姓名：张全启
学历/职称/职务：博士/教授
联系方式：
邮箱：qzhang@ouc.edu.c电话：
地址：青岛市鱼山路5号
学习工作简历：
1979.9-1983.7：中国海洋大学（原山东海洋学院）海洋生命学院，获理学学士学位。
1983.9-1986.7：中国海洋大学海洋生命学院，获理学硕士学位。
1986.7-1994.2：中国海洋大学海洋生命学院，助教、讲师。
1994.10-1998.2：日本广岛大学生物生产学部，获哲学博士学位。
1998.3-1999.2：美国威廉马丽大学海洋研究所，博士后。
1999.3-2001.2：日本水产养殖研究所，科技厅特别研究员（博士后）。
1999.12—现在：中国海洋大学海洋生命学院教授、博士生导师。其中，
2003.10-2011.7期间，任中国海洋大学海洋生命学院院长。
科研领域描述：
多年来，一直从事海洋生物遗传学和基因组学研究，主要研究内容包括：（1）鱼类分子遗传学及优良品种选育；（2）鱼类染色体组操作与性别决定机制；（3）鱼类基因组学和功能基因研究；（4）鱼类胚胎干细胞、生殖干细胞分离培养、移植及借腹生子研究。
（1）在我国率先建立了星鲽和石鲽的生殖调控人工繁殖技术体系，实现了星鲽和石鲽的人工繁殖，使我国鲽类人工繁殖技术达到国际先进水平。（2）率先开展半滑舌鳎基因组学研究，分析了半滑舌鳎基因组特征；建立了鱼类染色体显微切割技术、性别鉴定技术、性别控制育种技术等，在国内外同领域产生重要影响。（3）开展了牙鲆分子和细胞遗传学研究，建立了牙鲆优良品种培育体系。（4）开展了鲆鲽鱼类胚胎干细胞和生殖干细胞研究，分离鉴定了一批胚胎干细胞和生殖干细胞特异表达的基因，构建了干细胞特异表达的GFP识别载体，并成功地识别了胚胎干细胞和生殖干细胞，为进一步开展鱼类借腹生子研究奠定了基础。（5）近年来承担完成国家级、省部级课题数十项；发表论文80余篇，其中SCI收录60余篇；获专利6项，国家知识产权2项，获省部级奖励4项。

代表性成果：
代表性论文
1.QiwangZhong,QuanqiZhang*,YanjieChena,YeyingSuna,JieQia,ZhigangWanga,ShuoLia,ChunmeiLiaandXunLan.2008.TheisolationandcharacterizationofmyostatingeneinJapaneseflounder(Paralichthysolivaceus):Ubiquitoustissueexpressionanddevelopmentalspecificregulation.Aquaculture,281(1-4):247-255.
2.QiwangZhong,QuanqiZhang*,ZhigangWang,JieQi,YanjieChen,ShuoLi,YeyingSun,ChunmeiLi,XunLan,2008.ExpressionProfilingandValidationofPotentialReferenceGenesDuringParalichthysolivaceusEmbryogenesis.MarineBiotechnology.10(3):310-318.
3.XuboWang,QuanqiZhang*,XiaohuaSun,YanjieChen,TengZhai,WeiZhuang,JieQiandZhigangWang.2009.FosmidLibraryConstructionandInitialAnalysisofEndSequencesinFemaleHalf-smoothTongueSole(Cynoglossussemilaevis)MarineBiotechnology,11(2):236-242.
4.YanYu,QiwangZhong,ChunmeiLi,LimingJiang;FushengYan;ZhigangWang;QuanqiZhang*,2009.IsolationandcharacterizationofToll-likereceptor9inhalf-smoothtongue soleCynoglossussemilaevis.FishandShellfishImmunology.26：492-499.
5.JianpengXu,QuanqiZhang*,XiaofeiXu,ZhigangWang,JieQi.2009.IntragenomicVariabilityandPseudogenesofRibosomalDNAinStoneFlounderKareiusbicoloratus.MolecularPhylogeneticsandEvolution52(2009)157-166.
6.YanYu,QiwangZhong,ChunmeiLi,LimingJiang;FushengYan;ZhigangWang;QuanqiZhang*,2009.Full-lengthsequenceandexpressionanalysisofamyeloiddifferentiationfactor88(MyD88)inhalf-smoothtonguesoleCynoglossussemilaevis.InternationalJournalofImmunogenetics.36:173–182.
