宋育阳，女，1983年12月生，工学博士，副教授，硕士生导师
联系方式：yuyangsong@nwsuaf.edu.cn 电话：**
1.研究方向
葡萄酒生境下的酵母代谢；葡萄酒及果酒的工艺质量控制。
2. 教学工作
主要承担《葡萄与葡萄酒专业外语》、《葡萄酒工艺学》课程。主讲《葡萄酒工艺学》在中国大学生MOOC平台顺利上线。参与承担《葡萄酒微生物学》、《葡萄酒工艺学实验》、《葡萄酒后期管理》、《高级微生物学》、《葡萄酒学进展》等课程的教学。
3. 学习经历
(1) 博士，日本 北海道大学，2009.10--2013年3月，生物化学（工学）
(2) 硕士，西北农林科技大学，2006-2009年，发酵工程（葡萄与葡萄酒）
(3) 学士，西北农林科技大学，2002-2006年，酿酒工程（葡萄与葡萄酒）
4. 工作经历：
(1) 副教授，西北农林科技大学葡萄酒学院，2018-至今
(2)局长助理（挂职），宁夏回族自治区葡萄产业发展局，2018年
(3) 讲师，西北农林科技大学葡萄酒学院，2013-2018年
5.主要.科研项目
主持项目：
（1）国家重点研发计划子课题：智能化酿造技术及工艺创新，2019.5-2022.12
（2）西北农林科技大学试验示范站(基地)科技创新与成果转化项目：鲜食葡萄红地球酿造系列特种酒的技术集成与推广，2015.6-2017.5
（3）农业部葡萄酒加工重点实验室开放课题：本土优良戴尔有孢圆酵母的筛选及其产香机制研究， 2018.1-2019.12
（4）国家自然科学青年基金：葡萄酒生境下β-葡萄糖苷酶高效细胞表面展示研究，2016.1-2018.12
（5）教育部留学回国基金：西北葡萄酒产区乳酸菌生物多样性及其酿酒特性研究，2015.6-2017.6
（6）国际科技合作种子基金：新型耐热微生物利用可再生生物质生产工业乳酸，2016.7-2017.12
（7）陕西省专项配套经费：优选葡萄酿酒乳酸菌的酿酒特性研究，2015.9-2018.9
（8）西北农林科技大学试验示范站(基地)科技创新与成果转化项目：优选葡萄酿酒乳酸菌的酿酒特性研究及示范推广，2015.6-2017.5
（9）西北农林科技大学基本科研业务费专项资金项目：西北葡萄酒产区乳酸菌多样性及其酿酒特性研究，2014.1-2017.1
（10）西北农林科技大学博士启动基金：东北产区酿酒乳酸菌的多样性及其酿酒适应性研究，2014.1-2015.12
（11）内蒙汉森酒庄专项资金：内蒙汉森酒庄酿酒乳酸菌酿酒适应性研究，2013.01- 2014.12
6.发表论文
[1] Rong Huang, Fangfang Zhang, Xingmin Yan, Yi Qin, Jiao Jiang, Yanlin Liua, Yuyang Song*. Characterization of the β-Glucosidase Activity in indigenous yeast isolated from wine regions in China. Journal of Food Science. 2021, accepted.
[2] Lu, Y^#; Song, YY^#;Zhu, J; Xu, XG; Pang, B; Jin, H; Jiang, CM; Liu, YL; Shi, JL. Potential application of CHS and 4CL genes from grape endophytic fungus in production of naringenin and resveratrol and the improvement of polyphenol profiles and flavour of wine. 2020, DOI: 10.1016/j.foodchem.2020.128972.
[3] Zhang, Y; Min, Z; Qin, Y; Ye, DQ; Song, YY*; Liu, YL *. Efficient Display of Aspergillus niger beta-Glucosidase on Saccharomyces cerevisiae Cell Wall for Aroma Enhancement in Wine; Journal of Agricultural and Food Chemistry. 2019, 67(18): 5169-517.
[4] Feng L, Jia H, Wang JM, Qin Y, Liu YL*, Song YY*. Selection of Indigenous Saccharomyces cerevisiae Strains for Winemaking in Northwest China. American Journal of Enology and Viticulture, 2019, 70(2): 115-126.
