摘要/Abstract

报道了一种N-碘代丁二酰亚胺（NIS）/K₂S₂O₈促进的烯酰胺自偶联反应构建C—C键的方法.这种无过渡金属催化的自由基反应具有环境友好和原子经济性高的显著优势，为合成含氮原子的季碳中心结构骨架提供了一种实用方法.
关键词: 季碳中心骨架, 烯酰胺, C—C键构建, 碘化物, 自由基加成, 无过渡金属
N-Iodo-succininide (NIS)/K₂S₂O₈ initiated C-C bond formation reaction through self-coupling of enamides has been reported. The environmental friendliness and high atom-economy of this transition-metal free radical pathway offers a useful and attractive strategy to nitrogen-containing quaternary carbon centers.
Key words: quaternary carbon centers, enamides, C-C bond formation, iodide, radical addition, transition-metal free


PDF全文下载地址:

点我下载PDF