导师姓名： 贾伟 专业代码： 100201
性别： 男 专业名称： 内科学
培养单位： 附属第六人民医院 三级学科/
专业领域： 内分泌与代谢病
导师类型： 博士生导师 专业学位导师：
联系方式： wjia4226@hotmail.com
邮编： 200233 邮箱地址： wjia4226@hotmail.com

研究方向 (点击浏览详细信息)
代谢组学技术在转化医学中的应用

社会任职
上海市第六人民医院转化医学中心主任

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 肠道BSH细菌-FXR-ASBT介导的牛磺胆酸对肝性脑病的影响 国家自然科学基金面上项目 2020-01~2023-12 55万元 课题负责人
2017YFC** 临床样本代谢组的超灵敏高覆盖定量分析技术研究 科技部 2017-12~2019-12 194万元 课题参与人
SH03036 基于代谢组学的转化医学研究 上海市**** 2014-09~2017-08 600万元 课题负责人
2014DFA31870 中国人2型糖尿病的分子分型及在疾病早期预警中的作用 国家科技部国际合作项目 2014-04~2016-12 177万元 课题负责人
2007CB914700 代谢性疾病的蛋白质功能与代谢组学研究 国家科技部重大科学研究计划项目（973计划） 2007-01~2011-12 1600万元 课题负责人
** 基于代谢组学的肾阳虚证本质的研究 国家自然科学基金面上项目 2006-01~2008-12 25万元 课题参与人
2006DFA02700 扶正化瘀片(药物代谢和毒理)的国际化示范研究 国家科技部国际合作项目 2006-01~2008-12 80万元 课题负责人
05DJ14009 上海地区典型恶性肿瘤的代谢组学研究 上海市科委重大基础研究项目 2005-10~2008-09 480万元 课题负责人
2005年 代谢组学研究复方中药治疗糖尿病肾病的机制 上海市教委曙光（人才）计划项目 2005-01~2006-12 12万元 课题负责人
04DZ19843 中药药对的药效物质基础和作用机制研究 上海市科委中药现代化专项课题 2004-10~2006-09 179万元 课题负责人
2004年 多元膦酸络合物治疗转移性骨肿瘤的研究 教育部“新世纪优秀人才计划”项目 2004-01~2007-12 50万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Xie Guoxiang, Wang Xiaoning, Wei Runmin, Wang Jingye, Zhao Aihua, Chen Tianlu, Wang Yixing, Zhang Hua, Xiao Zhun, Liu Xinzhu, Deng Youping, Wong Linda, Rajani Cynthia, Kwee Sandi, Bian Hua, Gao Xin, Liu Ping, Jia Wei （通讯作者） Serum Metabolite Profiles are Associated with the Presence of Advanced Liver Fibrosis in Chinese Patients with Chronic Hepatitis B Viral Infection BMC Medicine 2020 18(1): 144
Wei Meilin, Huang Fengjie, Zhao Ling, Zhang Yunjing, Yang Wei, Wang Shouli, Li Mengci, Han Xiaolong, Ge Kun, Qu Chun, Rajani Cynthia, Xie Guoxiang, Zheng Xiaojiao, Zhao Aihua, Bian Zhaoxiang, Jia Wei （通讯作者） A Dysregulated Bile Acid-Gut Microbiota Axis Contributes to Obesity Susceptibility EBioMedicine 2020 55: 102766
Zhang Yunjing, Jiang Runqiu, Zheng Xiaojiao, Lei Sha, Huang Fengjie, Xie Guoxiang, Kwee Sandi, Yu Herbert, Farrar Christine, Sun Beicheng, Zhao Aihua, Jia Wei （通讯作者） Ursodeoxycholic Acid Accelerates Bile Acid Enterohepatic Circulation British journal of pharmacology 2019 76(16)：2848-2863
Jia Wei, Rajani Cynthia, Kaddurah-Daouk Rima, Li Houkai Expert insights: The potential role of the gut microbiome-bile acid-brain axis in the development and progression of Alzheimer's disease and hepatic encephalopathy Medicinal Research Reviews 2019 Dec 5
Huang Fengjie, Wang Shouli, Zhao Aihua, Zheng Xiaojiao, Zhang Yunjing, Lei Sha, Ge Kun, Qu Chun, Zhao Qing, Yan Chao, Jia Wei （通讯作者） Pu-erh Tea Regulates Fatty Acid Metabolism in Mice Under High-Fat Diet Frontiers in pharmacology 2019 10:63