[5] Song Yuyang, Zhang Yujie, Liu Ning, Ye Dongqing, Gong Xue, Qin Yi, Liu Yanlin*. Evaluation of volatiles of wild strawberry and impact odorants of strawberry wines at different stage of fermentation in southern Shaanxi, China. International Journal of Food Properties. 2017, 20:399-415
[6] Su BF, Xue JR, Xie CY, Fang YL, Song Yuyang*, Sigfredo F. Digital surface model applied to unmanned aerial vehicle based photogrammetry to assess potential biotic or abiotic effects on grapevine canopies. International Journal of Agricultural and Biological Engineering. 2016, 9(6):119-130.
[7] Liu Ning^#, Song YY^#, Dang Guofang, Ye Dongqing, Liu Yanlin*. Effect of Wine Closures on the Aroma Properties of Chardonnay Wines after Four Years of Storage. South African Journal of Enology and Viticulture. 2015, 3(36):296-303.
[8] Liu Ning, Qin Yi, Song Yuyang, Tao Yong Sheng, Sun Yue, Liu Yanlin*. Aroma composition and sensory quality of Cabernet Sauvignon wines fermented by indigenous S. cerevisiae strains in the eastern base of the Helan Mountain (China). International Journal of Food Properties, 2016, (19):2417-2431.
[9] Jiao Jian, Ma Yaner, Chen Sha, Liu Chonghuai, Song Yuyang, Qin Yi, Yuan Chunlong, Liu Yanlin*. Melatonin-Producing Endophytic Bacteria from Grapevine Roots Promote the Abiotic Stress-Induced Production of Endogenous Melatonin in Their Hosts. Frontiers in Plant Science, 2016, 7(3):1-13.
[10] Song Yuyang; John Masani Nduko; Ken’ichiro Matsumoto; Seiichi Taguchi. Corynebacterium glutamicum: From Systems Biology to Biotechnological Applications (Chapter: 9 Microbial factory for the production of polyesters: A new platform of Corynebacterium glutamicum) Caister Academic Press, 137-148, May 2015.
[11] Liu Ning, Qin Yi, Song Yuyang, Ye Dongqin, Yuan Wei, Pei Yingfang, Xue Bo, Liu Yanlin*.Selection of indigenous Saccharomyces cerevisiae strains in Shanshan County (Xinjiang, China) for winemaking and their aroma-producing characteristics. World Journal of Microbiology and Biotechnology, 2015, 31(11): 1781-1792.
[12] Liu Ning, Song Yuyang, Qin Yi, Gong xue, Liu Yanlin*. Chromatic Characteristics and Anthocyanin Compositions of Cabernet Sauvignon Wines: Influence of Indigenous Saccharomyces cerevisiae Strains in Ningxia, China. Food Science and Biotechnology, 2015, 24(6): 1973-1978.
[13] Ken’ichiro Matsumoto, Kota Tobitani, Shunsuke Aoki, Song Yuyang, Toshihiko Ooi, Seiichi Taguchi. Improved production of poly(lactic acid)-like polyester based on metabolite analysis to address the rate-limiting step. AMB Express 2014,4:83.
[14] Song Yuyang, Ken’ichiro Matsumoto, Tsutomu Tanaka, Akihiko Kondo, Seiichi Taguchi. Single-step production of polyhydroxybutyrate from starch by using α-amylase cell-surface displaying system of Corynebacterium glutamicum. J. Biosci. Bioeng. 2013, 115(1), 12-14.
[15] Ken’ichiro Matsumoto, Satsuki Terai, Ayako Ishiyama, Jian Sun, Taizo Kabe, Song Yuyang, John Masani Nduko, Tadahisa Iwata, Seiichi Taguchi. One-pot microbial production, mechanical properties, and enzymatic degradation of isotactic P[(R)-2-hydroxybutyrate] and its copolymer with (R)-lactate. Biomacromolecules. 2013,14(6):1913-1918.
