一、基本情况
李孝训，山东大学齐鲁青年********，药物化学专业博士生导师。2017年入选“山东大学齐鲁青年****”。近五年，先后参与完成美国NIH科研基金课题2项，完成美国NSF科研基金课题1项，已在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Chem. Sci. 等国际著名刊物上发表论文二十余篇，获得美国授权专利2项。
通讯地址：山东省济南市文化西路44号山东大学药学院药物化学研究所
TEL:
Emai: xli@sdu.edu.cn

二．研究领域
1. 基于靶点结构的药物活性小分子的设计、合成及生物活性研究；
2. 具有重要生理活性的复杂天然产物的全合成及构效关系研究。

三．工作及学习经历
2003.9 – 2007.7 天津大学药学院，本科；
2007.9 – 2009.7 天津大学药学院，硕士；
2009.7－2014.12 美国威斯康星大学麦迪逊分校（UniversityofWisconsin-Madison）药学院，博士；
2015.3 – 2017.6 美国斯坦福大学(StanfordUniversity)化学系，博士后；
2017.12-至今 山东大学药学院药物化学研究所教授、博士生导师。
四、教学工作
承担本科生《有机化学》，《有机化学实验》，研究生《高等有机化学》等课程的教学。
五．承担课题
山东大学齐鲁青年****启动基金，2017年


六．代表性学术论文（限10篇）
1.Barry M. Trost*, Xiaoxun Li. “Palladium Catalyzed Asymmetric Allylic Alkylations via C-H Activation of N-allyl Imines and Glycinates”Chem. Sci.2017, 8, 6815-6821.
2.Xiaoxun Li, Hui Li, Wangze Song, Po-Sen Tseng, Lingyan Liu, Ilia A. Guzei, Weiping Tang* “Divergent Reactivity of Rhodium (I) Carbenes Derived from Indole Annulations” Angew. Chem. Int. Ed.2015, 54, 12905-12908.
3.Xiaoxun Li, Wangze Song, and Weiping Tang* “Rhodium-catalyzed Tandem Annulation and [5+1] Cycloaddition: 3-Hydroxy -1,4-enyne as the 5-Carbon component” J. Am. Chem. Soc., 2013, 135, 16797-16800.
4.Xiaoxun Li, Min Zhang, Dongxu Shu, Patrick J. Robichaux, Suyu Huang, and Weiping Tang* “Rhodium-catalyzed Ring Expansion of Cyclopropanes to Seven-membered Rings by 1,5-C-C Bond Migration” Angew. Chem. Int. Ed., 2011, 50, 10421-10424.
5.Xiaoxun Li, Haibo Xie, Xiaoning Fu, Jitian Liu, Haoyuan Wang, Baomin Xi, Xiufang Xu, Peng Liu, Weiping Tang* “Rhodium(I)-catalyzed Benzannulation of Heteroaryl Propargylic Esters: Synthesis of Indoles and Related Heterocycles” Chem. Eur. J.2016, 22, 10410-10414.
6.Xiaoxun Li, Wangze Song, Xiaona Ke, Xiufang Xu, Peng Liu, K. N. Houk, Xian-liang Zhao, Weiping Tang* “Rhodium-catalyzed Intramolecular [5+2] Cycloaddition of Inverted 3-Acyloxy-1,4-enyne and Alkyne: Experimental and Theoretical Studies” Chem. Eur. J.2016, 22,7079 –7083.
7.Xiaoxun Li, Suyu Huang, Casi M. Schienebeck, Dongxu Shu, and Weiping Tang* “Rhodium-Catalyzed Carbonylation of 3-Acyloxy-1,4-enynes for the Synthesis of Cyclopentenones” Org. Lett., 2012, 14, 1584-1587.
8.Xiaoxun Li, Yunfei Du*, Zhidan Liang, Xiangke Li, Yan Panand Kang Zhao*“Simple Conversion of Enamines to 2H-Azirines and Their Rearrangements under Thermal Conditions” Org. Lett., 2009,11, 2643-2646.
9.Xing-zhong Shu, Xiaoxun Li, Dongxu Shu, Suyu Huang, Casi M. Schienebeck, Xin Zhou, Patrick J. Robichaux, and Weiping Tang* “Rhodium-catalyzed Intra- and Intermolecular [5+2] Cycloaddition of 3-Acyloxy-1,4-enyne and Alkyne with Concomitant 1,2-Acyloxy Migration” J. Am. Chem. Soc., 2012, 134, 5211-5221.
10.Dongxu Shu, Xiaoxun Li, Min Zhang, Patrick J. Robichaux, and Weiping Tang* “Synthesis of Highly Functionalized Cyclohexenone Rings: Rhodium-Catalyzed 1,3-Acyloxy Migration and Subsequent [5+1] Cycloaddition” Angew. Chem. Int. Ed.2011, 50, 1346-1349.