导师姓名： 包玉倩 专业代码： 100201
性别： 女 专业名称： 内科学
培养单位： 附属第六人民医院 三级学科/
专业领域： 内分泌与代谢病
导师类型： 博士生导师 专业学位导师： 兼
联系方式：
邮编： 200233 邮箱地址： byq522@163.com

研究方向 (点击浏览详细信息)
肥胖与糖尿病的发病机制及干预研究

社会任职
上海市医学会糖尿病专科分会前任主任委员
中华医学会糖尿病学分会常务委员
中华预防医学会糖尿病预防与控制专业委员会副主任委员
中华医学会糖尿病学分会血糖监测学组组长
上海市医学会糖尿病专科分会代谢综合征学组组长

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 颈围对动脉硬化及主要不良心血管事件的预测作用——社区人群队列5年随访研究 上海市医学引导类(中、西医)科技支撑项目 2019-03~2022-03 20万元 课题负责人
SHDC** 唾液1,5-脱水葡萄糖醇正常值的建立及临床应用 市级医院新兴前沿技术联合攻关项目 2016-09~2019-09 180万元 课题负责人
2016YFA** 代谢感应蛋白质机器在肥胖等重大疾病中的生理病理作用 国家重点研发计划 2016-07~2021-06 625万元 课题负责人
** 骨钙素通过GPRC6A调控肝脏脂质代谢的分子机制 国家自然科学基金面上项目 2016-01~2019-12 76.8万元 课题负责人
15ZH4006 基于糖尿病病因及病理生理功能的精准医学个体化诊断及 上海交通大学医学院转化医学创新基金（第二期）——精准医学研究项目 2015-09~2017-08 100万元 课题负责人
2013ZYJB1001 同一社区人群多种代谢性疾病的前瞻性队列研究 上海市卫生系统重要疾病联合攻关项目 2014-01~2016-12 300万元 课题负责人
13XD** 上海市优秀学科带头人 上海市科委 2013-07~2015-06 40万元 课题负责人
** 骨钙素在动脉粥样硬化发病过程中的调控机制 国家自然基金面上项目 2012-01~2015-12 58万元 课题负责人
047 上海市领军人才 上海市人力资源和社会保障局 2011-12~2016-12 80万元 课题负责人
2011 上海交通大学医学院优秀学科带头人 上海交通大学医学院 2011-01~2016-12 150万元 课题负责人
2009BA180B01 代谢综合征的诊断标准和诊断规范 科技部 2010-04~2012-12 990万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Xu Y, Ma X, Shen Y, Gu C, Tang J, Bao Y （通讯作者） Role of hyperglycaemia in the relationship between serum osteocalcin levels and relative skeletal muscle index Clin Nutr 2019 38(6):2704-2711
Zhang XL, Shen Y, Ma XJ, Lu ZG, Xu YT, Xiong Q, Bao YQ （通讯作者） Low serum osteocalcin levels are correlated with left ventricular systolic dysfunction and cardiac death in Chinese men Acta Pharmacol Sin 2019 40(4): 486-491
Nie X, Xu Y, Ma X, Shen Y, Wang Y, Bao Y （通讯作者） Trunk fat and leg fat in relation to free triiodothyronine in euthyroid postmenopausal women Endocr Connect 2019 8(10):1425–1432
Xu Y, Ma X, Pan X, He X, Wang Y, Bao Y （通讯作者） Serum adipocyte fatty acid-binding protein levels: An indicator of non-alcoholic fatty liver disease in Chinese individuals Liver Int 2019 39(3):568-574
Xu Y, Ma X, Shen Y, Wang Y, Zhou J, Bao Y （通讯作者） Increasing waist circumference is associated with decreased levels of glycated albumin Clin Chim Acta 2019 495: 118-122
Xu Y, Ma X, Shen Y, Xiong Q, Zhang X, Bao Y （通讯作者） Serum osteocalcin level as an indicator of low-grade albuminuria in Chinese men free of kidney disease Curr Med Res Opin 2019 35(4):667-673