Huang Fengjie, Zheng Xiaojiao, Ma Xiaohui, Jiang Runqiu, Zhou Wangyi, Zhou Shuiping, Zhang Yunjing, Lei Sha, Wang Shouli, Kuang Junliang, Han Xiaolong, Wei Meilin, You Yijun, Li Mengci, Li Yitao, Liang Dandan, Liu Jiajian, Chen Tianlu, Yan Chao, Wei Runmin, Rajani Cynthia, Shen Chengxing, Xie Guoxiang, Bian Zhaoxiang, Li Houkai, Zhao Aihua, Jia Wei （通讯作者） Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism Nature Communications 2019 10(1): 4971
Zhang Yunjing, Zheng Xiaojiao, Huang Fengjie,Zhao Aihua, Ge Kun, Zhao Qing, Jia Wei （通讯作者） Ursodeoxycholic Acid Alters Bile Acid and Fatty Acid Profiles in a Mouse Model of Diet-Induced Obesity Frontiers in Pharmacology 2019 10: 842
Tianlu Chen, Yijun You, Guoxiang Xie, Xiaojiao Zheng, Aihua Zhao, Jiajian Liu, Qing Zhao, Shouli Wang, Fengjie Huang, Cynthia Rajani, Congcong Wang, Shaoqiu Chen, Yan Ni, Herbert Yu, Youping Deng, Xiaoyan Wang, Wei Jia* （通讯作者） Strategy for an Association Study of the Intestinal Microbiome and Brain Metabolome Across the Lifespan of Rats Aanlytical Chemistry 2018 94(4): 2475-2483
Li, Mengci, Shouli Wang, Guoxiang Xie, Xiaohui Ma, Tianlu Chen and Wei Jia （通讯作者） PolyPK: an R Package for Pharmacokinetic Analysis of Multi-Component Drugs Using a Metabolomics Approach Bioinformatics 2018 34(10):1792-1794
Xie Guoxiang, Wang Shouli,Zhang Hua,Zhao Aihua,Liu Jiajian, Ma Yueming,Lan Ke,Ni Yan,Liu Changxiao,Liu Ping,Chen Tianlu, Jia Wei. （通讯作者） Poly-Pharmacokinetic Study of a Multicomponent Herbal Medicine in Healthy Chinese Volunteers Clinical pharmacology and therapeutics 2018 103(4):692-702
Rajani, C. （通讯作者）, Jia, W Disruptions in gut microbial-host co-metabolism and the development of metabolic disorders Clinical Science 2018 132(7), 791-811
Zheng Xiaojiao,Wang Shouli,Jia Wei （通讯作者） Calorie Restriction and its Impact on Gut Microbial Composition and Global Metabolism Frontiers of Medicine 2018 12(6):634-44
Jia Wei （通讯作者）, Xie Guoxiang Probiotics, Bile Acids and Gastrointestinal Carcinogenesis Nature Reviews. Gastroenterology & Hepatology 2018 15(4):205
Guoxiang Xie, Xiaoning Wang, Runqiu Jiang, Aihua Zhao, Jingyu Yan , Xiaojiao Zheng , Fengjie Huang , Xinzhu Liu, Jun Panee, Cynthia Rajani, Chun Yao, Herbert Yu, Weiping Jia, Beicheng Sun, Ping Liu, Wei Jia* （通讯作者） Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure EBioMedicine 2018 37:294-306
（5）Zheng, X.J., Zhou, K.J., Zhang, Y.J., Han, X.L., Zhao, A.H., Liu, J.J., Qu, C., Ge （通讯作者）, K., Huang, F.J., Hernandez, B., Yu, H., Panee, J., Chen, T.L., Jia, W.P., Jia, W.* Food withdrawal alters the gut microbiota and metabolome in mice The FASEB Journal 2018 32(9):4878-4888
