姓名：张志鸿
出生年月：1940年1月
职称：教授、博导
电话：(86-21) 65643673, 65643924, 65642810
FAX: (86-21) 65650149
E-mail: zhzhang@fudan.edu.cn



简历：1963年毕业于复旦大学生物物理学专业；1979-1981年日本京都大学访问学者；1988年获日本京都大学理学博士学位；1990-1991年美国哈佛医学院高级访问学者；1991年至今为复旦大学生命科学学院生理学和生物物理学系教授；1994-2002年任中国生物物理学会副理事长；1996-2000年任复旦大学生命科学学院副院长；2000年至今为上海生物物理学会理事长


主要研究方向：
二十多年来一直从事生物膜研究，特别是物质跨膜转运、膜蛋白结构和功能的课题。目前课题组主要的研究方向是：(1)红细胞膜上带3蛋白和葡萄糖转运蛋白的转运特性，生物膜上蛋白质相互作用对物质转运的调控； (2) 生物膜上离子通道特性，特别是机械敏感性离子通道功能的调控机理；(3) 膜蛋白的结构生物学，目前主要研究带3蛋白胞质段与带4.2间的相互作用；(4) 用蛋白质组学技术研究糖尿病患者红细胞膜蛋白质组的异常；（5）失神经肌肉萎缩的蛋白质组学研究。


代表性著作和论文：
1. 张志鸿，刘文龙 (1987), “膜生物物理学”, 高等教育出版社。
2. Zhi-hong Zhang and A.K.Solomon (1992), Effect of pCMBS on Anion Transport in Human Red Cell Membrane Biochim. Biophys. Acta 1106:31-39.
3. Zhou Han-qing and Zhang Zhi-hong (1994), The Measurement of Anion Permeability by Hemolytic Kinetics of the Red Cells, Chin. J. Biochem. Biophys. 26:119-126.
4. Peng Feng and Zhang Zhihong (1996), Effect of DIDS on the Function of Glucose Transport Protein in Red Cell Membranes, Chin. Sci. Bull. 40:68-72.
5. Minqin Chen, Changchuan Yin, Wei Zhang, Yumin Mao, and Zhihong Zhang (1998), Purification, Crystallization and Preliminary X-Ray Diffraction Studies on the Thermostable Catechol 2,3-dioxygenase of Bacillus stearothermophilus Expressed in Escherichia coli Acta Crystallgraphica D54:446-447.
6. Xiao-jian Hu, Feng Peng, Han-qing Zhou, Zhi-hong Zhang, Wei-ying Cheng and Hang-fang Feng (2000), The Abnormality of Glucose Transporter in the Erythrocyte Membrane of Chinese Type 2 Diabetic Patients, Biochim. Biophys. Acta 1466: 306-314.
7. Y.A.Mei, M.M..Wu, C.L.Huan, J.T.Sun, H.Q.Zhou, Z.H.Zhang (2000), 4-Aminopyridine, a Specific Bloker of K+ Channels, Inhibited Inward Na+ Current in Rat Cerebellar Granule Cells, Brain Res. 873:46-53.
8. Wei Hua, Mei Yan-Ai, Wu Ming-ming, Sun Jia-ting, Zhou Han-qing, Zhang Zhi-hong
(2000), Swelling-activated chloride currents in embryonic chick heart cells,
Acta Pharmacol Sin 21(11): 986-990.
9. Y.A.Mei, P.P.N.Lee, H.Wei, Z.H.Zhang and S.F.Peng (2001), Melatonin and its analogs
potentiate the nifedipine-sensitive high-voltage-activated calcium current in the chick
embryonic heart cells, J. Pineal Res 30:13-21.
10. 张志鸿 (2001), 新世纪推动生物科学发展的“Bio-X”, 生物物理学报 17(1):1-9.
11. TANG Lin, SUN Qing"an, LI Qingguo, HUANG Yibo, WEI Qingqing, ZHANG Yi,
HU Jun, ZHANG Zhihong, LI Minqian & YANG Fujia (2001),
imaging bacteriorhodopsin-like molecules of claret-membranes from Tibet
halobacteria xz515 by atomic force microscope, Chinese Science Bulletin 46(22):
1897-1900.
12. Li Y-Z, Zhou H-Q, Peng F and Zhang Z-H (2001), Effect on glucose transport and
anion exchange in human erythrocytes by mechanical force factors,
Acta Biochim. Biophys. Sinica 33(5):489-496.
13. HUAN Chun-lei, ZHOU Mi-ou, WU Ming-ming, ZHANG Zhi-hong, MEI Yan-ai
(2001), Activation of melatonin receptor increases a delayed retifier K+ current in rat
cerebellar granule cells, Brain Research 917: 182-190.
14. JIANG Weihua, DING Yu, HU Xiaojian, PENG Feng, ZHOU Hanqing & ZHANG Zhihong (2002), Effect on membrane transport in the erythrocytes by band 3 cross-linking, Chinese Science Bulletin 47(22): 1889-1892.
15. Hua WEI, Yan Ai MEI, Jia Ting SUN, Han Qing ZHOU, Zhi Hong Zhang (2003), Regulation of swelling-activated chloride channels in embryonic chick heart cells, Cell Research 13 (1): 21-28.
16. Ming Jiang, Linzhi Jia, Weihua Jiang, Xiaojian Hu, Hanqing Zhou, Xin Gao, Zhiqiang Lu, and Zhihong Zhang (2003), Protein disregulation in red blood cell membranes of type 2 diabetic patients, Biochem. Biophys. Res. Commun. 309: 196-200.
17. Yu Ding, Weihua Jiang, Yang Su, Hanqing Zhou, and Zhihong Zhang (2004), Expression and purification of recombinant cytoplasmic domain of human erythrocyte band 3 with hexahistridine tag or chitin-binding tag in Escherichia coli., Protein Express. Purif. 34:167-175.
18. Linzhi Jia, Lei Xu, Ming Jiang, Yudong Gu, and Zhihong Zhang (2005), Protein abnormality in denervated skelatal muscles from patients with brachial injury, Microsurgery (in press).
19. Yu Ding, Ming Jiang, Weihua Jiang, Yang Su, Hanqing Zhou, Xiaojian Hu, and Zhihong Zhang (2005), Expression, purification, and characterization of recombinant human flotillin-1 in Escherichia coli . Protein Express. Purif. (in press).
20．张志鸿，"同步辐射应用概论"（马礼敦，杨福家主编，2001年第一版，2005年第二版），第十二章 "同步辐射在生命科学中的应用"，复旦大学出版社。
21 张志鸿 (2005),"生物膜"（杨福愉主编） 第七章 "生物膜蛋白质组学"，科学出版社。