[16] Song Yuyang, Ken’ichiro Matsumoto, Miwa Yamada, Aoi Gohda, Christopher J. Brigham, Anthony J. Sinskey, Seiichi Taguchi. Engineered Corynebacterium glutamicum as an endotoxin-free platform strain for lactate-based polyester production. Appl Microbiol Biotechnol 2012, 93,1917–1925.
[17] Ken’ichiro Matsumoto, KeiKitagawa, Sung-JinJo, Song Yuyang, SeiichiTaguchi. Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) in recombinant Corynebacterium glutamicum using propionate as a precursor. J. Biotechnol 2011, 152, 144-146.
[18] Fumi Shozui, Jian Sun, Song Yuyang, Miwa Yamada, Kohei Sakai, Ken’ichiro Matsumoto, Kazuma Takase, Seiichi Taguchi. A new beneficial mutation in pseudomonas sp. 61-3 polyhydroxyalkanoate (PHA) synthase for enhanced cellular content of 3-hydroxybutyrate-based PHA explored using its enzyme homolog as a mutation template. Biosci Biotechnol Biochem 2010, 74, (8), 1710-1712.
[19]黄蓉, 董超, 余鸿飞, 秦义, 刘延琳, 宋育阳*. 利用酿酒酵母表面展示技术表达酸性蛋白酶的研究.中国食品学报, 2020, 已接收.
[20] 杨诗妮, 叶冬青, 贾红帅, 张文静, 宋育阳, 刘延琳. 本土戴尔有孢圆酵母在葡萄酒酿造中的应用潜力[J]. 食品科学, 2019, 40(18): 108-115.
[21]郝爱玲, 冯莉, 秦义, 宋育阳, 刘延琳. 降解柠檬酸酵母菌的筛选及其发酵性能研究[J].中国食品学报, 2018, 18(11): 72-80.
[22]张玉洁, 宋育阳, 秦义*, 刘延琳*. CRISPR-Cas 系统在食品微生物中的应用研究进展. 食品科学, 2017, 38(11): 269-275.
[23]张玉洁, 李莹, 秦义, 宋育阳, 刘延琳. 丝氨酸对葡萄酒酿造过程中酿酒酵母产H₂S的形成研究, 中国酿造, 2017, 36(06):121-125.
[24]李丽, 冯莉, 秦义, 叶冬青, 宋育阳*, 刘延琳*. 野生嗜杀白假丝酵母LFA418的产毒条件优化及其毒素粗提物特性, 食品科学, 2017,38(12): 50-56.
[25]袁琳, 宋育阳*, 周越, 刘延琳. 不同酿酒酵母发酵对赤霞珠葡萄酒颜色的影响[J]. 山西农业大学学报(自然科学版), 2017, 37(7):528-532.
[27]白稳红, 黄小晶, 秦义, 宋育阳, 刘延琳*.宁夏甘城子小产区梅鹿辄葡萄酒品质提升的研究, 中国酿造, 2016, (10):41-45.
[28]袁琳, 宋育阳*, 鲁燕汶,等. 两种酵母菌对猕猴桃原酒品质的影响, 山西农业大学学报,自然科学版, 2017, 37(2):130-133.
[29]宋育阳, 刘延琳. 宁夏神索葡萄自然发酵酵母菌群研究, 华中农业大学学报, 2010, 29（2）:71-75.
[30]宋育阳, 裴颖芳, 刘延琳. 蛇龙珠自然发酵过程酵母菌的种类和动态变化, 酿酒科技, 2009, 7:33-35.
[31]宋育阳, 裴颖芳, 王国平, 刘延琳. 黑比诺葡萄接种发酵过程酵母菌的变化监控, 中国食品学报, 2010, 10（2）：125-130.
[32]孙悦, 宋育阳, 刘延琳. 梅鹿辄葡萄自然发酵酵母菌群研究, 中国酿造, 2011, 9:27-29.
[33]王国平, 宋育阳, 裴颖芳, 刘延琳.宁夏御马葡萄酒厂野生酵母菌株的分离筛选及分子鉴定, 中国酿造, 2009, 8:38-41.
7.会议论文
1.Song YY, Matsumoto K, Yamada M, Gohda A, Taguchi S. A novel microbial production system for lactate-based polyester. Paper No: PBi-21, The 5th GCOE International Symposium, Hokkaido University, Sapporo, 2012.02, 口头报告.