Jia （通讯作者）, W.*, Xie, G.X. Jia, W.P. Bile acid-microbiota crosstalk in gastrointestinal carcinogenesis Nature Reviews Gastroenterology and Hepatology 2018 15(2):111-128
Xie Guoxiang, Wang Xiaoning, Zhao Aihua, Yan Jingyu, Chen Wenlian, Jiang Runqiu,Ji Junfang, Huang Fengjie, Zhang Yunjing, Lei Sha, Ge Kun , Zheng Xiaojiao,Rajani Cynthia,Alegado Rosanna A., Liu Jiajian , Liu Ping Liu, Nicholson Jeremy, Jia Wei* （通讯作者） Sex-dependent effects on gut microbiota regulate hepatic carcinogenic outcomes Scentific Reports 2017 7:45232
Zhao Linjing, Ni Yan, Su Mingming, Li Hongsen, Dong Fangcong, Chen Wenlian, Wei Runmin, Zhang Lulu, Guiraud Seu Ping, Martin Francois-Pierre, Rajani Cynthia, Xie Guoxiang, Jia Wei* （通讯作者） High throughput and quantitative measurement of microbial metabolome by gas Analytical Chemistry 2017 89(10):5565-5577
Zhao Linjing, Ni Yan, Yu Haoyong, Zhang Pin, Zhao Aihua, Bao Yuqian, Liu Jiajian, Chen Tianlu, Xie Guoxiang, Panee Jun, Chen Wenlian,Rajani Cynthia, Wei Runmin, Su Mingming, Jia Weiping*, and Jia Wei* （通讯作者） Serum Stearic Acid/ Palmitic Acid Ratio as a Potential Predictor of Diabetes Remission after Roux-En-Y Gastric Bypass in Obesity FASEB Journal 2017 31(4):1449-1460
Xie Guoxiang, Wang Shouli, Zhang Hua, Zhao Aihua,Liu Jiajian, Ma Yueming,Lan Ke, Ni Yan, Liu Changxiao, Liu Ping, Chen Tianlu, Jia Wei* （通讯作者） Poly-Pharmacokinetic Study of a Multicomponent Herbal Medicine in Healthy Chinese Volunteers Clinical Pharmcology and Therapeutics 2017 doi: 10.1002/cpt.784
Lei Sha, Huang Fengjie, Zhao Aihua, Chen Tianlu, Chen Wenlian, Xie Guoxiang, Zheng Xiaojiao,Zhang Yunjing, Yu Haoyong, Zhang Pin, Rajani Cynthia, bao Yuqian, Jia Weiping,and Jia Wei* The ratio of dihomo-γ-linolenic acid to deoxycholic acid species is a potential biomarker for the metabolic abnormalities in obesity FASEB Journal 2017 doi: 10.1096/fj.R
Zhao Linjing, Ni Yan, Ma Xiaojing, Zhao Aihua, Bao Yuqian, Liu Jiajian, Chen Tianlu, Xie Guoxiang, Panee Jun, Su Mingming, Yu Herbert, Wang Congrong, Hu Cheng, Jia Weiping,Jia Wei （通讯作者） A Panel of Free Fatty Acid Ratios to Predict the Development of Metabolic Abnormalities in Healthy Obese Individuals Scientific Reports 2016 6: 28418
Zheng Xiaojiao, Chen Tianlu, Zhao Aihua, Wang Xiaoyan, Xie Guoxiang, Huang Fengjie, Liu Jiajian, Zhao Qing, Wang Shouli, Wang Chongchong, Zhou Mingmei, Panee Jun, He Zhigang,Jia Wei （通讯作者） The Brain Metabolome of Male Rats across the Lifespan Scientific Reports 2016 6: 24125
Xie Guoxiang, Wang Xiaoning, Liu Ping, Wei Runmin, Chen Wenlian, Rajani Cynthia, Hernandez Brenda Y, Alegado Rosanna, Dong Bing, Li Defa,Jia Wei （通讯作者） Distinctly Altered Gut Microbiota in the Progression of Liver Disease Oncotarget 2016 7(15):19355-19366
