高固多相生物反应工程

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王岚¹，刘阳^1,2，陈洪章¹?

1. 中国科学院过程工程研究所生物质炼制工程北京市重点实验室，北京 100190 2. 中国科学院大学化学工程学院，北京 100190

收稿日期:2018-06-12修回日期:2018-07-25出版日期:2018-10-22发布日期:2018-10-12
通讯作者:陈洪章

基金资助:中国科学院洁净能源先导科技专项;2017年度北京创新基地培育与发展专项基金

High-solid and multi-phases bio-reaction engineering

Lan WANG¹, Yang LIU^1,2, Hongzhang CHEN^1*

1. Beijing Key Laboratory of Biorefining Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China
2. School of Chemical Engineering, University of Chinese Academy of Sciences, Beijing 100190, China

Received:2018-06-12Revised:2018-07-25Online:2018-10-22Published:2018-10-12
Contact:CHEN Hong-zhang

摘要/Abstract

摘要： 以木质纤维素高固酶解发酵为例，高固形物及其复杂的理化性质会导致体系出现“固体效应”和“水束缚效应”，形成传质速度较低的固液气和微生物复杂多相体系，影响木质纤维素生物转化速率；同时，固形物增加及由此产生的高固酶解发酵流变学特性使以剪切力为主导的机械搅拌在高固多相体系下具有不适应性(会导致酶或微生物活性降低)，从而对搅拌方式、反应器及过程设计放大等提出新的要求. 本工作基于课题组多年的研究，提出高固多相生物反应工程的理念，从固体基质特性入手剖析影响高固多相生物反应速率的关键因素，提出了以周期法向力为动力源的过程强化方法，开发出周期蠕动高固多相生物反应系统，以期为高固多相生物反应工程研究提供理论和技术支持.

引用本文

王岚刘阳陈洪章. 高固多相生物反应工程[J]. 过程工程学报, 2018, 18(5): 918-923.
Lan WANG Yang LIU Hongzhang CHEN. High-solid and multi-phases bio-reaction engineering[J]. Chin. J. Process Eng., 2018, 18(5): 918-923.

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