摘要/Abstract
通过研究发现[Rh（COD）Cl]2/ZnI2/（2R，4R）-（+）-2，4-bis（diphenylphosphino）pentane作为共催化体系，能有效地催化酚类亲核试剂对氧杂苯并降冰片烯的不对称亲核开环反应，获得较好的收率和良好的对映选择性.在优化后的反应条件下，该共催化体系具有良好的催化活性和底物适应能力，能够实现各种取代的酚类亲核试剂对氧杂苯并降冰片烯的不对称开环，高效而又经济地合成不同取代的含手性四氢萘结构单元的化合物.
关键词: 铑, 氧杂苯并降冰片烯, 共催化, 不对称开环反应, 路易斯酸
The complex of[Rh(COD) Cl]2 and 2R,4R) -(+) -2,4-bis(diphenylphosphino) pentane was used as an effective catalyst for the asymmetric ring opening reaction of oxabenzonorbornadienes with various phenols by employing ZnI2 as the activator. Under the optimized reaction conditions, high enantioselectivities with good yields could be obtained from a wide scope of oxabenzonorbornadienes and phenols.
Key words: rhodium, oxabenzonorbornadienes, Co-catalysis, symmetric ring opening reaction, Lewis acid
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