导师姓名： 丁峰 专业代码： 100201
性别： 男 专业名称： 内科学
培养单位： 附属第九人民医院 三级学科/
专业领域： 肾病
导师类型： 博士生导师 专业学位导师： 兼
联系方式： 上海市制造局路639号
邮编： 200011 邮箱地址： dingfeng@sjtu.edu.cn

研究方向 (点击浏览详细信息)
血液净化
急性肾损伤
组织工程

社会任职
中华肾脏病学会血液净化专家委员会委员
上海市肾脏病学会委员
上海市肾内科临床质量控制中心专家委员会委员
中国医师协会肾脏医师分会委员
中国研究型医院协会肾脏病专业委员会委员
上海市血液透析临床质量控制中心专家委员会委员
上海市中西医结合学会肾病专委会委员
中国药理学会肾脏药理专业委员会委员
上海医师协会肾脏医师分会副会长
上海市医学会内科学会委员
上海市医学会临床药学分会委员
中国非公立医疗机构协会肾脏病透析专业委员会委员
上海市康复医学会肾脏康复专委会副主任委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 一种用于蛋白结合类毒素清除的脂质体透析液的研制及优化 上海市科委科技创新行动计划 2019-04~2022-03 25万元 课题负责人
** 浆细胞样树突状细胞通过分泌干扰素α加重急性肾损伤的作用及机制研究 国家自然科学基金 2019-01~2022-12 57万元 课题负责人
JYJC201808 基于全血离子钙实时监测的全自动局部枸橼酸抗凝仪 上海交通大学医学院附属第九人民医院 2019-01~2021-12 30万元 课题负责人
2017-1-019 泌尿系结石一体化诊治 上海交通大学医学院附属第九人民医院临床研究型MDT项目 2017-10~2020-09 45万元 课题负责人
** 局部枸橼酸抗凝仪工程化样机的研制 上海市科学技术委员会科技支撑项目 2017-10~2020-09 80万元 课题负责人
JYLJ007 急性肾损伤患者蛋白结合毒素的变化规律及其治疗新策略的研究 上海交通大学医学院附属第九人民医院临床研究助推计划 2016-09~2019-08 40万元 课题负责人
PW2015D-4 连续性肾脏替代疗法局部枸橼酸抗凝新技术的多中心、随机、开放、对照研究 浦东新区卫生和计划生育委员会 2016-01~2018-12 20万元 课题负责人
** 骨髓间充质干细胞生物反应器的构建及对脓毒症大鼠免疫失衡的双向调控作用 国家自然科学基金 2015-01~2018-12 73万元 课题负责人
YG2014ZD06 一种用于血液净化的全自动局部枸橼酸抗凝设备 上海交通大学医工交叉重点项目 2015-01~2017-12 50万元 课题负责人
** 利用药代动力学和清除动力学模型构建 CRRT 局部枸橼酸抗凝方案 国家自然科学基金 2013-01~2016-12 70万元 课题负责人
2011BAI10B08 血液净化质量改进和国产血液净化产品临床应用评价研究 国家科技支撑项目 2012-01~2015-15 15万元 课题参与人
血液净化与灌注成像新技术与新装置的研发 上海市科委重点项目 2011-12~2014-09 40万元 课题负责人
** 转染血栓调节蛋白的内皮细胞生物反应器的构建及在重症脓毒症中的应用 国家自然科学基金 2011-01~2013-12 35万元 课题负责人
利用药代动力学和透析清除动力学模型建立危重病患者局部枸橼酸抗凝方案 上海市科委医学引导类项目 2009-07~2012-09 10万元 课题负责人
** 高级氧化蛋白产物生物学特性的初步研究 国家自然科学基金 2004-01~2006-12 20万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Shi Y, Xiong Y, Lei Y, Li Z, Yan H, Yuan J, Ding F （通讯作者）, Fang W Protective effect of COMP-angiopoietin-1 on peritoneal vascular permeability and peritoneal transport function in uremic peritoneal dialysis rats Am J Transl Res 2019 11(9):5932-5943
Yuxin Qian, Yue Shen, Shuai Deng, Tingyan Liu, Fan Qi, Ziyi Lu, Longqiang Liu, Ning Shao, Jiayang Xie, Feng Ding （通讯作者）, Runhui Liu Dual functional ??peptide polymer?modified resin beads for bacterial killing and endotoxin adsorption BMC Materials 2019 1(5): 1-8
Shi Y, Tian H, Wang Y, Shen Y, Zhu Q, Ding F （通讯作者） Removal of Protein-Bound Uremic Toxins by Liposome-Supported Peritoneal Dialysis Perit Dial Int 2019 39(6):509-518
Shen Y, Wang Y, Shi Y, Bi X, Xu J, Zhu Q, Ding F （通讯作者） Improving the clearance of protein-bound uremic toxins using cationic liposomes as an adsorbent in dialysate Colloids Surf B Biointerfaces 2019 doi: 10.1016/j.colsurfb.2019.110725
Deng B, Lin Y, Chen Y, Ma S, Cai Q, Wang W, Li B, Liu T, Zhou P, He R, Ding F （通讯作者） Plasmacytoid dendritic cells promote acute kidney injury by producing interferon-α Cell Mol Immunol. 2019 doi: 10.1038/s41423-019-0343-9
Wang W, Hao G, Pan Y, Ma S, Yang T, Shi P, Zhu Q, Xie Y, Ma S, Zhang Q, Ruan H, Ding F. （通讯作者） Serum indoxyl sulfate is associated with mortality in hospital-acquired acute kidney injury: a prospective cohort study BMC Nephrol 2019 20(1):57
Xu Y, Wang J, Xu W, Ding F （通讯作者）, Ding W Prohibitin 2-mediated mitophagy attenuates renal tubular epithelial cells injury by regulating mitochondrial dysfunction and NLRP3 inflammasome activation Am J Physiol Renal Physiol 2019 316(2):F396-F407