2.Song YY, Matsumoto K, Yamada M, Gohda A, J. Brigham C, J. Sinskey A, Taguchi S. Direct conversion of glucose into lactate-based polyesters using engineered Corynebacterium glutamicum as a whole cell catalyst. Paper No: BIOT308, 243rd ACS National Meeting, San Diego, USA, 2012.03, 口头报告.
3.Song YY, Matsumoto K, Yamada M, Taguchi S. Engineered Corynebacterium glutamicum as an endotoxin-free platform for lactate-based polyester production. Paper No: AB1-08, The 12th Japan-China-Korea Joint Symposium on Enzyme Engineering, Kanazawa, 2012.05, 口头报告.
4.Song YY, Matsumoto K, Yamada M, Taguchi S. Biosynthesis of lactate-based polyesters in metabolically engineered Corynebacterium glutamicum . Paper No: O-S2-0061, 15th International Biotechnology Symposium and Exhibition, Daegu, Korea, 2012.09, 口头报告.
5.Song YY, Matsumoto K, Yamada M, Gohda A, Taguchi S. Biosynthesis of lactate-based polyester in food-grade bacterium. Paper No: No.P31, 高分子学会北海道支部研究発表会, 札幌, 2012.01, 口头报告.
6.Song YY, Matsumoto K, Yamada M, Taguchi S. Biosynthesis of lactate-based polyester using engineered Corynebacterium glutamicum as a whole cell catalyst. International Symposium on Biopolymers, Cairns, Australia, 2012.10, 口头报告.
7.Song YY, Gohda A, Matsumoto K, Yamada M, Taguchi S. Production of poly(lactate-co-3-hydroxybutyrate) in recombinant Corynebacterium glutamicum expressing lactate-polymerizing enzyme. Paper No: IN-26, 2011 Taiwan-Japan Bilateral Polymer Symposium, Taiwan, 2011.09, 口头报告.
8.Song YY, Gohda A, Matsumoto K, Yamada M, Taguchi S. Biosynthesis of poly(lactate-co-3-hydroxybutyrate) in endotoxin-free Corynebacterium glutamicum expressing lactate-polymerizing enzyme. Paper No: No.2Ka02, 日本生物工学会大会, 東京, 2011.09, 口头报告.
9.Song YY, Gohda A, Matsumoto K, Yamada M, Taguchi S. Production of endotoxin-free lactate(LA)-based polyesters in recombinant Corynebacterium glutamicum. Paper No: 2C01p14 日本農芸化学会大会, 京都, 2011.03, 口头报告.
10.Song YY, Matsumoto K, Taguchi S. Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) in recombinant Corynebacterium glutamicumusing propionate as a precursor. Paper No: 11, 平成22年度第一回合同学術講演会, Sapporo, 2010.07, 口头报告.
11.Nduko J M, Matsumoto K, Song YY, Taguchi S. Microbial plastic factory: synthesis and properties of the new lactate-based and related biopolymers. Paper No: POLY72, 244th ACS National Meeting & Exposition, Philadelphia, USA, 2012.08, 口头报告.
12.津田春奈, 宋育陽, 松本謙一郎, 大井俊彦, 近藤昭彦, 田口精一. Corynebacterium glutamicum の細胞表層提示技術を用いたデンプンからのポリヒドロキシブタン酸(PHB)の直接生産. Paper No: 2C01p05, 日本農芸化学会大会, 京都, 2012.03,
13.渡辺剛志, 宋育陽, 松本謙一郎, 大井俊彦, 田口精一. アセトアセチルCoAレダクターゼ高活性変異体の解析とそれを用いたCorynebacterium glutamicumによるPHB生産の増強. Paper No: 2C01p06, 日本農芸化学会大会, 京都, 2012.03,
14.Watanabe T, Song YY, Matsumoto K, Ooi T, Taguchi S. Enhanced polyhydroxybutyrate production by highly active mutant of acetoacetyl-CoA reductase in Corynebacterium glutamicum. Paper No: PBi-09, The 5th GCOE International Symposium, Hokkaido University, Sapporo, 2012.02, 口头报告.