摘要/Abstract

硫酸有效地催化炔丙醇和一系列碳和氧亲核试剂的直接亲核取代反应以形成碳-碳键和碳-氧键.反应可以在未除水溶剂中和空气条件下进行并获得良好的产率.室温下大多数底物的反应能在1 min内完成.
关键词: 硫酸, 催化, 炔丙醇, 亲核取代
Sulfuric acid efficiently catalyzes the direct substitution of the hydroxyl group of propargylic alcohols with a variety of C- and O-based nucleophiles to aid C-C and C-O bond formation. The reactions can be performed in an undried solvent under air atmosphere to obtain the desired products in good yields. In most cases, the reaction proceeds to completion in 1 min at room temperature.
Key words: sulfuric acid, catalyzed, propargyl alcohols, nucleophilic substitution


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