Chen WenLian, Wang Yueying, Zhao Aihua, Xia Li, Xie Guoxiang, Su Mingming, Zhao Linjing,Liu Jiajian, Qu Chun, Wei Runmin,Rajani Cynthia, Ni Yan,Cheng Zhen, Chen Zhu, Chen Saijuan,and Wei Jia （通讯作者） Enhanced Fructose Utilization Mediated by SLC2A5 Is a Unique Metabolic Feature of Acute Myeloid Leukemia with Therapeutic Potential Cancer Cell 2016 30(5):779-791
Xie Guoxiang, Wang Xiaoning, Huang Fengjie, Zhao Aihua, Chen Wenlian, Yan Jingyu, Zhang Yunjing, Lei Sha, Ge Kun, Zheng Xiaojiao, Liu Jiajian, Su Mingming, Liu Ping,Jia Wei （通讯作者） Dysregulated Hepatic Bile Acids Collaboratively Promote Liver Carcinogenesis International Journal of Cancer 2016 139(8):1764-75
Chen Tianlu, Ni Yan, Ma Xiaojing, Bao Yuqian, Liu Jiajian, Huang Fengjie, Hu Cheng, Xie Guoxiang, Zhao Aihua, Jia Weiping,Jia Wei （通讯作者） Branched-Chain and Aromatic Amino Acid Profiles and Diabetes Risk in Chinese Populations Scientific Reports 2016 6:20594
Xie Guoxiang, Wang Yixing, wang Xiaoning, Zhao Aihua, Chen Tianlu, Ni Yan, Wong Linda, Zhang Hua, Zhang Jue, Liu Chang, Liu Ping*, Jia Wei* （通讯作者） Profiling of serum bile acids in a healthy Chinese population using UPLC-MS/MS Journal of Proteome Research 2015 14(2):850-859
Wu Tao, Xie Guoxiang, Ni Yan, Liu Tao , Yang Ming, Wei Huafeng, Jia Wei* （通讯作者）, Ji Guang* Serum Metabolite Signatures of Type 2 Diabetes Mellitus Complications Journal of Proteome Research 2015 14(1):447-456
Cai Lei, Chen Tianlu,Yang Jinglei,Zhou Kejun,Yan Xiaomei,Chen Wenzhong,Sun Liya,Li Linlin,Qin Shengying,Wang Peng,Yang Ping,Cui Donghong,Burmeister Margit,He Lin*,Jia Wei* （通讯作者）,Wan Chunling* erum Trace Element Differences between Schizophrenia Patients and Controls in the Han Chinese Population Scientific Reports 2015 5:15013
Xie Guoxiang, Zhou Bingsen,Zhao Aihua,Qiu Yunping,Zhao Xueqing,Garmire Lana,Shvetsov Yurii. B,Yu Herbert,Yen Yun*,Jia Wei* （通讯作者） Lowered Circulating Aspartate is a Metabolic Feature of Human Breast Cancer Oncotarget 2015 6(32):33369-33381
Jia Wei* （通讯作者）,Lu Aiping,Chan Kelvin,Gustafsson Mats G Liu Ping Translational Research in Complementary and Alternative Medicine 2014 Evidence-Based Complementary and Alternative Medicine 2015 427508
Jia Wei* （通讯作者）,Pan Taiping Fan, Wang Xiaoning, Xie Guoxiang The polypharmacokinetics of herbal medicines Science, Special issue: The Art and Science of Traditional Medicine 2015 S76-77
Xie Guoxiang,Lu Lingeng,Qiu Yunping,Ni Quanxing,Zhang Wei,Gao Yu-Tang,Risch Harvey A,Yu Herbert,Jia Wei* （通讯作者） Plasma Metabolite Biomarkers for the Detection of Pancreatic Cancer Journal of Proteome Research 2015 14(2):1195-1202
