摘要/Abstract

在温和的反应条件下，使用ZnAl-XO₃^--LDHs（X=Br，I）为氧化剂和相应的金属卤化物LiX为还原剂，实现烯烃的二溴化及碘乙酰氧基化反应，合成一系列二溴烷烃和碘乙酸酯类产物.分析结果表明，该方法产率较高，二溴烷烃类为74%~94%，碘乙酸酯类为75%~93%，该反应具有高区域选择性和立体选择性.
关键词: 烯烃, 二溴化, 碘乙酰氧基化, 区域选择性, 立体选择性
This study describes efficient vicinal dibromination and iodoacetoxylation of olefins under mild reaction conditions. The reaction uses ZnAl-XO₃^--layered double hydroxide (LDHs) (X=Br or I) as an oxidant and LiX as a reductant to generate halogens in situ (ZnAl-XO₃^--LDH/LiX system). A series of dibromoalkanes (74%~95%) and iodoacetates (75%~93%) were obtained in good to excellent yields with high regio-and stereo-selectivity.
Key words: olefins, dibromination, iodoacetoxylation, regioselectivity, stereoselectivity


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