宁利敏^1,2, 朱玉翠³, 于光^1,2, 曹声生⁴, 朱本伟⁴, 姜帅⁵, 周明柱⁵
1.南京中医药大学医学院·2.整合医学院, 江苏 南京 210023;3.山东省曲阜市吴村镇人民政府, 山东 曲阜 273100;4.南京工业大学食品与轻工学院, 江苏 南京 211816;5.宿迁市南京工业大学新材料研究院, 江苏 宿迁 223800

摘要:
海洋来源的功能寡糖具有多种生物活性，如抗炎、抗氧化、抗病毒、抗肿瘤和免疫调节等，因此在医药、农业、化工及环境等领域有着广泛的应用。然而，不同聚合度、不同结构的寡糖所具有的活性差异很大，因此有必要深入研究和探讨不同种类的海洋功能寡糖的结构与功能的关系及其应用潜力。本文对几种研究较多的海藻功能寡糖的来源、制备、纯化及应用进行了系统总结，为推动海藻功能寡糖的开发应用研究奠定良好的理论基础。
关键词:海藻功能寡糖结构制备活性与应用
DOI：10.11759/hykx20200616004
分类号:P745
基金项目:宿迁市科技计划项目（L201906），国家自然科学基金项目（31601410）

Recent advances in the structure, preparation, activity, and application of several marine seaweed functional oligosaccharides
NING Li-min^1,2, ZHU Yu-cui³, YU Guang^1,2, CAO Sheng-sheng⁴, ZHU Ben-wei⁴, JIANG Shuai⁵, ZHOU Ming-zhu⁵
1.School of Medicine &2.Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China;3.People's government of Wucun Town, Qufu 273100, China;4.College of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China;5.Suqian Advanced Materials Institute, Nanjing Tech University, Suqian 223800, China
Abstract:
Marine functional oligosaccharides are widely used in the food, agricultural, and medical fields owing to their physiological properties such as anti-oxidant, anti-inflammatory, anti-tumor, anti-virus, and immune-regulatory activities. However, based on the extent of polymerization, the resultant physiological properties of these oligosaccharides greatly differ. Therefore, it is essential to investigate the relationship between the structure and function and the potential of these marine functional oligosaccharides for better application. This review summarizes the recent advances in the molecular structure, preparation, and physiological activities of several types of marine seaweed oligosaccharides toward promoting the utilization and development of marine functional oligosaccharides in the future.
Key words:marine seaweed functional oligosaccharidesstructurepreparationactivityapplication





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