姓名：杨小枫 性别：男 职称：教授 招生院所：脑重大疾病研究院 招生类型：科学学位(博) 科学学位(硕) 招生专业：神经病学(博) 神经病学(硕) 研究方向名称：癫痫的发病机制及新型抗癫痫技术的研发 电子信箱：**@163.com


社会任职
1. 中国抗癫痫协会理事
2. 中国医药生物技术协会组织生物样本库分会低温生物组副组长
3. 北京抗癫痫协会常务理事
4. 北京神经内科学会癫痫专业委员会副主任委员
个人简历
1. 197807-198307:北京医科大学(现北京大学医学部) 本科学习
2. 198307-198807:张家口医学院 住院医师
3. 198807-199107:中国医学科学院 北京协和医科大学 硕士研究生
4. 199107-199207:北京协和医科院 主治医师
5. 199207-199407:美国密苏里大学医学院 博士后访问
6. 199407-199907:美国密苏里大学医学院神经外科 研究员
7. 199907-200207:美国圣路易斯华盛顿大学医学院神经科 博士后研究
8. 200207-200707:美国圣路易斯华盛顿大学医学院神经科 科研助理教授
9. 200707-201312:美国明尼苏达大学医学院神经科 副教授
10. 201208-:北京市海淀医院功能神经科 客座教授
11. 201311-:北京首都医科大学/脑重大疾病研究院/宣武医院 教授/研究员
重要学术论文
1. Ren GP, Yan JQ, Yu ZX, Wang D, Li XN, Mei SS, Dai JD, Li XL, Li YL, Wang XF, Yang XF*.Automated Detector of High Frequency Oscillations in Epilepsy Based on Maximum Distributed Peak Points. Int J Neural Syst. 2018,28：（1）:**.SCI
2. 1.Zuo R, Wei J, Li X, Li C, Zhao C, Ren Z, Liang Y, Geng X, Jiang C, Yang X * Zhang X*.Automated Detection of High-Frequency Oscillations in Epilepsy Based on a Convolutional Neural Network. Front. Comput. Neurosci. 2018,13：（6）:【未填写起止页码】.SCI
3. 2.Jiang CL, Li X, Yan J, Yu T, Wang X, Ren Z, Li D, Liu C, Du W, Zhou X, Xing Y, Ren G, Zhang G*, Yang X* .Determining the Quantitative Threshold of High-Frequency Oscillation Distribution to Delineate the Epileptogenic Zone by Automated Detection. Front Neurol. 2018,13：（9）:889.SCI
4. 4.Ren GP#, Yan JQ#, Tao GX, Gan YM, Li DH, Yan X, Fu YJ, Wang LM, Wang WM, Zhang ZM, Yue F, Yang XF*.Rapidly focal cooling terminates cortical epilepsy on monkeys. Experimental Neurology. 2017,(295):202–210.SCI
5. Donghong Li and Xiaofeng Yang.Remote modulation of network excitability during deep brain stimulation for epilepsy.. Seizure. 2017,47（4）:42-50.SCI
6. 5.Wang D, Yu ZX, Yan JQ, Xue FQ, Ren GP, Jiang CX, Wang WM, Piao YS, Yang XF*.Photolysis of Caged-GABA rapidly terminates seizures in vivo: concentration- and light intensity-dependence. Frontiers in neurology. 2017,18：（8）:215.SCI
7. Xiaofeng Yang,Anna L.Meehan,Steven M.Rothman,Janet M.Dubinsky.Seletracetam enhances short term depression in vitro. Eplepsy Research. 2015,117:17-22.SCI
8. Matthew D.Smyth,MD,Rowland H.Han,MSE,Chester K.Yarbrough,MD,Edward E.Patterson,DVM,PhD,Xiao-Feng Yang,MD,John W.Miller,MD,PhD,Steven M.Rothman,MD,and Raimondo D'Ambrosio,PhD.Temperatures achieved in human and canine neocortex during intraoperative passive or active focal cooling. Therapeutic Hypothermia and Temperature Management. 2015,5(2):95-103.SCI
9. Meehan AL, Yang XF, Yuan L, Rothman SM.Levetiracetam has an activity-dependent effect on inhibitory transmission. Epilepsia. 2012,Mar;53(3):469-76.SCI
10. Yang XF, Rode DL, Peterka DS, Yuste R, Rothman SM.Optical control of focal epilepsy in vivo with caged γ-aminobutyric acid.. Ann Neurol. 2012,Jan;71(1):68-75.SCI
11. Meehan AL, Yang XF, McAdams BD, Yuan L, Rothman SM.A new mechanism for antiepileptic drug action: vesicular entry may mediate the effects of levetiracetam. J Neurophysiol. 2011,Sep;106(3):1227-39.SCI