Bao Y, Chen L, Chen L, Dou J, Gao Z, Gao L, Guo L, Guo X, Ji L, Ji Q, Jia W,Kuang H, Li Q, Li Q, Li X, Li Y, Li L, Liu J, Ma J, Ran X, Shi L, Song G, Wang Y,Weng J, Xiao X, Xie Y, Xi G, Yang L, Zhao Z, Zhou J, Zhou Z, Zhu D, Zou D Chinese Diabetes Society. Chinese clinical guidelines for continuous glucose monitoring (2018 edition). Diabetes Metab Res Rev. 2019 35(6):e3152
Yu H, Li Q, Zhang M, Liu F, Pan J, Tu Y, Lu J, Zhang P, Han J, Jia W, Bao Y （通讯作者） Decreased Leptin Is Associated with Alterations in Thyroid-Stimulating Hormone Levels after Roux-en-Y Gastric Bypass Surgery in Obese Euthyroid Patients with Type 2 Diabetes Obes Facts 2019 12(3):272-280
Xu Y, Shen Y, Ma X, Gu C, Wang Y, Bao Y （通讯作者） First-degree family history of diabetes and its relationship with serum osteocalcin levels independent of liver fat content in a non-diabetic Chinese cohort BMC Public Health 2019 19(1):1628
Shen Y, Zhang X, Xu Y, Xiong Q, Lu Z, Ma X, Bao Y （通讯作者）, Jia W Serum FGF21 Is Associated with Future Cardiovascular Events in Patients with Coronary Artery Disease. Cardiology 2018 139(4): 212-218
Xu Y, Ma X, Xiong Q, Zhang X, Shen Y, Bao Y. （通讯作者） Osteocalcin value to identify subclinical atherosclerosis over atherosclerotic cardiovascular disease (ASCVD) risk score in middle-aged and elderly Chinese asymptomatic men Clin Chem Lab Med 2018 56(11): 1962-1969
Bao Y Paired editorial: biphasic changes in angiopoietin-like 8 level after laparoscopic sleeve gastrectomy and type 2 diabetes remission during a 1-year follow-up Surg Obes Relat Dis 2018 14(9): 1295-1296
Hu X, Ma X, Luo Y, Xu Y, Xiong Q, Pan X, Xiao Y, Bao Y （通讯作者）, Jia W Associations of serum fibroblast growth factor 23 levels with obesity and visceral fat accumulation Clin Nutr 2018 37(1): 223-228
Hu X, Xiong Q, Xu Y, Zhang X, Xiao Y, Ma X, Bao Y （通讯作者） Contribution of maternal diabetes to visceral fat accumulation in offspring Obes Res Clin Pract 2018 12(5): 426-431
Zhang X, Shen Y, Xu Y, Xiong Q, Lu Z, Ma X, Bao Y （通讯作者）, Jia W. Association of serum osteocalcin levels with major adverse cardiovascular events: A 4.4-year retrospective cohort study. Clin Exp Pharmacol Physiol 2018 45(1): 3-9
Zhou J, Zhang S, Li L, Wang Y, Lu W, Sheng C, Li Y, Bao Y# （通讯作者）, Jia W. Performance of a new real-time continuous glucose monitoring system: A multicenter pilot study J Diabetes Investig 2018 9(2): 286-293
Hu X, Xiong Q, Xu Y, Zhang X, Pan X, Ma X, Bao Y （通讯作者）, Jia W Association of serum fibroblast growth factor 19 levels with visceral fat accumulation is independent of glucose tolerance status Nutr Metab Cardiovasc Dis 2018 28(2): 119-125
