教育背景
博士：1996.9-2000.7；华中农业大学；生物化学与分子生物学
硕士：1989.9-1992.7；中国科学院武汉病毒研究所；病毒学
学士：1985.9-1989.7；山东师范大学；普通生物学
工作经历
起止时间 单位名称 专业技术职务
2009.3-至今 山东大学 教授
2004.3-2009.12 University of Texas Health Science Center at Tyler (USA)
Instructor, Research associate senior, Post-doc.
2001.5-2004.2 University of Nancy I (France), Post-doc.
研究方向
1.放线菌的代谢调控
2.微生物的生物降解及环境的生物修复
3. 海洋细菌的酶及生物学


科研项目
1，国家重点研发计划（2018YFC**），主持（子课题）
2，国家重点研发计划（2016YFA**），主持（子课题）
3，国家自然科学基金应急项目（**），主持
4，国家自然科学基金面上项目（**），主持
5，国家自然科学基金面上项目（**），主持
6，国家自然科学基金面上项目（**），主持
7，山东省自然科学基金面上项目（ZR2019MC062），主持
8，山东省自然科学基金面上项目（ZR2010HM007），主持


代表性论文
*:通讯作者
★Zhu Y,Zhang P,Zhang J,Lu Y,andPang X*. The pleiotropic regulator MtrA has a role in phosphate metabolismcontrol inStreptomyces coelicolor.
★Zhu Y,Lu T, Zhang J, Tao M, andPang X*. 2020.A novel XRE-family regulator that controls antibiotic production and development inStreptomyces coelicolor. Applied Microbiology and Biotechnology.
★Zhu Y,Zhang P,Zhang J,Wang J,Lu Y,andPang X*. 2020. Impact on multiple antibiotic pathways reveals MtrA as a master regulator of antibiotic production inStreptomycesand potentially in other actinobacteria.Applied andEnvironmentalMicrobiology 86 (20): e01201-20(Genetics and Molecular Biology Section)
★Zhu Y,Xu W, ZhangP,Zhao Z, Sheng D, Ma W, Zhang YZ, Bai L, andPang X*. 2020.A hierarchical network of four regulatory genes controls production of the polyene antibiotic Candicidin inStreptomycessp. FR-008.Applied andEnvironmentalMicrobiology 86(9): e00055-20 (Genetics and Molecular Biology Section).
★Zhu Y, Zhang P, Zhang J, Xu W, Wang X, Wu L, Sheng D, Ma W, Cao G, Chen X, Lu Y, Zhang Y, and Pang X*. 2019. The developmental regulator MtrA binds GlnR boxes and represses nitrogen metabolism genes inStreptomyces coelicolor.Molecular Microbiology 112 (1):29-46.
★ Liu M, Zhang P, Zhu Y, Lu T, Wang Y, Cao, G, Shi M, Chen X, Tao M, andPang X*.2019.Novel Two-Component system MacRS is a pleiotropic regulator that controls multiple morphogenic membrane protein genes inStreptomyces coelicolor.Applied and Environmental Microbiology 85 (4): e02178-18(Genetics and Molecular Biology Section).
★ Lu T, Zhu Y, Zhang P, Sheng D, Cao G,Pang X*. 2018. SCO5351 is a pleiotropic factor that impacts secondary metabolism and morphological development inStreptomyces coelicolor.FEMS Microbiology Letter 365 (17), fny150.
★ Zhang P, Wu L, Zhu Y, Liu M, Wang Y, Cao G, Chen XL, Tao M,Pang X*. 2017. Deletion of MtrA inhibits cellular development ofStreptomyces coelicolorand alters expression of developmental regulatory genes.Frontiers in Microbiology8:2013(1-18).
★ Zhao Z, Shi T, Xu M, Brock NL, Zhao YL, Wang Y, Deng Z,Pang X*, Tao M*. 2016. Hybrubins: Bipyrrole tetramic acids obtained by crosstalk between a truncated undecylprodigiosin pathway and heterologous tetramic acid biosynthetic genes.OrganicLETTERS 18(3):572-5.
★ Cao G, Howard ST, Zhang P, Wang X, Chen XL, Samten B, and Pang X*. 2015.EspR, a regulator of the ESX-1 secretion system inMycobacterium tuberculosis,is directly regulated by the two-component systemsMprAB and PhoPR.Microbiology 161(3):477-489.
★ Zhang P, Zhao Z, Li H, Chen XL, Deng Z, Bai L, and Pang X*. 2015. Production of the antibiotic FR-008/Candicidin inStreptomycessp. FR-008 is coregulated by two regulators, FscRI and FscRIV, from different transcription factor families.Microbiology161(3):539-552.
★ Zhang P, Wu H, Chen XL, Deng Z, Bai L, and Pang X*. 2014. Regulation of the Biosynthesis of Thiopeptide Antibiotic Cyclothiazomycin by a Transcriptiona1 Regulator SHJG8833 inStreptomyces hygroscopicus5008.Microbiology 160 (7):1379-1392.
★Pang X*, Samten B, Cao G, Wang X, Tvinnereim A, Chen X, and Howard ST. 2013. MprAB regulates theespAoperon inMycobacterium tuberculosis, and modulates ESX-1 function and host cytokine response.Journal of Bacteriology 195(1):66-75.
★Pang X, Howard ST. 2007. Regulation of the alpha-crystallin gene acr2 by the MprAB two-component system ofMycobacterium tuberculosis.Journal of Bacteriology 189(17):6213-21.
★Pang X, Vu P, Byrd TF, Ghanny S, Soteropoulos P, Mukamolova GV, Wu S, Samten B, Howard ST. 2007. Evidence for complex interactions of stress-associated regulons in an mprAB deletion mutant ofMycobacterium tuberculosis.Microbiology153(4):1229-42.
★ Aigle B?,Pang X?, Decaris B, Leblond P. 2005. Involvement of AlpV, a new member of the Streptomyces antibiotic regulatory protein family, in regulation of the dupliated type II polyketide synthase alp gene cluster inStreptomyces ambofaciens.Journal of Bacteriology 187(7):2491-500.
★Pang X, Aigle B, Girardet JM, Mangenot S, Pernodet JL, Decaris B, Leblond P. 2004. Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of theStreptomyces ambofacienslinear chromosome.Antimicrobial Agents and Chemotherapy 48(2):575-88.
★Pang X, Zhou X, Sun Y, Deng Z. 2002.Physical map of the linear chromosome ofStreptomyces hygroscopicus10-22 deduced by analysis of overlapping large chromosomal deletions.Journal of Bacteriology 184(7):1958-65.