姓名：王艳 性别：女 职称：教授 招生院所：基础医学院 招生类型：科学学位(博) 科学学位(硕) 招生专业：生物化学与分子生物学(博) 生物化学与分子生物学(硕) 研究方向名称：肿瘤发生与转移的表观遗传调控机制 电子信箱：yanwang@ccmu.edu.cn


社会任职
1. 肿瘤侵袭和转移机制研究北京市重点实验室主任
个人简历
重要学术论文
1. Riuqiong Liu#, Jie Gao#, Yang Yang, Rongfang Qiu, Yu Zheng, Wei Huang, Yi Zeng, Yongqiang Hou, Shuang Wang, Shuai Leng, Dandan Feng, Wenqiang Yu, Gancheng Sun, Hang Shi, Xu Teng, Yan Wang*.PHD Finger Protein 1 (PHF1) is a Novel Reader for Histone H4R3 Symmetric Dimethylation and Coordinates with PRMT5-WDR77/CRL4B Complex to Promote Tumorigenesis. Nucleic Acids Research. 2018,46(13):6608-6626.SCI
2. Yang Yang#, Wei Huang#，Qiu Rongfang, Liu Ruiqiong, Zeng Yi, Gao Jie, Zheng Yu, Hou Yongqiang, Wang Shuang, Yu Wenqiang, Leng Shuai, Feng Dandan, Yan Wang*.LSD1 coordinates with the SIN3A/HDAC complex and maintains sensitivity to chemotherapy in breast cancer. Journal of Molecular Cell Biology. 2018,10(4):285-301.SCI
3. Jie Gao, Yang Yang, Rongfang Qiu, Kai Zhang, Xu Teng, Riuqiong Liu* and Yan Wang*.Proteomic analysis of the OGT interactome: novel links to epithelial–mesenchymal transition and metastasis of cervical cancer. Carcinogenesis. 2018,39(10):1222-1234.SCI
4. Wenzhe Si, Wei Huang,Yu Zheng, Yang Yang, Xujun Liu, Lin Shan, Xing Zhou, Yue Wang, Dongxue Su, Jie Gao, Ruorong Yan, Xiao Han, Wanjin Li, Lin He, Lei Shi, Chenghao Xuan, Jing Liang, Luyang Sun, Yan Wang*, and Yongfeng Shang *.Dysfunction of the Reciprocal Feedback Loop between GATA3- and ZEB2-Nucleated Repression Programs Contributes to Breast Cancer Metastasis. Cancer Cell . 2015,27:822-36.SCI
5. Yang Yang, Ruiqiong Liu, Rongfang Qiu, Yu Zheng, Wei Huang, Huili Hu, Qinghong Ji, Housheng He, Yongfeng Shang, Yaoqin Gong and Yan Wang*.CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1/DNMT3A in DNA methylation-based epigenetic silencing. Oncogene. 2015,34:104-18.SCI
6. Huili Hu, Yang Yang, Qinghong Ji, Wei Zhao,Baichun Jiang, Ruiqiong Liu, Jupeng Yuan, Qiao Liu, Xi Li, Yongxin Zou, Changshun Shao, Yongfeng Shang, Yan Wang*, and Yaoqin Gong*.CRL4B catalyzes H2AK119 monoubiquitination and coordinates with PRC2 to promote tumorigenesis. Cancer Cell . 2012,22:781-95.SCI
主编或副主编的著作/译著
重要奖项
1. 中源协和生命医学创新突破奖 201811
2. “青年拔尖人才” 国家级 201709
3. 乳腺癌发生发展的表观遗传机制 国家自然科学二等奖 国家级 201612
4. “创新人才推进计划”中青年科技创新领军人才 国家级 201502
5. “百千万人才工程”国家级人选 国家级 201502
6. 表观遗传转录调控与肿瘤发生与转移 国家自然基金委优秀青年基金 国家级 201401
7. “新世纪优秀人才支持计划” 国家级 201212