导师姓名： 汪年松 专业代码： 100201
性别： 男 专业名称： 内科学
培养单位： 附属第六人民医院 三级学科/
专业领域： 肾病
导师类型： 博士生导师 专业学位导师： 兼
联系方式： -58379
邮编： 200233 邮箱地址： wangniansong2012@163.com

研究方向 (点击浏览详细信息)
AKI的发病机制和防治；慢性肾脏病合并心血管并发症的机制和防治；糖尿病肾病发病机制与防治

社会任职
中华医学会肾脏病分会全国委员、上海医学会肾脏病分会候任主任委员、中国中西医结合肾病学会常委、中国医师学会肾脏病分会常委、华东肾脏病协作组委员、 上海市中西医结合肾病学会常委、上海市肾脏病临床康复委员会副主委、上海交通大学肾脏病学博士生和博士后导师、苏州大学肾脏病学博士生导师、上海中医药大学硕士生导师，中华肾脏病杂志、上海医学、中国中西医结合肾病杂志等统计源期刊编委

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
2019SY018 腹膜透析随访管理模式在基层医院的推广与应用 上海市卫计委 2019-09~2022-09 30万元 课题负责人
** Renalase通过调控PMCA4b/calcineurin/NFAT信号通路抑制慢性肾脏病心肌重构的分子机制研究 国家自然科学基金面上项目 2019-01~2023-01 57万元 课题负责人
2018-12 糖尿病肾病发病新机制和防治 上海市领军人才计划 2018-12~2022-12 160万元 课题负责人
** CD146参与Wnt5a/JNK信号通路及其对糖尿病肾病足细胞损伤和上皮间充质转变现象的作用机制研究 国家自然基金面上项目 2017-01~2021-02 58万元 课题负责人
暂无 基于microRNAs差异表达谱的糖尿病肾病早期诊断生物标志物临床应用研究 上海交大转化医学课题 2016-01~2018-12 10万元 课题负责人
** renalase对慢性肾脏疾病患者心血管事件的预测价值及renalase替代治疗慢肾衰的实验研究 国家自然基金面上项目 2013-01~2016-12 70万元 课题负责人
YB130913 基于ACGME能力模型对八年一贯制学生教学效果评价的比较研究 上海交通大学医学院医学教育研究课题 2012-01~2014-12 1.6万元 课题负责人
11DZ** 健脾清化法治疗脾虚湿热型慢性肾衰临床多中心大样本前瞻性研究 上海市科委 2011-07~2014-06 10万元 子课题负责人
11DZ** 高通量血透与常规血透联合血液透析滤过的临床疗效评价 上海市教委 2011-07~2013-06 10万元 子课题负责人
MicroRNA靶向GSK3beta参与糖尿病肾病系膜细胞肥大的机制研究 上海市国际科技合作基金项目 2011-07~2014-06 25万元 课题负责人
114119a6100 renalase高亲和力单抗的筛选与检测技术的建立 上海市科委 2011-01~2013-06 10万元 课题负责人
11DJ** 痛风和高尿酸血症发生机制与干预策略 上海市科委基础研究重大项目 2011-01~2013-12 10万元 子课题负责人
SHDC** 中西医结合治疗重症IGA肾病规范化方案的研究 上海市市级医院新兴前沿技术 ~ 10万元 子课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Xie L, Zhai R, Chen T, Gao C, Xue R, Wang N, Wang J, Xu Y, Gui D Panax Notoginseng Ameliorates Podocyte EMT by Targeting the Wnt/β-Catenin Signaling Pathway in STZ-Induced Diabetic Rats Drug Des Devel Ther 2020 14:527-538
Wen Y, Zhan X, Wang N, Peng F, Feng X, Wu X Monocyte/Lymphocyte Ratio and Cardiovascular Disease Mortality in Peritoneal Dialysis Patients Mediators Inflamm 2020 14;2020:**
Feng X, Wen Y, Peng FF, Wang N, Zhan X, Wu X Association between aminotransferase/alanine aminotransferase ratio and cardiovascular disease mortality in patients on peritoneal dialysis: a multi-center retrospective study BMC Nephrol 2020 21(1):209
Wang Y,Zhou T,Zhang Q,Fei Y,Li Z,Li S,He L,Zhang Q,Dong Y,Fan Y,Wang N. （通讯作者） Patients with Biopsy-Proven Diabetic Nephropathy Kidney Blood Press Res 2020 45(3):378-390
Xue R, Zhai R, Xie L, Zheng Z, Jian G, Chen T, Su J, Gao C, Wang N, Yang X, Xu Y, Gui D. Xuesaitong Protects Podocytes from Apoptosis in Diabetic Rats through Modulating PTEN-PDK1-Akt-mTOR Pathway J Diabetes Res 2020 **
Dong Y, Zhang Q, Wen J, Chen T, He L, Wang Y, Yin J, Wu R, Xue R, Li S, Fan Y, Wang N （通讯作者） Ischemic Duration and Frequency Determines AKI-to-CKD Progression Monitored by Dynamic Changes of Tubular Biomarkers in IRI Mice Front Physiol 2019 10:153
