姓名：李人 性别：女 职称：研究员、教授 招生院所：脑重大疾病研究院 招生类型：科学学位(博) 科学学位(硕) 招生专业：神经病学(博) 神经病学(硕) 研究方向名称：精神病的分子机制研究 电子信箱：renali@ccmu.edu.cn


社会任职
1. 北京脑重大疾病研究院精神分裂症研究所所长
2. 美国南佛罗里达大学教授
3. 美国罗斯维而研究所神经内分泌研究中心资深研究院兼任主任
个人简历
1. 198009-198309:上海体育学院运动生理学 硕士
2. 198710-198910:美国纽约州立大学生物系 访问
3. 198805-198809:荷兰皇家科学院分子生物研究所 访问
4. 198911-199306:美国国立健康研究院精神疾病研究所 访问
5. 199306-199706:美国路易斯维尔大学医学院精神科 科研副教授
6. 199306-199712:University of Louisville Medical School 神经科学博士
7. 199706-199906:美国REGENESIS生物公司 研究员
8. 199906-201009:美国太阳健康研究所神经内分泌中心 研究员兼中心主任
9. 201009-201409:美国罗斯坎普研究所神经内分泌和国际生物医学教育中心 资深研究员，中心主任
10. 201409-:北京脑重大疾病研究院 教授
重要学术论文
1. Zhang Z, Ciu J, Gao F, Li Y, Zhang G, Liu M, Yan R, Shen Y, Li R*.Elevated cleavage of neuregulin-1 by beta-secretase 1 in plasma of schizophrenia patients. Prog Neuropsychopharmacol Biol Psychiatry. 2019,90:161-168.SCI
2. Ma L, Xu Y, Wang G, Li R*.What do we know about sex differences in depression: a review of animal models and potential mechanisms . Prog Neuropsychopharmacol Biol Psychiatr. 2019,89::48-56.SCI
3. Ma L, Xu Y, Jiang W, Li Y, Zhang X, Wang G*, Li R*.Sex Differences in Antidepressant Effect of Sertraline in Transgenic Mouse Models. Fronters in Cellular Neuroscience. 2019,13:24.SCI
4. Shen Y,Wang H, Sun Q, Yao H, Keegan A, Mullan M, Wilson J, Lista S, Leyhe T,Laske C,Rujescu D,Levey A, Wallin A,Blennow K, Li R*, Hampel.Increased Plasma Beta-Secretase 1 May Predict Conversion to Alzheimer's Disease Dementia in Individuals With Mild Cognitive Impairment. Biological Psychiatry. 2018,83(5):447-455.SCI
5. Wan L, Li Y, Zhang Z, Sun Z, He Y, Li R*.Methylenetetrahydrofolate reductase and psychiatric diseases.. Translational Psychiatry. 2018,8(1):242.SCI
6. Xu Y, Ma L, Jiang W, Li Y, Wang G*, Li R*.Studies of sex differences in duloxetine efficacy for depression in transgenic mouse models. Frontiers in Cellular Neuroscience. 2017,11:344.SCI
7. Sun Q, Xie N, Tang B, Li R*, Shen Y*.Alzheimer’s disease: from genetic variants to the distinct pathological mechanisms. Frontiers in Molecular Neuroscience . 2017,10:319.SCI
8. Cheng X, Shen Y, Li R*.Targeting TNF: a therapeutic strategy for Alzheimer's disease.. Drug Discov Today. 2014,19(11):1822-1827.SCI
9. Konishi Y, Yang L, He P, Lindholm K, Lu B, Li R*, Shen Y*.Deficiency of GDNF Receptor GFRalpha1 in Alzheimer's Neurons Results in Neuronal Death. J Neurosci. 2014,34(39):13127-13138.SCI
10. Li R*, Singh M.Sex differences in cognitive impairment and Alzheimer's disease. Frontiers in Neuroendocrinology. 2014,35(3):385-403.SCI
11. 17.Cui J, Jothishankar B, He P, Staufenbiel M, Shen Y, Li R*.Amyloid precursor protein mutation disrupts reproductive experience-enhanced normal cognitive development in a mouse model of Alzheimer's disease. Mol Neurobiology. 2014,49(1):103-112.SCI
12. Li R#*, Cui J, Shen Y.Brain sex matters: Estrogen in cognition and Alzheimer's disease.. Mol Cell Endocrinology. 2014,389(1-2):13-21.SCI
13. Jiang H, He P, Xie J, Staufenbiel M, Li R*, Shen Y*.Genetic deletion of TNFRII gene enhances the Alzheimer-like pathology in an APP transgenic mouse model via reduction of phosphorylated IkBa. Human Molecular Genetics. 2014,23(18):4906-4918.SCI
14. He P,Staufenbiel M, Li R*, Shen Y*.Deficiency of Patched 1-induced Gli 1 signal transduction results in astrogenesis in Swedish mutated APP transgenic mice. Human Molecular Genetics. 2014,23(24):6512-6527.SCI
主编或副主编的著作/译著
重要奖项