Xu Y, Ma X, Pan X, He X, Xiao Y, Bao Y （通讯作者） Correlations between serum concentration of three bone-derived factors and obesity and visceral fat accumulation in a cohort of middle aged men and women Cardiovasc Diabetol 2018 17(1):143
Xu Y, Ma X, Xiong Q, Hu X, Zhang X, Yuan Y, Bao Y. （通讯作者） Association between serum osteocalcin level and blood pressure in a Chinese population Blood Press 2018 27(2): 106-111
Luo Y, Ma X, Shen Y, Xu Y, Xiong Q, Zhang X, Xiao Y, Bao Y （通讯作者）, Jia W Neck circumference as an effective measure for identifying cardio-metabolic syndrome: a comparison with waist circumference. Endocrine 2017 55(3):822-830
Xiong Q, Hu X, Xu Y, Zhang X, Pan X, Xiao Y, Ma X, Bao Y （通讯作者）, Jia W. Association of visceral fat area with the presence of depressive symptoms in Chinese postmenopausal women with normal glucose tolerance Menopause 2017 24(11): 1289-1294
Xiong Q, Hu X, Xu Y, Zhang X, Pan X, Xiao Y, Ma X, Bao Y （通讯作者）, Jia W. Association of visceral fat area with the presence of depressive symptoms in Chinese postmenopausal women with normal glucose tolerance Menopause 2017 Jun 19
Hu X, Ma X, Luo Y, Xu Y, Xiong Q, Pan X, Bao Y （通讯作者）, Jia W Contribution of serum adipocyte fatty acid-binding protein levels to the presence of microalbuminuria in a Chinese hyperglycemic population J Diabetes Investig 2017 8(4):582-589.
Shen Y, Zhang X, Pan X, Xu Y, Xiong Q, Lu Z, Ma X, Bao Y （通讯作者）, Jia W. Contribution of serum FGF21 level to the identification of left ventricular systolic dysfunction and cardiac death Cardiovasc Diabetol 2017 16(1): 106
Hu X, Ma X, Luo Y, Xu Y, Xiong Q, Pan X, Bao Y （通讯作者）, Jia W Contribution of fibroblast growth factor 23 to Framingham risk score for identifying subclinical atherosclerosis in Chinese men Nutr Metab Cardiovasc Dis 2017 27(2):147-153
Du J, Zhang M, Lu J, Zhang X, Xiong Q, Xu Y, Bao Y （通讯作者）, Jia W Osteocalcin improves nonalcoholic fatty liver disease in mice through activation of Nrf2 and inhibition of JNK Endocrine 2016 53(3):701-709.
Hu X, Pan X, Ma X, Luo Y, Xu Y, Xiong Q, Xiao Y, Bao Y （通讯作者）, Jia W. Contribution of a first-degree family history of diabetes to increased serum adipocyte fatty acid binding protein levels independent of body fat content and distribution Int J Obes (Lond) 2016 40(11):1649-1654.