7.XuboWang,QuanqiZhang*,JianRen,ZhanjunJiang,ChangmengWang,WeiZhuang,TengZhai,2009.Thepreparationofsex-chromosome-specificpaintingprobesandconstructionofsexchromosomeDNAlibraryinhalf-smoothtonguesole(Cynoglossussemilaevis).Aquaculture,297:78-84.
8.WANGXubo,ZHANGQuanqi*,CHENYanjie,QIJie,WANGZhigang,WANGXinglian,2009.CytogeneticcharacterizationofoliveflounderParalichthysolivaceus:DNAcontent,karyotype,AgNORsandlocationofmajorribosomalgenes.ActaOceanologicaSinica,28(4):72-77.
9.YeyingSun,HaiyangYu,QuanqiZhang*,JieQi,QiwangZhong,YanjieChen,ChunmeiLi.2010.Molecularcharacterizationandexpressionpatternoftwozonapellucidagenesinhalf-smoothtonguesole(Cynoglossussemilaevis).ComparativeBiochemistryandPhysiology,PartB.155(2010)316–321.
10.YeyingSun,QuanqiZhang*,JieQi,YanjieChen,QiwangZhong,YanYu,ShuoLi,ZhigangWang,ChunmeiLi.2010.Identificationofdifferentialgenesintheovaryrelativetothetestisandtheirexpressionpatternsinhalf-smoothtonguesole(Cynoglossussemilaevis).J.Genet.Genomomics,37(2):137-145.
11.YudingFan,ShuoLi,JieQi,LingbingZeng,QiwangZhong,QuanqiZhang*.2010.CloningandcharacterizationoftypeIIInterleukin-1receptorcDNAfromJapaneseflounder(Paralichthysolivaceus).ComparativeBiochemistryandPhysiology,PartB.157:59–65.
12.QuanqiZhang*,HaiyangYu,AimeeHowe,WhitneyChandler&StandishK.AllenJr.2010.CytogeneticmechanismforreversionoftriploidstoheteroploidmosaicsinCrassostreagigas(Thunberg)andCrassostreaariakensis.AquacultureResearch,41,1658-1667.
13.QuanqiZhang*,YanZhuangandStandishK.Allen.2010.MeioticchromosomeconfigurationsintriploidandheteroploidmosaicmalesofCrassostreagigasandCrassostrea.ariakensis.AquacultureResearch,41,1699-1706.
14.Li,?C.,Yu,?Y.,Sun,?Y.,Li,?S.,Zhong,?Q.,Wang,?X.,Wang,?Z.,Qi,?J.,Zhang,?Q*.2010.Isolation,polymorphismandexpressionstudyoftwodistinctmajorhistocompatibilitycomplexclassIIBgenesfromhalf-smoothtonguesole(Cynoglossussemilaevis).Intern.J.Immunogenet.37(3):185-197.
15.Chunmei?Li,Quanqi?Zhang*,Yan?Yu,Shuo?Li,Qiwang?Zhong,Yeying?Sun,Zhigang?Wang,Jie?Qi,Jieming?ZhaiandXubo?Wang.2011.Sequencepolymorphismoftwomajorhistocompatibility(MH)classIIBgenesandtheirassociationwithVibrioanguillaruminfectioninhalf-smoothtonguesole(Cynoglossussemilaevis).ChineseJournalofOceanologyandLimnology,29(6):1275-1286.
16.YuH,HeY,WangX,ZhangQ,BaoZ,GuoX.2011.Polymorphisminaserineproteaseinhibitorgeneanditsassociationwithdiseaseresistanceintheeasternoyster(CrassostreavirginicaGmelin).FishShellfishImmunol.30(3):757-62.
17.YanYu,QiwangZhong,ChunmeiLi,LimingJiang,YananWang,YeyingSun,XuboWang,ZhigangWang,QuanqiZhang*.2012.IdentificationandcharacterizationofIL-1receptor-associatedkinase-4(IRAK-4)inhalf-smoothtonguesoleCynoglossussemilaevis.FishandShellfishImmunology.32(4):609-15.