Ni Yan,Zhao Linjing,Yu Haoyong,Ma Xiaojing,Bao Yuqian,Rajani Cynthia,Loo Lenora W.M.,Shvetsov Yurii B.,Yu Herbert,Chen Tianlu,Zhang Yinan,Wang Congrong,Hu Cheng,Su Mingming,Xie Guoxiang,Zhao Aihua,Jia Wei* （通讯作者）,Jia Weiping* Circulating Unsaturated Fatty Acids Delineate the Metabolic Status of Obese Individuals EBioMedicine 2015 2(10):1513-1522
Yu Haoyong,Ni Yan,Bao Yuqian,Zhang Pin,Zhao Aihua,Chen Ttianlu,Xie Guoxiang,Tu Yinfang,Zhang Lei,Su Mingming,Wei Li,Jia Wei* （通讯作者）,Jia Weiping* Chenodeoxycholic Acid as a Potential Prognostic Marker for Roux-en-Y Gastric Bypass in Chinese Obese Patients the Journal of Clinical Endocrinology & Metabolism 2015 100(11):4222-4230
Zhou Kejun,Xie Guoxiang,Wang Jun,Zhao Aihua,Liu Jiajian,Su Mingming,Ni Yi,Zhou Ying,Pan Weihua,Che Yanran,Zhang Ting,Xiao Yongtao,Wang Yang,Wen Jie,Jia Wei* （通讯作者）,Cai Wei* Metabonomics Reveals Metabolite Changes in Biliary Atresia Infants Journal of Proteome Research 2015 14(6):2569-2574
Chen Wenlian, Wang Jinghan, Zhao Aihua, Xu Xin, Wang Yihuang, Chen Tianlu, li Junmin, Mi Jianqing, Zhu Yongmei , Liu Yuanfang, Wang Yueying, Jin Jie, Huang He, Wu Depei, Li Yan, Yan Xiaojing, Yan Jinsong, Li Jianyong, Wang Shuai, Huang Xiaojun, Wang Bingshun, Chen Zhu, Chen Saijuan*, Jia Wei* （通讯作者） A distinct glucose metabolism signature of acute myeloid leukemia with prognostic value Blood 2014 124(10):1645-1654
Xie Guoxiang, Ma Xiaojing, Zhao Aihua, Wang Congrong, Zhang Yinan, David Nieman,Jeremy K. Nicholson, Jia Wei* （通讯作者）, Bao Yuqian*, Jia Weiping The Metabolite Profiles of the Obese Population are Gender-Dependent Journal of Proteome Research 2014 13(9):4062?4073
Xie Guoxiang, Lu Lingeng, Qiu Yunping, Ni Quanxing, Zhang Wei, Gao Yutang, Risch Harvey A., Yu Herbert*, Jia Wei* （通讯作者） Plasma Metabolite Biomarkers for the Detection of Pancreatic Cancer Journal of Proteome Research 2014 14(2):1195-1202
Qiu Yunping, Cai Guoxiang, Zhou Bingsen, Li Dan, Zhao Aihua, Xie Guoxiang, Li Houkai, cai Sanjun, Xie Dong, Huang Changzhi, Ge Weiting, Zhou Zhanxiang, Xu Lisa X, Jia Weiping, Zheng Shu, Yen Yun, Jia Wei* （通讯作者） A distinct metabolic signature of human colorectal cancer with prognostic potential Clinical Cancer Research 2014 20(8):2136-2146
Ni Yan, Xie Guoxiang, Jia Wei* （通讯作者） Metabonomics of Human Colorectal Cancer: New Approaches for Early Diagnosis and Biomarker Discovery Journal of Proteome Research 2014 13(9):3857-3870
Xie Guoxiang, Zhang Shucha, Zheng Xiaojiao, Jia Wei* （通讯作者） Metabolomics Approaches for Characterizing Metabolic Interactions Between Host and its Commensal Microbes Electrophoresis 2013 34(19):2787-2798
