摘要/Abstract

总结了近年来过渡金属催化的不对称电化学进展.过渡金属催化的不对称电化学（AOMCE）分为氧化和还原反应.在氧化反应方面，发展了烯烃的不对称官能团化，二级醇或醛的动力学拆分以及碳氢键的不对称官能团化反应.在还原反应部分包括二氧化碳的不对称电化学羧化、不对称电化学脱羧反应以及不对称还原偶联反应.手性配体和过渡金属催化剂与电化学体系的结合构成了一个非常新颖的反应体系，为解决传统有机电化学合成中立体选择性控制的难题，提供了一条新途径.
关键词: 过渡金属催化的不对称电化学, 有机电化学合成, 不对称催化
The recent developments in asymmetric organotransition metal-catalyzed electrochemistry (AOMCE) are summarized. AOMCE processes can be divided into oxidative and reductive variants. In terms of oxidations, asymmetric functionalization of olefins, oxidative kinetic resolution of secondary alcohols or aldehydes, and asymmetric C—H functionalization reactions have been developed. Reductive processes discussed include asymmetric electrochemical carboxylation with carbon dioxide, asymmetric electrochemical decarboxylation, and asymmetric reductive coupling reactions. The combination of chiral ligands, transition-metal catalysts, and electrochemistry provides a novel angle by which to address the longstanding fundamental challenge of stereoinduction in traditional electrochemical organic synthesis.
Key words: asymmetric organotransition metal-catalyzed electrochemistry, electrochemical organic synthesis, asymmetric catalysis


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