN失调现象。但以往多数研究中对成瘾类型的区分还不够详细, 未来研究应进一步考虑成瘾不同亚型的特点; 且成瘾个体往往伴随其他精神障碍(如抑郁、焦虑), 将来的研究要区分共病因素的影响, 揭示成瘾独特的奖赏加工机制问题。

图/表 2

图1成瘾、中脑多巴胺系统与FRN示意图注:成瘾物质摄入后作用于中脑多巴胺系统, 增加中脑腹侧被盖区(the ventral tegmental area, VTA)中多巴胺神经元冲动, 使前扣带回(anterior cingulate cortex, ACC)及伏隔核(nucleus accumben, NAc)中多巴胺水平增加产生快感, 带来强化效应, 同时造成FRN失调。

成瘾研究	成瘾物质/行为	程度	N	诊断标准/工具	实验任务	FRN
物质成瘾
Baker et al., 2011	Pol.	亚临床	18	ASSIST	赌博*	普通奖赏物 ↓
Baker et al., 2016	Pol.	亚临床	195	ASSIST	赌博	普通奖赏物 ↓
Baker, Wood, & Holroyd, 2016	Pol.	亚临床	12	ASSIST	赌博	成瘾物质 ↑
Baker et al., 2017	烟草	亚临床	20	FTND	赌博	成瘾物质 ↑
Fein et al., 2008	酒精	临床	22	DSM-Ⅳ	BART	普通奖赏物 ↓
Franken et al., 2010	酒精	正常	47	QFV-I	RPT	普通奖赏物 ↑
Hixson et al., 2019	酒精	临床	15	DSM-Ⅳ	GRT	普通奖赏物 ↑
Kamarajan et al., 2010	酒精	临床	40	DSM-Ⅳ	赌博	普通奖赏物 ↓
Morie et al., 2016	可卡因	临床	23	DSM-Ⅳ	快速反应任务	普通奖赏物 ↓
Muñoz et al., 2012	烟草	亚临床	32	FTND	预测任务	成瘾物质 ↑
Parvaz et al., 2015	可卡因	临床	50	临床访谈	门任务	普通奖赏物 ↓
Potts et al., 2014	烟草	亚临床	22	DSM-Ⅳ	RPT	普通奖赏物 ↑
Soder et al., 2019	酒精	正常	85	DDQ-R	RPT, BART	普通奖赏物 ↓
Wei et al., 2018	甲基苯丙胺	临床	21	DSM-Ⅴ	赌博	普通奖赏物 ↑
行为成瘾
Hewig et al., 2010	赌博	临床	20	DSM-Ⅳ	真实赌博	普通奖赏物 ↑
He et al., 2017	网络	亚临床	16	临床访谈	赌博	普通奖赏物 ↓
Lole et al., 2015	赌博	亚临床	16	PGSI	赌博	普通奖赏物 ↓
Li et al., 2019	网络	临床	34	DSM-Ⅴ	赌博	普通奖赏物 ↓
Oberg et al., 2011	赌博	亚临床	15	CPGI	IGT	普通奖赏物 ↑
Torres et al., 2013	赌博	临床	21	DSM-Ⅳ	反转学习	普通奖赏物 ↓
Ulrich et al., 2018	赌博	亚临床	20	DSM-Ⅳ	赌博	普通奖赏物 ↓
Yau et al., 2015	网络	亚临床	39	临床访谈	BART	普通奖赏物 ↓

表1成瘾障碍与FRN相关研究

成瘾研究	成瘾物质/行为	程度	N	诊断标准/工具	实验任务	FRN
物质成瘾
Baker et al., 2011	Pol.	亚临床	18	ASSIST	赌博*	普通奖赏物 ↓
Baker et al., 2016	Pol.	亚临床	195	ASSIST	赌博	普通奖赏物 ↓
Baker, Wood, & Holroyd, 2016	Pol.	亚临床	12	ASSIST	赌博	成瘾物质 ↑
Baker et al., 2017	烟草	亚临床	20	FTND	赌博	成瘾物质 ↑
Fein et al., 2008	酒精	临床	22	DSM-Ⅳ	BART	普通奖赏物 ↓
Franken et al., 2010	酒精	正常	47	QFV-I	RPT	普通奖赏物 ↑
Hixson et al., 2019	酒精	临床	15	DSM-Ⅳ	GRT	普通奖赏物 ↑
Kamarajan et al., 2010	酒精	临床	40	DSM-Ⅳ	赌博	普通奖赏物 ↓
Morie et al., 2016	可卡因	临床	23	DSM-Ⅳ	快速反应任务	普通奖赏物 ↓
Muñoz et al., 2012	烟草	亚临床	32	FTND	预测任务	成瘾物质 ↑
Parvaz et al., 2015	可卡因	临床	50	临床访谈	门任务	普通奖赏物 ↓
Potts et al., 2014	烟草	亚临床	22	DSM-Ⅳ	RPT	普通奖赏物 ↑
Soder et al., 2019	酒精	正常	85	DDQ-R	RPT, BART	普通奖赏物 ↓
Wei et al., 2018	甲基苯丙胺	临床	21	DSM-Ⅴ	赌博	普通奖赏物 ↑
行为成瘾
Hewig et al., 2010	赌博	临床	20	DSM-Ⅳ	真实赌博	普通奖赏物 ↑
He et al., 2017	网络	亚临床	16	临床访谈	赌博	普通奖赏物 ↓
Lole et al., 2015	赌博	亚临床	16	PGSI	赌博	普通奖赏物 ↓
Li et al., 2019	网络	临床	34	DSM-Ⅴ	赌博	普通奖赏物 ↓
Oberg et al., 2011	赌博	亚临床	15	CPGI	IGT	普通奖赏物 ↑
Torres et al., 2013	赌博	临床	21	DSM-Ⅳ	反转学习	普通奖赏物 ↓
Ulrich et al., 2018	赌博	亚临床	20	DSM-Ⅳ	赌博	普通奖赏物 ↓
Yau et al., 2015	网络	亚临床	39	临床访谈	BART	普通奖赏物 ↓

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