行为干预情绪记忆再巩固：从实验室到临床转化

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陈伟¹^,²^,³, 李俊娇⁴, 林小裔¹, 张晓霞¹, 郑希付¹^,²^,³(

)

1 华南师范大学心理学院
2 华南师范大学心理应用研究中心, 广州 510631
3 广东省心理健康与认知科学重点实验室, 广州 510631
4 广东第二师范学院教师教育学院, 广州 510303

收稿日期:2019-05-12出版日期:2020-02-15发布日期:2019-12-25
通讯作者:郑希付E-mail:zhengxf@scnu.edu.cn

基金资助:* 国家自然科学基金项目(31771218);国家自然科学基金项目(31970996);华南师范大学研究生创新计划项目(2018WKXM004);幸福广州心理服务与辅导基地资助

Behavioral intervention of emotional memory reconsolidation: From bench to bedside

CHEN Wei¹^,²^,³, LI Junjiao⁴, LING Xiaoyi¹, ZHANG Xiaoxia¹, ZHENG Xifu¹^,²^,³(

)

1 School of Psychology, South China Normal University, Guangzhou 510631, China
2 Center for Studies of Psychological Application, South China Normal University, Guangzhou 510631, China
3 Guangdong Key Laboratory of Mental Health and Cognitive Science, Guangzhou 510631, China
4 College of Teacher Education, Guangdong University of Education, Guangzhou 510303, China

Received:2019-05-12Online:2020-02-15Published:2019-12-25
Contact:ZHENG Xifu E-mail:zhengxf@scnu.edu.cn

摘要/Abstract

摘要： 重新激活已经储存的记忆会重返暂时不稳定的状态, 需要经历重新稳定, 称为记忆再巩固。在这期间可以通过多种行为手段破坏、强化或更新原始记忆痕迹, 这为开发一种革命性的情绪记忆障碍治疗方法开辟了道路。然而, 即使在简单的实验模型中引发记忆再巩固的条件也是复杂的, 这给临床转化带来了困难与挑战。未来研究可以设置更具生态效应的基础模型, 寻求引发以及干预再巩固的最佳方式, 从神经生理、细胞分子层面进一步深化其内在机理研究。

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