Zhong Wei, Li Qiong, Xie Guoxiang, Sun Xiuhua, Tan Xiaobing, Sun Xinguo, Jia Wei, Zhou Zhanxiang* Dietary fat sources differentially modulate intestinal barrier and hepatic inflammation in alcohol-induced liver injury in rats American Journal of Physiology-Gastrointestinal and Liver Physiology 2013 305(12):G919-G932
Xie Guoxiang, Zhong Wei, Zheng Xiaojiao, Li Qiong, Qiu Yunping, Li Houkai, Chen Huiyuan, Zhou Zhanxiang*, Jia Wei* （通讯作者） Chronic ethanol consumption alters mammalian gastrointestinal content metabolites Journal of Proteome Research 2013 12 (7):3297–3306
Qiu Yunping, Zhou Bingsen, Su Mingming, Baxter Sarah, Zheng Xiaojiao, Zhao Xueqing, Yen, Jia Wei* （通讯作者） Mass Spectrometry-based Quantitative Metabolomics Revealed a Distinct Lipid Profile in Breast Cancer Patients International Journal of Molecular Sciences 2013 14(4):8047-8061
Yang Jinlei, Chen Tianlu, Sun Liya, Zhao Z.M., Qi Xin, Cao Yu, Wang Xiaoyan, Qiu Yunping, Su Mingming, Zhao Aihua, Wang Pen, Yang Pan, Wu Jieli, Feng Guya, He Lin, Jia Wei* （通讯作者）, Wan Chuling* Potential Metabolite Markers of Schizophrenia Molecular Psychiatry 2013 18:67–78
Zheng Xiaojiao, Xie Guoxiang, Jia Wei* （通讯作者） Metabolomic Profiling in Colorectal Cancer: Opportunities for Personalized Medicine Personalized Medicine 2013 10(7):741-755
Xie Guoxiang, Li Xin, Li Houkai, Jia Wei* （通讯作者） Toward Personalized Nutrition: Comprehensive Phytoprofiling and Metabotyping Journal of Proteome Research 2013 12(4):1547-1559
Zheng Xiaojiao, Zhao Aihua*, Xie Guoxiang,Chi Yi,Zhao Linjing,Li Houkai, Wang Congrong, Bao Yuqian, Jia Weiping, Luther Mike, Su Mingming, Nicholson Jeremy K., Jia Wei* （通讯作者） Melamine-induced renal toxicity is mediated by the gut microbiota Science Translational Medicine 2013 5(172):172ra22
Wang Jinghan, Chen Wenlian, Li Junmin, Wu Songfang, Chen Tianlu, Zhu Yongmei, Zhang Weina, Li Yang, Qiu Yunping, Zhao Aihua, Mi Jianqing, Jin Jie, Wang Yungui, Ma Qiuling , Huang He, Wu Depei, Wang Qinrong, Li Yan, Yan Xiaojing, Yan Jinsong, Li Jianyong, Wang Shuai, Huang Xiaojun, Wang Bingshun, Jia Wei* （通讯作者）, Shen Yang*, Chen Zhu*, Chen Saijuan* Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China Proceedings of the National Academy of Sciences USA 2013 110(42):17017-17022
Houkai Li, Wei Jia* （通讯作者） Co-metabolism of microbes and host: implications for drug metabolism and drug-induced toxicity Clinical Pharmacology & Therapeutics 2013 94(5):574-581
Xie Guoxiang, Zhong Wei, Li Houkai, Li Qiong, Qiu Yunping , Zheng Xiaojiao, Chen Huiyuan, Zhao Xueqing, Zhang Shucha , Zhou Zhanxiang*, Zeise Steven H, Jia Wei* （通讯作者） Alteration of bile acid metabolism in the rat induced by chronic ethanol consumption The Journal of the Federation of American Societies for Experimental Biology 2013 27(9):3583-3593