12. Yang XF, Schmidt BF, Rode DL, Rothman SM.Optical suppression of experimental seizures in rat brain slices. Epilepsia . 2010,Jan;51(1):127-135.SCI
13. Yang XF, Rothman SM.Levetiracetam has a time- and stimulation-dependent effect on synaptic transmission. Seizure . 2009,Nov;18(9):615-9.SCI
14. Xu L, Rensing N, Yang XF, Zhang HX, Thio LL, Rothman SM, Weisenfeld AE, Wong M, Yamada KA.Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents. J Clin Invest . 2008,Jan;118(1):272-80.SCI
15. Ouyang Y, Yang XF, Hu XY, Erbayat-Altay E, Zeng LH, Lee JM, Wong M.Hippocampal seizures cause depolymerization of filamentous actin in neurons independent of acute morphological changes. Brain Res . 2007,Apr 27;1143:238-46.SCI
16. Rothman SM, Perry G, Yang XF, Hyrc K, Schmidt BF.Optical suppression of seizure-like activity with an LED. Epilepsy Res . 2007,May;74(2-3):201-9.SCI
17. Yang XF, Weisenfeld A, Rothman SM.Prolonged exposure to levetiracetam reveals a presynaptic effect on neurotransmission. Epilepsia. 2007,Oct;48(10):1861-9.SCI
18. Yang XF, Kennedy BR, Lomber SG, Schmidt RE, Rothman SM.Cooling produces minimal neuropathology in neocortex and hippocampus. Neurobiol Dis. 2006,Sep;23(3):637-43.SCI
19. Rothman SM, Smyth MD, Yang XF, Peterson GP.Focal cooling for epilepsy: an alternative therapy that might actually work. Epilepsy Behav . 2005,Sep;7(2):214-21.SCI
20. Rensing N, Ouyang Y, Yang XF, Yamada KA, Rothman SM, Wong M.In vivo imaging of dendritic spines during electrographic seizures. Ann Neurol . 2005,Dec;58(6):888-98.SCI
21. Yang XF, Ouyang Y, Kennedy BR, Rothman SM.Cooling blocks rat hippocampal neurotransmission by a presynaptic mechanism: observations using 2- photon microscopy. J Physiol . 2005,Aug 15;567(Pt 1):215-24.SCI
22. Chang JH, Yang XF, Zempel JM, Rothman SM.The unilateral cobalt wire model of neocortical epilepsy: a method of producing subacute focal seizures in rodents. Epilepsy Res . 2004,Sep-Oct;61(1-3):153-60.SCI
23. Yang XF, Chang JH, Rothman SM.Long-lasting anticonvulsant effect of focal cooling on experimental neocortical seizures. Epilepsia. 2003,Dec;44(12):1500-5.SCI
24. Rothman S, Yang XF.Local cooling: a therapy for intractable neocortical epilepsy. Epilepsy Curr . 2003,Sep;3(5):153-156.SCI
25. Yang XF, Chang JH, Rothman SM.Intracerebral temperature alterations associated with focal seizures. Epilepsy Res . 2002,Dec;52(2):97-105.SCI
26. Yang XF, Duffy DW, Morley RE, Rothman SM.Neocortical seizure termination by focal cooling: temperature dependence and automated seizure detection. Epilepsia. 2002,Mar;43(3):240-5.SCI
27. Yang XF, Rothman SM.Focal cooling rapidly terminates experimental neocortical seizures. Ann Neurol . 2001,Jun;49(6):721-6.SCI
28. Barone CM, Jimenez DF, Huxley VH, Yang XF.In vivo visualization of cerebral microcirculation in systemic thermal injury. J Burn Care Rehabil . 2000,Jan-Feb; 21(1 Pt 1):20-5.SCI
主编或副主编的著作/译著
重要奖项