Yu W, Zhuang F, Ma S, Fan Q, Zhu M, Ding F （通讯作者） Optimized Calcium Supplementation Approach for Regional Citrate Anticoagulation nephron 2019 141(2):119-127
Yang T, Wang W, Tang X, Shi P, Zhang L, Yu W, Xie Y, Guo D, Ding F （通讯作者） Association between mineral and bone disorder in patients with acute kidney injury following cardiac surgery and adverse outcomes BMC Nephrol 2019 20(1):369
Yu W, Zhuang F, Ma S, Zhu M, Ding F （通讯作者） Solutes removal characteristics at various effluent rates during different continuous renal replacement therapy modalities Int J Artif Organs 2019 42(7):354–361
Shen Y, Liu T, Shi Y, Zhuang F, Lu J, Zhu Q, Ding F （通讯作者） Bisphenol A analogs in patients with chronic kidney disease and dialysis therapy Ecotoxicol Environ Saf 2019 doi: 10.1016/j.ecoenv.2019.109684
Shi Y, Wang Y, Ma S, Liu T, Tian H, Zhu Q, Wang W, Li Y, Ding F （通讯作者） Increasing the removal of protein-bound uremic toxins by liposome-supported hemodialysis Artif Organs 2019 43(5):490-503
Zheng Y, Xu Z, Fan Q, Zhu Q, Ma S, Lu J, Zhuang F, Hao G, Lu W, Ding F （通讯作者） Calcium supplementation in CVVH using regional citrate anticoagulation Hemodial Int 2019 23(1):33-41
Shi Y, Zhang Y, Tian H, Wang Y, Shen Y, Zhu Q, Ding F （通讯作者） Improved dialytic removal of protein-bound uremic toxins by intravenous lipid emulsion in chronic kidney disease rats Nephrol Dial Transplant 2019 34(11):1842-52
Yin Zheng, Feng Zhuang, Qiuyu Zhu, Shuai Ma, Yao Xu, Jianxin Lu, Guihua Hao, Yong Gu, Chuanming Hao, Mingli Zhu, Feng Ding （通讯作者） Albumin-corrected total/ionized calcium ratio is not superior to total/ionized calcium ratio as an indicator of citrate accumulation Int J Artif Organs 2017 40(11):602-6
Bo Deng, Yuli Lin, Shuai Ma, Yin Zheng, Xuguang Yang, Bingji Li, Wenyan Yu, Qingqing Xu, Tingyan Liu, Chuanming Hao, Rui He, Feng Ding （通讯作者） The leukotriene B4–leukotriene B4 receptor axis promotes cisplatin-induced acute kidney injury by modulating neutrophil recruitment Kidney International 2017 92:89-100
Shuai Ma, Qingqing Xu, Bo Deng, Yin Zheng, Hongyan Tian, Li Wang, Feng Ding （通讯作者） Granulocyte and monocyte adsorptive apheresis ameliorates sepsis in rats Intensive Care Medicine Experimental 2017 5:18
Wang C, Ma S, Deng B, Lu J, Shen W, Jin B, Shi H, Ding F （通讯作者） The predictive value of the product of contrast medium volume and urinary albumin/creatinine ratio in contrast-induced acute kidney injury Ren Fail 2017 39(1):555-560
Pan Y, Wang W, Wang J, Yang L, Ding F （通讯作者） ISN AKF 0by25 China Consortium. Incidence and Risk Factors of in-hospital mortality from AKI after non-cardiovascular operation: A nationwide Survey in China Sci Rep 2017 7(1):13953
Wenji Wang, Yu Pan, Xiao Tang, Guihua Hao, Yingxin Xie, Shuai Ma, Jianfeng Luo, Daqiao Guo, Feng Ding （通讯作者） Serum prealbumin and its changes over time are associated with mortality in acute kidney injury Scientific Reports 2017 7:41493
Ma S, Lin Y, Deng B, Zheng Y, Hao C, He R, Ding F （通讯作者） Endothelial bioreactor system ameliorates multiple organ dysfunction in septic rats Intensive Care Med Exp 2016 4(1):23
