摘要/Abstract
分别以D-半乳糖、L-阿拉伯糖为原料完成了叠氮鞘氨醇的合成，总收率分别为27%和20%.此策略主要特征是烯烃复分解反应、自由基诱导的异构化、Appel反应和叠氮取代.
关键词: 鞘氨醇, 合成, 糖, 烯烃复分解, 取代
Synthesis of azidosphingosine has been described from D-galactose and L-arabinose with an overall yields of 27% an 20%, respectively. Our strategy features olefin cross-metathesis reaction, radical-induced isomerization, appel reaction, and azido replacement.
Key words: sphingosine, synthesis, carbohydrate, olefin cross-metathesis, replacement
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