Hu X, Ma X, Luo Y, Xu Y, Xiong Q, Pan X, Xiao Y, Bao Y （通讯作者）, Jia W. Associations of serum fibroblast growth factor 23 levels with obesity and visceral fat accumulation Clin Nutr 2016 pii: S0261-5614(16)31351-31356
Luo Y, Ma X, Hao Y, Xiong Q, Xu Y, Pan X, Bao Y （通讯作者）, Jia W. Relationship between serum osteocalcin level and carotid intima-media thickness in a metabolically healthy Chinese population. Cardiovasc Diabetol 2015 14:82
Hu X, Ma X, Pan X, Hao Y, Luo Y, Lu Z, Bao Y （通讯作者）, Jia W Fibroblast growth factor 23 is associated with the presence of coronary artery disease and the number of stenotic vessels Clin Exp Pharmacol Physiol 2015 42(11):1152-1157
Luo Y, Ma X, Hao Y, Xu Y, Xiong Q, Tang J, Pan X, Xiao Y, Bao Y （通讯作者）, Jia W. Association between serum osteocalcin level and visceral obesity in Chinese postmenopausal women Clin Endocrinol (Oxf) 2015 83(3):429-34
Hao Y, Ma X, Luo Y, Hu X, Pan X, Xiao Y, Bao Y （通讯作者）, Jia W. Associations of serum adipocyte fatty acid binding protein with body composition and fat distribution in nondiabetic Chinese women. J Clin Endocrinol Metab 2015 100(5):2055-62
Luo YQ, Ma XJ, Hao YP, Pan XP, Xu YT, Xiong Q, Bao YQ* （通讯作者）, Jia WP. Inverse relationship between serum osteocalcin levels and nonalcoholic fatty liver disease in postmenopausal Chinese women with normal blood glucose. Acta Pharmacol Sin 2015 36(12):1497-1502
Lu Z, Pan X, Hu Y, Hao Y, Luo Y, Hu X, Ma X, Bao Y （通讯作者）, Jia W. Serum Vitamin D Levels Are Inversely Related with Nonalcoholic Fatty Liver Disease Independent of Visceral Obesity in Chinese Postmenopausal Women Clin Exp Pharmacol Physiol 2015 42(2):139-145
Zhang L, Shen Y, Zhou J, Pan JM, Yu HY, Chen HB, Li Q, Li M, Bao YQ （通讯作者）, Jia WP Relationship between Waist Circumference and Elevation of Carotid Intima-media Thickness in Newly-diagnosed Diabetic Patients Biomed Environ Sci 2014 27(5):335-342
Dou J, Li H, Ma X, Zhang M, Fang Q, Nie M, Bao Y （通讯作者）, Jia W Osteocalcin attenuates high fat diet-induced impairment of endothelium-dependent relaxation through Akt/eNOS-dependent pathway Cardiovasc Diabetol 2014 13(1):74
Hao Y, Ma X, Luo Y, Ni J, Dou J, Zhu J, Bao Y* （通讯作者）, Jia W Additional role of serum 25-hydroxyvitamin D(3) levels in atherosclerosis in Chinese middle-aged and elderly men Clin Exp Pharmacol Physiol 2014 41(3):174-179
Hao Y, Ma X, Luo Y, Shen Y, Dou J, Pan X, Bao Y （通讯作者）, Jia W Serum adipocyte fatty acid binding protein levels are positively associated with subclinical atherosclerosis in Chinese pre- and postmenopausal women with normal glucose tolerance J Clin Endocrinol Metab 2014 2014 Aug 15:jc**
Xie G, Ma X, Zhao A, Wang C, Zhang Y, Nieman D, Nicholson JK, Jia W, Bao Y （通讯作者）, Jia W The Metabolite Profiles of the Obese Population Are Gender-Dependent. J Proteome Res 2014 13(9):4062-4073
Hao YP, Ma XJ, Luo YQ, Ni J, Dou JX, Hu YQ, Zhu JA, Bao YQ （通讯作者）, Jia WP Serum vitamin D is associated with non-alcoholic fatty liver disease in Chinese males with normal weight and liver enzymes Acta Pharmacol Sin 2014 35(9):1150-1156
Shen Y, Zhang L, Zong WH, Wang Z, Zhang Y, Yang MJ, Ma XJ, Zhu JA, Bao YQ （通讯作者）, Jia WP Correlation between waist circumference and carotid intima-media thickness in women from Shanghai, China Biomed Environ Sci 2013 26(7):531-538