18.HeY,YuH,BaoZ,ZhangQ,GuoX.2012.MutationinpromoterregionofaserineproteaseinhibitorconfersPerkinsusmarinusresistanceintheeasternoyster(Crassostreavirginica).FishShellfishImmunol.33(2):411-7.
19.WangXubo,Jiajun?Jiang,Jinning?Gao,Jinxiang?Liu,Jie?Qi,Zhigang?Wang,Haiyang?Yu,Quanqi?Zhang,2013.Identificationoftwonovelfemale-specificDNAsequencesinhalf-smoothtonguesole,Cynoglossussemilaevis.Aquaculture,388-391:49-53.
20.LimingJiang,GuannanChu,QuanqiZhang,ZhigangWang,XuboWang,JiemingZhai,HaiyangYu,2013.Amicrosatellitegeneticlinkagemapofhalfsmoothtonguesole(Cynoglossussemilaevis).MarineGenomics,9:17-23.
21.J.Jiang,C.Li,Q.Zhang,andX.Wang.2013.CloningandcharacterizationofmajorhistocompatibilitycomplexclassIIgenesinthestoneflounderKareiusbicoloratus(Pleuronectidae).GeneticsandMolecularResearch.12(4):5820-5832.
22.MaLiman,WangWenji,LiuConghui,YuHaiyang,WangZhigang,WangXubo,QiJie,ZhangQuanqi.2013.Selectionofreferencegenesforreversetranscriptionquantitativereal-timePCRnormalizationinblackrockfish(Sebastesschlegeli).MarineGenomics.11:67-73.
23.JinningGao,JingWang,JiajunJiang,LinFan,WenjiWang,JinxiangLiu,QuanqiZhang*,XuboWang.2013.IdentificationandcharacterizationofananoghomologinJapaneseflounder(Paralichthysolivaceus).Gene.531(2):411-421.
24.XiaomengWu,ZhongkaiWang,JiajunJiang,JinningGao,JingWang,XiaosuZhou,QuanqiZhang.2014.Cloning,expressionandpromoteranalysisofvasageneinJapaneseflounder(Paralichthysolivaceus).ComparativeBiochemistryandPhysiology,PartB167:41-50.
25.ZhengRuiZhang,XinglianWang,QuanqiZhangandStandishK.Allen.Jr.2014.CytogeneticmechanismsontheaneuploidyandmosaicismintetraploidPacificoystersCrassostreagigas(Thunberg)producedfromeggsoftriploids.J.OceanUniv.China,13(1):125-131.
26.ZhengRuiZhang,XinglianWang,QuanqiZhangandStandishK.Allen.Jr.2013.PreferentialbivalentformationintetraploidmalesofPacificoystersCrassostreagigas(Thunberg).J.OceanUniv.China,13(2):297-302.
27.ZhongkaiWang,JinningGao,HuayuSong,XiaomengWu,YanSun,JieQi,HaiyangYu,ZhigangWang,QuanqiZhang.2014.Sexuallydimorphicexpressionofvasaisoformsinthetonguesole(Cynoglossussemilaevis).PLOSONE,9(3):e93380.
28.ConghuiLiu,NianXin,YiZhai,LimingJiang,JiemingZhai,QuanqiZhang,JieQi.2014.ReferenceGeneSelectionforQuantitativeReal-TimeRT-PCRNormalizationintheHalf-SmoothTongueSole(Cynoglossussemilaevis)atDifferentDevelopmentalStages,inVariousTissueTypesandonExposuretoChemicals.PLOSONE,9(3):e91715.
专利、著作权
1.王旭波，张全启，齐洁，王志刚，于海洋，**。一种激光纤维切割染色体标本制作液及其应用，ZL8.8
2.王亚楠，张全启，刘旭东，王旭波，齐洁，于海洋，王兴莲，**。半滑舌鳎hepcidin抗菌肽，ZL6.2
3.王亚楠，张全启，刘旭东，王旭波，齐洁，于海洋，王兴莲，**。半滑舌鳎抗菌肽hepcidin的重组表达及其应用，ZL8.3
4.王旭波，张全启，高金宁，姜佳君，齐洁，王志刚，于海洋，**。荧光原位杂交技术检测半滑舌鳎的行染色体组成的方法，ZL6.4
杨俊杰，张全启，2009。鲽型目分类信息分析系统，2009SR02219