Zhang W, Mei C, Chen N, Ding X, Ni Z, Hao C, Zhang J, Zhang J, Wang N, Jiang G, Guo Z, Yu C, Deng Y, Li H, Yao Q, Marshall MR, Wolley MJ, Qian J Outcomes and practice patterns with hemodiafiltration in Shanghai: a longitudinal cohort study BMC Nephrol 2019 1;20(1):34
Zhai R, Jian G, Chen T, Xie L, Xue R, Gao C, Wang N （通讯作者）, Xu Y, Gui D Astragalus membranaceus and Panax notoginseng, the Novel Renoprotective Compound, Synergistically Protect against Podocyte Injury in Streptozotocin-Induced Diabetic Rats J Diabetes Res 2019 16;2019:**
Fan Y,Yi Z,D'Agati VD,Sun Z,Zhong F,Zhang W,Wen J,Zhou T,Li Z,He L, Zhang Q,Lee K,He JC,Wang N. （通讯作者） Comparison of Kidney Transcriptomic Profiles of Early and Advanced Diabetic Nephropathy Reveals Potential New Mechanisms for Disease Progression Diabetes 2019 68(12):2301-2314
Sheng X, Yang J, Yu G, Fei Y, Bao H, Yin J, Huang W, Tian Z, Wang N （通讯作者）, Ronco C. Procalcitonin and N-Terminal Pro-B-Type Natriuretic Peptide for Prognosis in Septic Acute Kidney Injury Patients Receiving Renal Replacement Therapy Blood Purif 2019 16:1-10
Liu P, Huang S, Ling S, Xu S, Wang F, Zhang W, Zhou R, He L, Xia X, Yao Z, Fan Y, Wang N, Hu C, Zhao X, Tucker HO, Wang J, Guo X Foxp1 controls brown/beige adipocyte differentiation and thermogenesis through regulating β3-AR desensitization Nat Commun 2019 10(1):5070.
Wu R, Liu X, Yin J, Wu H, Cai X, Wang N （通讯作者）, Qian Y, Wang F. IL-6 receptor blockade ameliorates diabetic nephropathy via inhibiting inflammasome in mice. Metabolism 2018 83:18-24.
Fan Y, Fei Y, Zheng L, Wang J, Xiao W, Wen J, Xu Y, Wang Y, He L, Guan J, Wei J, He JC, Wang N. （通讯作者） Expression of Endothelial Cell Injury Marker Cd146 Correlates with Disease Severity and Predicts the Renal Outcomes in Patients with Diabetic Nephropathy Cell Physiol Biochem 2018 48(1):63-74
Liang R, Zhao Q, Jian G, Cheng D, Wang N, Zhang G, Wang F. Tanshinone IIA Attenuates Contrast-Induced Nephropathy via Nrf2 Activation in Rats. Cell Physiol Biochem 2018 46(6):2616-2623.
Zhang R, Zhuang L, Li M, Zhang J, Zhao W, Ge X, Chen Y, Wang F, Wang N, Bao Y, Liu L, Liu Y, Jia W. Arg913Gln of SLC12A3 gene promotes development and progression of end-stage renal disease in Chinese type 2 diabetes mellitus. Mol Cell Biochem 2018 437(1-2):203-210
Li J, Li Y, Sheng X, Wang F, Cheng D, Jian G, Li Y, Feng L, Wang N. （通讯作者） Combination of Mean Platelet Volume/Platelet Count Ratio and the APACHE II Score Better Predicts the Short-Term Outcome in Patients with Acute Kidney Injury Receiving Continuous Renal Replacement Therapy. Kidney Blood Press Res 2018 43(2):479-489.