Shen Y, Ma X, Zhou J, Pan X, Hao Y, Zhou M, Lu Z, Gao M, Bao Y （通讯作者）, Jia W Additive relationship between serum fibroblast growth factor 21 level and coronary artery disease Cardiovasc Diabetol 2013 12(1):124
Dou J, Ma X, Fang Q, Hao Y, Yang R, Wang F, Zhu J, Bao Y （通讯作者）, Jia W Relationship between Serum Osteocalcin Levels and NAFLD Clin Exp Pharmacol Physiol 2013 40(4):282-288
Yang R, Ma X, Pan X, Wang F, Luo Y, Gu C, Bao Y （通讯作者）, Jia W Serum osteocalcin levels in relation to metabolic syndrome in Chinese postmenopausal women Menopause 2013 20(5):548-553
Yang R, Ma X, Dou J, Wang F, Luo Y, Li D, Zhu J, Bao Y （通讯作者）, Jia W Relationship between serum osteocalcin levels and carotid intima-media thickness in Chinese postmenopausal women Menopause 2013 20(11):1194-1199
Ni J, Ma X, Zhou M, Pan X, Tang J, Hao Y, Lu Z, Gao M, Bao Y （通讯作者）, Jia W Serum lipocalin-2 levels positively correlate with coronary artery disease and metabolic syndrome Cardiovasc Diabetol 2013 12(1):176
Wang F, Ma X, Zhou M, Pan X, Ni J, Gao M, Lu Z, Hang J, Bao Y （通讯作者）, Jia W Serum pigment epithelium-derived factor levels are independently correlated with the presence of coronary artery disease Cardiovasc Diabetol 2013 12(1):56-56
Bao Y, Ma X, Yang R, Wang F, Hao Y, Dou J, He H, Jia W Inverse Relationship between Serum Osteocalcin Levels and Visceral Fat Area in Chinese Men J Clin Endocrinol Metab 2013 98(1):345-351
Y Wang, X Ma, M Zhou, W Zong, L Zhang, Y Hao, J Zhu, Y Xiao, D Li, Y Bao （通讯作者）, W Jia Contribution of visceral fat accumulation to carotid intima–media thickness in a Chinese population Int J Obes 2012 36(9):1203-1208
Bao YQ, Zhou M, Zhou J, Lu W, Gao YC, Pan XP, Tang JL, Lu HJ, Jia WP Inverse Relationship between Serum Glipizide controlled-release tablets, with or without acarbose, improve Relationship between serum osteocalcin and glycaemic variability in Type 2 diabetes Clin Exp Pharmacol Physiol 2011 38(1):50-54
Bao Y, Zhou M, Lu Z, Li H, Wang Y, Sun L, Gao M, Wei M, Jia W Serumlevels of osteocalcin are inversely associatedwith the metabolic syndrome and the severity of coronary artery disease in Chinese men Clin Endocrinol (Oxf) 2011 75(2):196-201
Bao YQ, Zhou J, Zhou M, Cheng YJ, Lu W, Pan XP, Tang JL, Lu HJ, Jia WP Inverse Relationship between Serum Glipizide controlled-release tablets, with or without acarbose, improve glycaemic variability in newly diagnosed Type 2 diabetes Clin Exp Pharmacol Physiol 2010 37(5-6):564-568
Bao Y, Ma X, Li H, Zhou M, Hu C, Wu H, Tang J, Hou X, Xiang K, Jia W Glycated haemoglobin A1c for diagnosing diabetes in Chinese population: cross sectional epidemiological survey BMJ 2010 340:c2249
Zhou M,Ma X,Li H,Pan X,Tang J,Gao Y,Hou X （通讯作者）,Bao Y,Jia W Serum osteocalcin concentrations in relation to glucose and lipid metabolism in Chinese individuals European Eur J Endocrinol 2009 161: 723–729
Bao Y, Zhao T, Wang X, Qiu Y, Su M, Jia W, Jia W Metabonomic Variations in the Drug-Treated Type 2 Diabetes Mellitus Patients and Healthy Volunteers J Proteome Res 2009 8:1623–1630
Bao Yuqian, Lu Junxi, Wang Chen, Yang Ming, Li Huating, Zhang Xiaoyan, Zhu Jiehua, Lu Huijuan, Jia Weiping, Xiang Kunsan Optimal waist circumference cutoffs for abdominal obesity in Chinese Atherosclerosis 2008 201:378-384