Wei Ding, Honglei Guo, Chengyan Xu, Bin Wang, Minmin Zhang, Feng Ding （通讯作者） Mitochondrial reactive oxygen species-mediated NLRP3 inflammasome activation contributes to aldosterone-induced renal tubular cells injury Oncotarget 2016 7(14):17479-91
Yanjiao Yang, Xiaojiao Zhao, Xiao Tang, Jianxin Lu, Minjie Zhou, Wenji Wang, Lixin Wang, Daqiao Guo, Feng Ding （通讯作者） Comparison of Serum Cystatin C and Creatinine Level Changes for Prognosis of Patients After Peripheral Arterial Angiography Angiology 2015 66(8):766-773
Jing Qian, Junyan Fang, Qiuyu Zhu, Shuai Ma, Wenji Wang, Ying Zheng, Guihua Hao, Bo Deng, Xiaojiao Zhao, Feng Ding （通讯作者） Serum Protein Thiol Levels in Patients with Hospital-Acquired Acute Kidney Injury Kidney Blood Press Res 2015 40:623-629
Li Yang, Guolan Xing, Li Wang, Yonggui Wu, Suhua Li, Gang Xu, Qiang He, Jianghua Chen, Menghua Chen, Xiaohua Liu, Zaizhi Zhu, Lin Yang, Xiyan Lian, Feng Ding Acute kidney injury in China: a cross-sectional survey Lancet 2015 386: 1465-71
Wenji Wang, Yu Pang, Feng Ding （通讯作者） Impact of Prealbumin Levels on Patients With Acute Kidney Injury Angiology 2015 67(3):295-296
Chunrui Wang, Wenji Wang, Shuai Ma, Jianxin Lu, Haiming Shi, Feng Ding. （通讯作者） Reduced Glutathione for Prevention of Renal Outcomes in Patients Undergoing selective coronary angiography or intervention. J Interven Cardiol 2015 28:249–256
Yin Zheng, Zhongye Xu, Qiuyu Zhu, Junfeng Liu, Jing Qian, Huaizhou You, Yong Gu, Chuanming Hao, Zheng Jiao, Feng Ding （通讯作者） Citrate Pharmacokinetics in Critically Ill Patients with Acute Kidney Injury PLoS One 2013 8(6): e65992
Jing Qian, Huaizhou You, Qiuyu Zhu, Shuai Ma, Ying Zhou, Ying Zheng, Junfeng Liu, Dingwei Kuang, Yong Gu, Chuanming Hao, Feng Ding （通讯作者） Nitrotyrosine Level Was Associated with Mortality in Patients with Acute Kidney Injury PLoS One 2013 8(11): e79962
Lingyun Lai, Jing Qian, Yanjiao Yang, Qionghong Xie, Huaizhou You, Ying Zhou, Shuai Ma, Chuanming Hao, Yong Gu, Feng Ding （通讯作者） Is the Serum Vitamin D Level at the Time of Hospital-Acquired Acute Kidney Injury Diagnosis Associated with Prognosis? PloS One 2013 8(5): e64964
Gong Y, Zhang F, Ding F （通讯作者）, Gu Y Elderly patients with acute kidney injury (AKI): Clinical features and risk factors for mortality Arch Gerontol Geriatr 2012 54(2):e47-51
Gong Y, Xu H, Xu Z, Zhang F, Hao C, Gu Y, Lin S, Ding F （通讯作者） Comparison of prognostic value of two kinds of severity scoring systems for hospital mortality prediction on elderly patients with acute kidney injury Aging Clinical and Experimental Research 2012 24(1):74-8
CJ Pino, L Lou, PL Smith, F Ding （通讯作者）, FD Pagani, DA Buffington, HD Humes A selective cytopheretic inhibitory device for use during cardiopulmonary bypass surgery Perfusion 2012 27(4): 311-319
Ding F, Yevzlin AS, Xu ZY, Zhou Y, Xie QH, Liu JF, Zheng Y, DaSilva JR, Humes HD The Effects of Leukocyte Sequestration and Deactivation on Acute Kidney Injury Outcomes in the Intensive Care Unit ASAIO J 2011 57(5): 426-32