Zheng Xiaojiao, Qiu Yunping, Zhong Wei, Baxter Sarah, Su Mingming, Li Qiong, Xie Guoxiang, Ore Brandon M., Qiao Shanlei,Spencer Melanie D., Zeisel Steven H.,Zhou Zhanxiang, Zhao Aihua*,Jia Wei* （通讯作者） A targeted metabolomic protocol for short-chain fatty acids and branched-chain amino acids Metabolomics 2013 9(4):818-827
Li Houkai, Zhou Yalu, Zhao Aihua, Qiu Yunping, Xie Guoxiang, Jiang Qi, Zheng Xiaojiao, Zhong Wen, Sun Xinghua, Zhou Zhanxiang, Jia Wei* （通讯作者） Asymmetric Dimethylarginine Attenuates Serum Starvation-Induced Apoptosis via Suppression of the Fas (APO-1/CD95)/JNK (SAPK) Pathway Cell Death and Disease 2013 e830-e830
Qi Ying, Li Pan, Zhang Yongyu, Cui Lulu, Guo Zi, Xie Guoxiang, Su Mingming, Li Xin, Zheng Xiaojiao, Qiu Yunping, Liu Yumin,Zhao Aihua, Jia Weiping, Jia Wei* （通讯作者） Urinary metabolite markers of precocious puberty. Urinary metabolite markers of precocious puberty Molecular & Cellular Proteomics 2012 11(1):M111.011072
Zhou Mingmei, Wang Shidong, Zhao Aihua, Wang Ke, Fan Ziquan, Yang Hongzhou, Liao Wen, Bao Si, Zhao Linjing, Zhang Yinan, Yang Yongqing, Qiu Yunping, Xie Guoxiang, Li Houkai*, Jia Wei* （通讯作者） Transcriptomic and metabonomic profiling reveal synergistic effects of quercetin and resveratrol supplementation in high fat diet fed mice Journal of Proteome Research 2012 11(10):4961-4971
Cheng Yu, Guo XiangXie, Chen Tianlu, Qiu Yunping, Zou Xia, Zheng Minhua, Tan Binbin, Feng Bo, Dong Taotao, He Pingang, Zhao Linjing, Zhao Aihua,Xu Lisa, Zhang Yan, Jia Wei* （通讯作者） Distinct Urinary Metabolic Profile of Human Colorectal Cancer Journal of proteome Research 2012 11(2):1354–1363
Yao Chun, Tang Nong, Xie Guoxiang, Zheng Xiaojiao, Liu Ping, Fu Lei, Xie Wu, Yao Fan, Li Houkai, Jia Wei* （通讯作者） Management of hepatic encephalopathy by traditional Chinese medicine Evidence-based Complementary and Alternative Medicine 2012 835686
Xie Guoxiang, Zhao Aihua Zhao Linjing, Chen Tianlu, Chen Huiyuan, Qi Xin, Zheng Xiaojiao, Ni Yan, Cheng Yu, Lan Ke, Yao Chun, Qiu Mingfeng, Jia Wei* Metabolic Fate of Tea Polyphenols in Humans Journal of Proteome Research 2012 11(6):3449-3457
Tan Xiaobing, Sun Xiuhua, Li Qiong, Zhao Yantao, Zhong Wei, Sun Xinguo, Jia Wei, McClain Craig J, Zhou Zhanxiang * Leptin deficiency contributes to the pathogenesis of alcoholic fatty liver disease in mice American Journal of Pathology 2012 181(4):1279-1286
Nicholson Jeremy K*, Holmes Elaine, Kinross James, Burcelin Remy, Gibson Glenn, Jia Wei, Pettersson Sven Host-gut microbiota metabolic interactions Science 2012 336(6086):1262-1267
