导师姓名： 曾乃燕 专业代码： 100100
性别： 女 专业名称： 基础医学
培养单位： 基础医学院 三级学科/
专业领域：
导师类型： 硕士生导师 专业学位导师：
联系方式： Tel: ext 776909zengny@shsmu.edu.cn
邮编： 200025 邮箱地址： zengnaiyan@gmail.com

研究方向 (点击浏览详细信息)
肿瘤分子靶标与临床转化医学

社会任职
国家自然科学基金 评审专家
上海市病理生理学会 会员
Biochemistry and Molecular Biology 编委
中国临床肿瘤协会（SCCO）会员
中国病理学会 会员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 淋巴瘤中ABIN 家族基因表达和基因突变分析及其突变体的功能研究 自然科学基金 面上项目 2014-01~2017-12 73万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Liu F,ZhengJ-P, Wang L, Zhao D-H, Li M-Y, Wang Y-M, Liu Y, Ma J, Zeng N-Y, Liu H-X, Liang R, Guo S-P, Wang Z, and Yan Q-G, Activation of the NF-κB Pathway and Heterozygous Deletion of TNFAIP3 (A20) Confer Superior Survival in Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type. American Journal of Clinical Pathology 2019 152(2):243-252
Wu J, Zhang W, Xia L, Feng L, Shu L, Zhang J, Ye W, Zeng N （通讯作者）, Zhou A. Characterization of PPIB interaction in the P3H1 ternary complex and implications for its pathological mutations. Cell Mol Life Sci 2019 eprint
邱泽平,张晶,杨迟晖,曾乃燕 （通讯作者） 液体活检在结直肠癌中的应用进展 医学综述 2018 24（11）：2129-2134
Wei H, Cai H, Jin Y, Wang P, Zhang Q, Lin Y, Wang W, Cheng J, Zeng N （通讯作者）, Xu T, Zhou A Structural basis of a novel heterodimeric Fc for bispecific antibody production Oncotarget 2017 8(31): 51037-51049
Zhang F, Qi X, Wang X, Wei D, Wu J, Feng L, Cai H, Wang Y, Zeng N, Xu T, Zhou A, Zheng Y. Structural basis of the therapeutic anti-PD-L1 antibody atezolizumab Oncotarget 2017 8(52):90215-90224
Moody S, Escudero-Ibarz L, Wang M, Clipson A, Ochoa Ruiz E, Dunn-Walters D, Xue X, Zeng N, Robson A, Chuang SS, Cogliatti S, Liu H, Goodlad J, Ashton-Key M, Raderer M, Bi Y, Du MQ Significant association between TNFAIP3 inactivation and biased immunoglobulin heavy chain variable region 4-34 usage in mucosa-associated lymphoid tissue lymphoma J Pathol 2017 243(1): 3-8.
Wang M, Escudero-Ibarz L, Moody S, Zeng N, Clipson A, Huang Y, Xue X, Grigoropoulos NF, Barrans S, Worrillow L, Forshew T, Su J, Firth A, Martin H, Jack A, Brugger K, Du MQ. Somatic Mutation Screening Using Archival Formalin-Fixed, Paraffin-Embedded Tissues by Fluidigm Multiplex PCR and Illumina Sequencing J Mol Diagn. 2015 17(5):521-32.
Chang Q, Zhang L, He C, Zhang B, Zhang J, Liu B, Zeng N （通讯作者）, Zhu Z HOXB9 induction of mesenchymal-to-epithelial transition in gastric carcinoma is negatively regulated by its hexapeptide motif. Oncotarget 2015 6(40):42838-53
Xuemin Xue, Naiyan Zeng, Zifen Gao, and Ming-Qing Du Diffuse large B-cell lymphoma: sub-classification by massive parallel quantitative RT-PCR Lab Invest 2015 95: 113-150
Clipson A, Barrans S, Zeng N, Crouch S, Grigoropoulos NF, Liu H, Kocialkowski S, Wang M, Huang Y, Worrillow L, Goodlad J, Buxton J, Neat M, Fields P, Wilkins B, Grant JW, Wright P, Ei-Daly H, Follows GA, Roman E, Watkins AJ, Johnson PW, Jack A, Du MQ The prognosis of MYC translocation positive diffuse large B-cell lymphoma depends on the second hit J Pathol Clin Res. 2015 1(3): 125-133
Christina Soromani, Naiyan Zeng, Klaus Hollemeyer, Elmar Heinzle, Marie-Christine Klein, Thomas Tretter, Matthew N J Seaman and Karin R?misch. N-acetylation and phosphorylation of Sec 3 complex subunits in the ER membrane. BMC Cell Biol. 2012 13:34
Watkins AJ, Hamoudi RA, Zeng N, Yan Q, Huang Y, Liu H, Zhang J, Braggio E, Fonseca R, de Leval L, Isaacson PG, Wotherspoon A, McPhail ED, Dogan A, Du MQ. An integrated genomic and expression analysis of 7q deletion in splenic marginal zone lymphoma. PLoS One. 2012 7(9): e44997
Yan Q, Huang Y, Watkins AJ, Kocialkowski S, Zeng N, Hamoudi RA, Isaacson PG, de Leval L, Wotherspoon A, Du MQ BCR and TLR signaling pathways are recurrently targeted by genetic changes in splenic marginal zone lymphomas Haematologica 2012 97(4):595-8
Yingwen Bi, Naiyan Zeng （共同第一作者）, Estelle Chanudet, Yuanxue Huang, Rifat A. Hamoudi, Hongxiang Liu, Gehong Dong, A James Watkins, Lifen Zou, Rongjia Chen, Xiongzeng Zhu, Ming-Qing Du A20 inactivation in ocular adnexal MALT lymphoma. Haematologica 2012 97(6): 926-930
Gehong Dong, Estelle Chanudet, Naiyan Zeng （共同第一作者）,Alex Appert, Yun-Wen Chen, Wing-Yan Au, Rifat Hamoudi, A. James Watkins, Hongtao Ye, Hongxiang Liu, Zifen Gao, Shih-Sung Chuang, Gopesh Srivastava, and Ming-Qing Du A20, ABIN-1/2 and CARD11 mutations and their prognostic value in gastrointestinal diffuse large B-cell lymphoma Clin Cancer Res. 2011 17(6): 1440-1451
Estelle Chanudet, Yuanxue Huang, Naiyan Zeng, Berthold Streubel, Andreas Chott, Markus Raderer, Ming-Qing Du. TNFAIP3 abnormalities in MALT lymphoma with autoimmunity Brit J Haemotol. 2011 154: 535–539.
Naiyan Zeng （通讯作者）, Lu Liu, Martin G McCabe, David TW Jones, Koichi Ichimura, V Peter Collins Real-time quantitative PCR analysis with FRET probes reveals differential expression of the four ERBB4 juxtamembrane-region variants between medulloblastoma and pilocytic astrocytoma. Neuropath Appl Neuro 2009 35 (4): 353-366.
Ming-Yan Cheung, Nai-Yan Zeng, Suk-Wah Tong, Wing-Yen Francisca Li, Yan Xue, Kai-Jun Zhao, Chunlian Wang, Qi Zhang, Yaping Fu, Zongxiu Sun, Samuel Sai-Ming Sun and Hon-Ming Lam Constitutive expression of a rice GTPase activating protein induces defense responses New Phytol. 2008 179 (2): 530-545
Waiyan Ng, Tatiana Sergeyenko, Naiyan Zeng, Jeremy D Brown, Karin R?misch. Characterization of the proteasome interaction with the Sec61 channel in the endoplasmic reticulum. J Cell Sci. 2007 120 (4): 682-691