Wu R, Kong Y, Yin J, Liang R, Lu Z, Wang N, Zhao Q, Zhou Y, Yan C, Wang F, Liang M. Antithrombin Ⅲ is a Novel Predictor for Contrast Induced Nephropathy After Coronary Angiography. Kidney Blood Press Res 2018 43(1):170-180
Wu Y, Zhang G, Wang N, Xue Q. Risk Factors of Renal Involvement Based on Different Manifestations in Patients with Ankylosing Spondylitis Kidney Blood Press Res 2018 43(2):367-377
Li J, Sheng X, Cheng D, Wang F, Jian G, Li Y, Xu T, Wang X, Fan Y, Wang N. （通讯作者） Is the mean platelet volume a predictive marker of a high in-hospital mortality of acute cardiorenal syndrome patients receiving continuous renal replacement therapy? Medicine (Baltimore). 2018 97(25):e11180.
Yin J, Wang F, Kong Y, Wu R, Zhang G, Wang N, Wang L, Lu Z, Liang M. Antithrombin III prevents progression of chronic kidney disease following experimental ischaemic-reperfusion injury J Cell Mol Med. 2017 Aug 2. doi: 10.1111/jcmm.13261. [Epub ahead of print]
Rui Xue, Dingkun Gui, Liyang Zheng, Ruonan Zhai, Feng Wang, * and Niansong Wang * Mechanistic Insight and Management of Diabetic Nephropathy: Recent Progress and Future Perspective J Diabetes Res. 2017 2017: **.
He L, Fan Y, Xiao W, Chen T, Wen J, Dong Y, Wang Y, Li S, Xue R, Zheng L, He JC, Wang N （通讯作者） Febuxostat attenuates ER stress mediated kidney injury in a rat model of hyperuricemic nephropathy. Oncotarget 2017 8(67):111295-111308
Fan Y, Lee K, Wang N, He JC The Role of Endoplasmic Reticulum Stress in Diabetic Nephropathy. Curr Diab Rep. 2017 17(3):17.
Kong Y, Yin J, Cheng D, Lu Z, Wang N, Wang F, Liang M Antithrombin III Attenuates AKI Following Acute Severe Pancreatitis Shock. 2017 Jul 17. doi: 10.1097/SHK.0946. [Epub ahead of print]
Zeng C, Cheng D, Sheng X, Jian G, Fan Y, Chen Y, Li J, Bao H, Wang N （通讯作者） Increased Serum Uric Acid Level Is a Risk Factor for Left Ventricular Hypertrophy but Not Independent of eGFR in Patients with Type 2 Diabetic Kidney Disease J Diabetes Res. 2017 Epub 2017 Jun 20.
Chen X, Wu R, Kong Y, Yang Y, Gao Y, Sun D, Liu Q, Dai D, Lu Z, Wang N, Ge S, Wang F Tanshinone IIA attenuates renal damage in STZ-induced diabetic rats via inhibiting oxidative stress and inflammation Oncotarget. 2017 9;8(19):31915-31922.
Fan Y, Xiao W, Lee K, Salem F, Wen J, He L, Zhang J, Fei Y, Cheng D, Bao H, Liu Y, Lin F, Jiang G, Guo Z, Wang N （通讯作者）, He JC. Inhibition of Reticulon-1A-Mediated Endoplasmic Reticulum Stress in Early AKI Attenuates Renal Fibrosis Development. J Am Soc Nephrol. 2017 28(7):2007-2021
Fan Y, Zhang J, Xiao W, Lee K, Li Z, Wen J, He L, Gui D, Xue R, Jian G, Sheng X, He JC, Wang N. （通讯作者） Rtn1a-Mediated Endoplasmic Reticulum Stress in Podocyte Injury and Diabetic Nephropathy Sci Rep. 2017 2017; 7: 323.
Yin J, Chen W, Ma F, Lu Z, Wu R, Zhang G, Wang N, Wang F. Sulodexide pretreatment attenuates renal ischemia-reperfusion injury in rats Oncotarget. 2017 8(6): 9986–9995.
