摘要/Abstract

无碱条件下，二甲基亚砜（DMSO）为溶剂，利用氧化亚铜在空气气氛中催化端基炔偶联，高效合成1，3-丁二炔类化合物，并研究了其反应机理.另外，该体系可放大至克级规模反应，且催化剂氧化亚铜可以回收利用.
关键词: 氧化亚铜, 偶联, 端基炔, 无碱
A high efficient method for the synthesis of 1,3-diynes derivatives which employed terminal alkynes as the substrates and copper(I) oxide as the catalyst was developed. This method possessed the character of base-free and mild reaction conditions. The reaction mechanism was also studied. Furthermore, this reaction could be magnified to gram scale and the catalyst of copper(I) oxide could be recycled.
Key words: copper (I) oxide, homocoupling, terminal alkynes, base-free


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