摘要/Abstract

N-取代-1，2，3-三氮唑是一类重要的含氮杂环化合物，在药物化学、合成化学及材料等领域都具有广泛的应用价值.因此，N-取代-1，2，3-三氮唑的构建方法备受人们的关注.归纳总结了近年来N-取代-1，2，3-三氮唑的合成研究进展，主要介绍了以叠氮化合物、腙、TsNHNH₂和重氮为氮源以及NH-1，2，3-三氮唑为前体合成N-取代-1，2，3-三氮唑化合物的合成路线及其反应机理，并对该领域未来的发展进行了展望.
关键词: N-取代-1,2,3-三氮唑, 叠氮化合物, 腙, TsNHNH₂, 重氮, NH-1,2,3-三氮唑
N-Substituted-1,2,3-triazoles are an important class of nitrogen-containing hetrocyclic compounds, which exhibited wide applications in various fields such as medicinal chemistry, synthetic chemistry and materials. Therefore, their synthetic methods have attracted great attention of chemists. Herein, the recent research progress in the synthesis of N-substituted-1,2,3-triazoles is summarized. The synthetic routes and reaction mechanisms from raw materials such as azide compounds, diazo compounds, TsNHNH₂, hydrazones and NH-1,2,3-triazoles are introduced and reviewed, respectively. Finally, the future development of this field is also prospected.
Key words: N-substituted-1,2,3-triazole, azide compound, hydrazone, TsNHNH₂, diazo compound, NH-1,2,3-triazole


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