摘要/Abstract

发展了一种银催化高效高区域选择性的2-芳基吲哚C-3位烷基化反应.在温和条件下，能以高达97%的收率得到目标化合物，且该方法操作简单，不需要外加氧化剂.
关键词: 银催化, 2-芳基吲哚, 马来酰亚胺, 烷基化
A highly efficient and regioselective C-3-alkylation of 2-arylindoles with maleimides has been developed using Ag(I) as catalyst. 3-(2-Aryl-1H-indol-3-yl)pyrrolidine-2,5-diones were afforded with high yields (up to 97%) under relatively mild reaction conditions. The method features operational simplicity and avoiding external oxidant.
Key words: silver-catalyzed, 2-arylindoles, maleimides, alkylation


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