摘要/Abstract

利用介孔分子筛MCM-41固载磷钨酸作为非均相催化剂，在水相中，简单高效地催化亚胺和丙二腈进行亲核加成-消去反应，合成了一系列的苄烯丙二腈化合物，产率最高可达99%.该方法具有操作简单、环境友好、底物普适性好、产率高和催化剂可回收再利用等优点，为碳-碳键的构筑提供了一种新的方法.
关键词: MCM-41, 磷钨酸, 加成-消去反应, 非均相催化剂
A convenient and excellent yield procedure for the preparation of benzylidenemalononitrile by addition-elimination reaction of imine with malonitrile in the presence of immobilized H₃PW₁₂O₄₀ as heterogeneous catalyst in water is described, and a variety of the corresponding products were obtained in high yield (up to 99%). The approach was characterized by simple operation, environment friendly, excellent yields and the catalyst was found to exhibit better recyclability. It provides a new method for the carbon-carbon bond formation in organic synthesis.
Key words: MCM-41, phosphoric acid, addition-elimination reaction, heterogeneous catalyst


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