摘要/Abstract

胺类化合物是一类重要的合成中间体，亚胺的氢硅化反应为胺类化合物的合成提供了一种便利的方法.过渡金属及主族元素催化剂在亚胺氢硅化反应中得到了广泛应用，然而，采用更加简单的反应条件实现这类反应更加具有实用价值.利用廉价易得的叔丁醇钾作为促进剂，实现了醛亚胺的快速还原反应，以良好的收率高效合成了一系列胺类化合物.该反应体系具有反应迅速，条件简单，实用高效的优点.
关键词: 氢硅化反应, 醛亚胺, 快速反应, 碱催化
Amines are important intermediates in organic synthesis. The hydrosilylation of imines provides a convenient method for the synthesis of amines. Transition metal and main group catalysts have been widely applied in the hydrosilylation of imines. However, it would be more practical to use simpler reaction conditions to realize such reactions. In this paper, a fast hydrosilylation of aldimine was realized by using cheap t-BuOK as the promoter, providing an efficient method for the synthesis of amines in high yield. This reaction features rapid reaction, facile conditions, and robust practicability.
Key words: hydrosilylation, aldimine, rapid reaction, base catalysis


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