摘要/Abstract

C—N键广泛存在于药物分子、天然产物及功能材料中，开发简洁高效的C—N键构建方法具有重要意义.近年来，无过渡金属体系下C（sp²）—H键的自由基反应构建C—N键取得了诸多进展.该方法反应条件相对温和，反应活性较高，为C—N键构建提供了一条新途径.根据氮源类型的不同，对近年来C（sp²）—H键的自由基反应构建C—N键的研究进展进行简要论述.
关键词: C—N键, C (sp²)—H键, 无过渡金属, 自由基
The C-N bond is widely found in medicinal molecules, natural products and functional materials. Therefore, it has great significance to develop simple and efficient methods for the construction of C-N bond. Recently, remarkable progress has been made in construction of C-N bond involving C(sp²)-H bond through transition-metal-free radical reactions. Due to the relatively mild reaction condition and high reactivity, it provides a novel approach to construct C-N bond. In this review, the recent developments in this area are summarized on the basis of different nitrogen sources.
Key words: C—N bond, C (sp²)—H bond, transition-metal-free, radical


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