Jiang Z,Liu Y,Niu X, Yin J,Hu B,Guo S,Fan Y,Wang Y （通讯作者）,Wang N. Exosomes secreted by human urine-derived stem cells could prevent kidney complications from type I diabetes in rats Stem Cell Research & Therapy 2016 7:24
Zhang J, Fan Y, Zeng C, He L, Wang N （通讯作者） Tauroursodeoxycholic Acid Attenuates Renal Tubular Injury in a Mouse Model of Type 2 Diabetes Nutrients 2016 8(10):E589
Wang F, Peng C, Zhang G, Zhao Q, Xuan C, Wei M, Wang N （通讯作者） Delayed kidney injury following coronary angiography Exp Ther Med 2016 12(1):530-534
Wang F, Yin J, Lu Z, Zhang G, Li J, Xing T, Zhuang S, Wang N Limb ischemic preconditioning protects against contrast-induced nephropathy via renalase EBioMedicine. 2016 9:356-65
Huang B, Cheng Y, Usa K, Liu Y, Baker MA, Mattson DL, He Y, Wang N （通讯作者）, Liang M. Renal Tumor Necrosis Factor α Contributes to Hypertension in Dahl Salt-Sensitive Rats. Sci Rep 2016 26;6:21960
Wenzhen Xiao, Ying Fan, Niansong Wang, Peter Y. Chuang, Kyung Lee, John Cijiang He Knockdown of RTN1A attenuates ER stress and kidney injury in albumin overload-induced nephropathy American Journal of Physiology - Renal Physiology 2016 310(5):F409-15
Yin J, Lu Z, Wang F, Jiang Z, Lu L, Miao N, Wang N （通讯作者） Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy. J Cell Mol Med 2016 20(6):1106-17
Xiaoxia Wang,E Shen,Yanzhe Wang,Zhenzhen Jiang,Dingkun Gui,Dongsheng Cheng,Tingfang Chen,Niansong Wang （通讯作者） MiR-196a Regulates High Glucose-Induced Mesangial Cell Hypertrophy by Targeting p27(kip1) JALA 2015 02/2015; 20(4)
Fan Y, Li X, Xiao W, Fu J, Harris RC, Lindenmeyer M, Cohen CD, Guillot N, Baron MH, Wang N, Lee K, He JC, Schlondorff D, Chuang PY BAMBI elimination enhances alternative TGF-β signaling and glomerular dysfunction in diabetic mice Diabetes. 2015 64(6):2220-33
F Wang,J Li,T Xing,Y Xie,N Wang （通讯作者） Serum renalase is related to catecholamine levels and renal function Clin Exp Nephrol 2015 19:92-98
Wang F, Zhang G, Xing T, Lu Z, Li J, Peng C, Liu G, Wang N Renalase contributes to the renal protection of delayed ischaemic preconditioning via the regulation of hypoxia-inducible factor-1α JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 2015 19(6):1400-9
Yu-mei Liu, Hong-da Bao, Zhen-zhen Jiang, Ya-juan Huang, Nian-song Wang （通讯作者） Pregnancy-related Acute Kidney Injury and a Review of the Literature in China INTERNAL MEDICINE 2015 15;54(14):1695-703
Fan Y, Xiao W, Li Z, Li X, Chuang PY, Jim B, Zhang W, Wei C, Wang N, Jia W, Xiong H, Lee K, He JC RTN1 mediates progression of kidney disease by inducing ER stress NATURE COMMUNICATIONS 2015 31;6:7841
Guo Y,Jiang Q,Gui D,Wang N （通讯作者） Chinese Herbal Formulas Si-Wu-Tang and Er-Miao-San Synergistically Ameliorated Hyperuricemia and RenalImpairment in Rats Induced by Adenine and Potassium Oxonate Cell Physiol Biochem 2015 37:1491-1502
Chen T, Zheng LY, Xiao W, Gui D, Wang X, Wang N. （通讯作者） Emodin ameliorates high glucose induced-podocyte epithelial-mesenchymal transition in-vitro and in-vivo Cell Physiol Biochem 2015 35(4):1425-36
Wang F,Zhang G, Lu Z, Geurts AM, Usa K, Jacob HJ, Cowley AW, Wang N, Liang M Antithrombin III/SerpinC1 insufficiency exacerbates renal ischemia/reperfusion injury KIDNEY INTERNATIONAL 2015 88(4):796-803