Qionghong Xie, Ying Zhou, Zhongye Xu, Yanjiao Yang, Dingwei Kuang, Huaizhou You, Shuai Ma, Chuanming Hao, Yong Gu, Shanyan Lin, Feng Ding （通讯作者） The Ratio of CRP to Prealbumin Levels Predict Mortality in Patients with Hospital-acquired Acute Kidney Injury BMC Nephrology 2011
Ding F, Song JH, Jung JY, Lou L, Wang M, Charles L,Westover A, Smith PL, Buffington DA, Humes HD A Biomimetic Membrane Device that Modulates the Excessive Inflammatory Response to Sepsis PLoS One 2011 6(4): e18584
Qionghong Xie, Junfeng Liu, Yong Gu, Yi Ping, Li You, Jianyong Zhong, Yi Li, Hyo Hasegawa, Weimin Liang, Shanyan Lin, Feng Ding （通讯作者） Endothelial Bioreactor Ameliorates Endotoxin-Induced Sepsis in Swine Blood Purification 2010 29:252-258
Lv Fang, Huaizhou You, Bobin Chen, Zhongye Xu, Liang Gao, Junfeng Liu, Qionghong Xie, Ying Zhou, Yong Gu, Shanyan Lin and Feng Ding Mannitol is an independent risk factor of acute kidney injury after cerebral trauma: a case control study Renal Failure 2010 32: 673-679
Ying Zhou, Huaizhou You, Jing Xin, Yong Gu, Shanyan Lin, Feng Ding （通讯作者） Nephrotic syndrome with minimal change disease following insect bite: case report and a published work review Nephrology 2010
Humes HD, Sobota JT, Ding F （通讯作者）, Song JH A selective cytopheretic inhibitory device to treat the immunological dysregulation of acute and chronic renal failure Blood Purification 2010 29:183-190
You HZ, Yang HC, Zhu QY, Li MX, Xue J, Gu Y, Lin SY, Ding F （通讯作者） Advanced oxidation protein products induce vascular calcification by promoting osteoblastic trans-differentiation of smooth muscle cells via oxidative stress and ERK pathway Renal Failure 2009 31(4):313-9
Kuang D, You H, Ding F, Xue J, Chen J, Ronco C, Gu Y Intima-Media Thickness of the Carotid Artery and Its Correlation Factors in Maintenance Hemodialysis Patients: A Cross-Sectional Study Blood Purif. 2009 28(3):181-186
Kuang D, You H, Ding F, Xue J, Chen J, Ronco C, Gu Y Intima-Media Thickness of the Carotid Artery and Its Correlation Factors in Maintenance Hemodialysis Patients: A Cross-Sectional Study Blood Purif. 2009 28(3):181-186
Ding F, Humes HD （通讯作者） The bioartificial kidney and bioengineered membranes in acute kidney injury Nephron Exp Nephrol 2008 109(4):e118-22
Humes HD, Ding F, Song JH Dialysis dosing in critically ill patients with acute kidney injury Am J Kidney Dis 2008 52(4):649-52
Y Gu, F Ding, N Chen Comparisons between oral pulse alfacalcidol therapy and daily therapy in maintenance hemodialysis patients with secondary hyperparathyroidism: a randomized, controlled, and multicenter study Renal failure 2005 27(2):205-211
XF Shi, F Ding, QY Zhu Use of ascorbate-rich dialysate to attentuate oxidative stress in maintenance hemodialysis patients Renal failure 2005 27(2):212-219
Su X, Bai C, Hong Q, Zhu D, He L, Wu J, Ding F, Fang X, Matthay MA Effect of continuous hemofiltration on hemodynamics, lung inflammation and pulmonary edema in a canine model of acute lung injury Intensive Care Med 2003 29(11):2034-42
F Ding, P Ahrenholz, RE Winkler Online hemodiafiltration versus acetate-free biofiltration: a prospective crossover study Artificial Organs 2002 26(2): 169-180