Wang Xiaoning, Wang Xiaoyan, Xie Guoxiang, Zhou Mingmei, Yu Huan, Lin Yan, Du Guangli, Luo Guoan, Jia Wei* （通讯作者）, Liu Ping* Urinary metabolite variation is associated with pathological progression of the post-hepatitis B cirrhosis patients Journal of Proteome Research 2012 11(7):3838-3847
Ni Yan, Qiu Yunping, Jiang Wenxin, Suttlemyre Kyle, Su Mingming, Zhang Wenchao, Jia Wei* （通讯作者）, Du Xiuxia ADAP-GC 2.0: Deconvolution of Coeluting Metabolites from GC/TOF-MS Data for Metabolomics Studies Analytical Chemistry 2012 84(15):6619-6629
Holmes Elaine, Kinross James, Gibson Glenn R, Burcelin Remy, Jia Wei, Pettersson Sven, Nicholson Jeremy K* Therapeutic modulation of microbiota-host metabolic interactions Science Translational Medicine 2012 4(137):137rv6
Lu Jingyi, Zhou Jian, Bao Yuqian, Chen Tianlu, Zhang Yinan, Zhao Aihua, Qiu Yunping, Xie Guoxiang, Wang Congrong, Jia Wei* （通讯作者）, Jia Weiping* Serum metabolic signatures of fulminant type 1 diabetes Journal of Proteome Research 2012 11(9):4705-4711
Wang Tingting, Cai Guoxiang, Qiu Yunping, Fei Na, Zhang Menghui, Pang Xiaoyan, Jia Wei, Cai Sanjun, Zhao Liping* Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers The Journal of International Society for Microbial Ecology 2012 6(2):320-329
Chen Tianlu, Xie Guoxiang, Wang Xiaoying, Fan Jia, Qiu Yunping, Zheng Xiaojiao, Qi Xin, Cao Yu, Su Mingming, Wang Xiaoyan, Xu Lisa X, Yen Yun, Liu Ping, Jia Wei* （通讯作者） Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma Molecular & Cellular Proteomics 2011 10(7):M110.004945
Hua Yingqi, Qiu Yunping, Zhao Aihua, Wang Xiaoyan, Chen Tianlu, Zhang Zhiyu, Chi Yi, Li Quan, Sun Wei, Li Guodong, Cai Zhengdong, Zhou Zhanxiang, Jia Wei* （通讯作者） Dynamic Metabolic Transformation in Tumor Invasion and Metastasis in Mice with LM-8 Osteosarcoma Cell Transplantation Journal of Proteome Research 2011 10(8):3513–352
Zheng Xiaojiao, Xie Guoxiang, Zhao Aihua, Zhao Linjing, Yao Chun, Chiu Norman H L, Zhou Zhanxiang, Bao Yuqian, Jia Weiping*, NicholsonbJeremy K, Jia Wei* （通讯作者） The footprints of gut microbial-mammalian co-metabolism Journal of Proteome Research 2011 10(12):5512-5522
Sha Wei, Costa Kerry-Ann da, Fischer Leslie M, Michael V Lawton Milburn Kay A, Berger Alvin, Jia Wei, Zeisel Steven H* Metabolomics profiling can predict which humans will develop liver dysfunction when deprived of dietary choline The Journal of the Federation of American Societies for Experimental Biology 2010 24(8):2962-2975
Jia Wei* （通讯作者）, Zhao Liping, Nicholson Jeremy K. Gut microbiota: a potential new territory for drug targeting Nature Reviews Drug Discovery 2008 7:123-129