Gui D,Wei L,Jian G,Guo Y,Yang J,Wang N （通讯作者） Notoginsenoside R1 Ameliorates Podocyte Adhesion Under Diabetic Condition Through α3β1 Integrin Upregulation in Vitro and in Vivo Cell Physiol Biochem 2014 34:1849-1862
Feng Wang, Liping Li, Haiming Xu, Yong Liu, Chun Yang, Allen W. Cowley Jr., Niansong Wang （通讯作者）, Pengyuan Liu,Mingyu Liang Characteristics of Long Non-coding RNAs in the Brown Norway Rat and Alterations in the Dahl Salt-Sensitive Rat Scientific reports 2014 Scientific Reports 4, Article number: 7146
Fan Y, Wang N, Chuang P, He JC. Role of HIPK2 in kidney fibrosis Kidney Int Suppl 2014 ;4(1):97-101
Yifang Chen,Dingkun Gui,Jianguo Chen,Dongyuan He,Yunling Luo,Niansong Wang （通讯作者） Down-regulation of PERK-ATF4-CHOP pathway by Astragaloside IV is associated with the inhibition of endoplasmic reticulum stress-induced podocyte apoptosis in diabetic rats Cell Physiol Biochem 2014 33(6):1975-1987
Cheng D, Fei Y, Liu Y, Li J, Xue Q, Wang X, Wang N （通讯作者） HbA1C variability and the risk of renal status progression in Diabetes Mellitus: a meta-analysis PLoS One 2014 Dec 18;9(12):e115509
Wang F, Huang B, Li J, Liu L, Wang N （通讯作者） Renalase might be associated with hypertension and insulin resistance in Type 2 diabetes. Ren Fail 2014 36(4):552-6
W Feng,X Tao,L Junhui,Z ZhiGang,W Niansong （通讯作者） Coexisting glomerular IgA deposition and IgG-kappa multiple myeloma. Ren Fail 2014 36(8):1345-1347
Cheng D, Fei Y, Liu Y, Li J, Chen Y, Wang X, Wang N （通讯作者） Efficacy and safety of dipeptidyl peptidase-4 inhibitors in type 2 diabetes mellitus patients with moderate to severe renal impairment: a systematic review and meta-analysis Plos One 2014 9(10):e111543
Tan S, Wang G, Guo Y, Gui D, Wang N （通讯作者） Preventive Effects of a Natural Anti-Inflammatory Agent, Astragaloside IV, on Ischemic Acute Kidney Injury in Rats Evid Based Complement Alternat Med 2013 284025-284025
Feng Wang,Junhui Li,Baorui Huang,Qing Zhao,Gang Yu,Changyou Xuan,Meng Wei,Niansong Wang （通讯作者） Clinical survey on contrast-induced nephropathy after coronary angiography Renal failure 2013 35(9):1255-1259
Wang F, Xing T, Li J, He Y, Bai M, Wang N （通讯作者） Survey on hospital-acquired urinary tract infection in neurological intensive care unit APMIS 2013 121(3):197-201
Gui D, Huang J, Guo Y, Chen J, Chen Y, Xiao W, Liu X, Wang N （通讯作者） Astragaloside IV ameliorates renal injury in streptozotocin-induced diabetic rats through inhibiting NF-κB-mediated inflammatory genes expression. Cytokine. 2013 61(3):970-7
Li J, Wang F, Jian G, Ma N, Fan Y, Yu G, Xue Q, Gao X, Wang N （通讯作者） Analysis of 24-hour ambulatory blood pressure monitoring in patients with diabetic nephropathy: a hospital-based study Clin Nephrol 2013 79(3):199-205
Gui D, Huang J, Liu W, Guo Y, Xiao W, Wang N （通讯作者） Astragaloside IV prevents acute kidney injury in two rodent models by inhibiting oxidative stress and apoptosis pathways Apoptosis 2013 18(4):409-22
Wang F, Xing T, Wang N （通讯作者）, Liu L Clinical significance of plasma CD146 and P-selectin in patients with type 2 diabetic nephropathy Cytokine 2012 57(1):127-129.
Gui D, Guo Y, Wang F, Liu W, Chen J, Chen Y, Huang J, Wang N （通讯作者） Astragaloside IV, a novel antioxidant, prevents glucose-induced podocyte apoptosis in vitro and in vivo PLoS One 2012 7(6):e39824
Yu Qiang Chen,Qing Xue,? Nian Song Wang. （通讯作者） Visceral muscle dysmotility syndrome in systemic lupus erythematosus: case report and review of the literature Rheumatol Int 2012 32(6):1701-1703
Wang F, Xing T, Li J, Bai M, Hu R, Zhao Z, Tian S, Zhang Z, Wang N （通讯作者） Renalase's Expression and Distribution in Renal Tissue and Cells PLoS One 2012 7(10):e46442
WANG Feng, ZHOU Yang , LI Jun-hui, GUI Ding-kun,LU Shi, YAO Yuan-zhang, LIU Li-mei, SHENG Xiao-hua,PENG Wen, WANG Nian-song （通讯作者） Survey on Arteriovenous Fistula in Maintenance Hemodialysis Patients with Type 2 Diabetic Nephropathy JSJU 2012 17(12):1-4
Yu Q. Chen, Xiao X. Wang, Xing M. Yao,Dong L. Zhang, Xu F. Yang, Shou F. Tian,Nian S. （通讯作者） Abated microRNA-195 expression protected mesangial cells from apoptosis in early diabetic renal injury in mice J Nephrol 2012 25(04):566-576
Yu Qiang Chen ,Yuan Wang,Feng Wang,? Nian Song Wang （通讯作者） Proteus Takayasu’s arteritis with unusual intracranial granulomatosis as initial manifestation. Rheumatol Int 2012 25(04):566-576.
Feng Wang, Mei Bai, Niansong Wang （通讯作者） Leflunomide therapy-associated tuberculosis infection AJMR 2012 6(9):1884-1886.
WANG Feng), CHENG Dong-sheng, WANG Nian-song.LI Wen-hui （通讯作者）, BAO Yu-qianb,ZHOU Jian, JIA Wei-ping Continuous Glucose Monitoring in the Patients with Diabetic Nephropathy JSJU 2011 16(4):508-512
Wang F, Xing T, Wang N （通讯作者）, Huang YJ A Clinical Study of Pregnancy Associated Renal Insufficiency Kidney Blood Press Res 2011 34(1):34-40
Yu Q. Chen, Xiao X. Wang, Xing M. Yao,Dong L. Zhang, Xu F. Yang, Shou F. Tian,Nian S. Wang （通讯作者） MicroRNA-195 Promotes Apoptosis in Mouse Podocytes via Enhanced Caspase Activity Driven by BCL2 Insufficiency. AJN 2011 34(6):549-559.
Yu Qiang Chen, Nian Song Wang （通讯作者）,Xiaohua Sheng,Xiaoguang Zhang,Yan Yan, Gang Yu, Yongping Cui, Lingquan Tang Hepatitis C virus infection in uremic patients on maintenance hemodialysis: A follow up study for 150 months AJMR 2011 5(22):3677-3683
Wang F, Bai M, Zhao B, Wang N （通讯作者） Voriconazole therapy: associated acute kidney injury AJMR 2011 5(22):4359-4362
WANG Feng,ZHAO Bing-hui,WANG Nian-song （通讯作者） Significance of Sacroiliac Joint Aerocele in Diagnosis of Ankylosing Spondylitis, JSJU 2011 16(5):636-640
Feng Wang, Nian-song Wang （通讯作者）, Tao Xing Construction of eukaryotic recombinant vector of renalase and its expression as a eukaryotic protein. J Shanghai Jiaotong Univer (EI) 2010 15(5):637-640
Wang Feng,Wang Niansong （通讯作者）,Li Junhui Analysis on the infection among patients with nephrotic syndromes and systemic vasculitis treated with mycophenolate mofetil. Clin Rheumatol 2010 29(9):1073-1074
Wang N （通讯作者）, Fan Y, Ni P, Wang F, Gao X, Xue Q, Tang L High glucose effect on the role of CD146 in human proximal tubular epithelial cells in vitro J Nephrol 2009 21(6):931-940