陈杰 详细介绍
性别 男
职称 教授
最高学历 博士
毕业院校 南京农业大学
专业领域 动物分子遗传与育种
联系方式 jiechen@njau.edu.cn
研究方向 畜禽重要经济性状形成的分子机制；畜禽分子育种技术
参加学术团体
及任职情况 中国畜牧兽医学会动物遗传育种学分会 理事中国畜牧兽医学会动物遗传标记学分会 理事
承担项目 ? 猪肌内前体脂肪细胞分化特异性调控基因的分离与功能研究，国家自然科学基金青年科学基金项目，**，2009.01-2011.12? P160 基因家族组织特异性调控猪肌内脂肪沉积的分子机制研究，国家自然科学基金，**，2013.01-2016.12? 鹅产蛋性能分子选育技术研究及应用于扬州鹅高产蛋品系选育研究，江苏省农业科技自主创新资金，CX(14)2071，2014.07-2017.06? 高产优质转基因奶羊新品种培育，农业部转基因生物新品种培育重大专项，2011ZX08008-004，2011.07-2012.12? 基于全基因组关联分析挖掘猪肌内脂肪含量相关基因的研究，中央高校基本科研业务费专项资金项目，KYZ201113，2011.5-2014.4
奖励及荣誉
论文论著

Fu Y, Sun W, Xu C, Gu S, Li Y, Liu Z, Chen J*. Genetic Variants in KDR Transcriptional Regulatory Region Affect Promoter Activity and Intramuscular Fat Deposition in Erhualian pigs. Animal Genetics, 2014 doi: 10.1111
Liu Z, Sun W, Zhao Y, Xu C, Fu Y, Li Y, Chen J*. The effect of variants in the promoter of BMPER on the intramuscular fat deposition in longissimus dorsi muscle of 3 pigs. Gene, 2014 doi: 10.1016
W Sun, Z Xie, S Zhang, W Nan, J Chen*. Identification of the porcine sialoadhesin gene promoter region and its cell-specific expression in porcine alveolar macrophage cells. Genet Mol Res, 2014 (in press)
Wu W, Ren Z, Li P, Yu D, Chen J, Huang R, Liu H. Six1: A critical transcription factor in tumorigenesis. Int J Cancer. 2014. doi: 10.1002
Xiong K, Li S, Zhang H, Cui Y, Yu D, Li Y, Sun W, Fu Y, Teng Y, Liu Z, Zhou X, Xiao P, Li J, Liu H, Chen J*. Targeted editing of goat genome with modular-assembly zinc finger nucleases based on activity prediction by computational molecular modeling. Mol Biol Rep. 2013, 40(7): 4251-6.
H. Wang, K. Xiong, W. Sun, Y. Fu, Z. Jiang, D. Yu, Honglin Liu, Jie Chen*. Two completely linked polymorphisms in the PPARG transcriptional regulatory region significantly affect gene expression and intramuscular fat deposition in the longissimus dorsi muscle of Erhualian pigs. Animal Genetics, 2013, 44(4): 458-62
Wenxing Sun, Huanhuan Wang, Yansen Li, Xiaolong Zhou, Yun Teng, Jie Chen*. Acquisition of pig intramuscular preadipocytes through dedifferentiation of mature adipocytes and establishment of optimal inducing condition. Genet Mol Res, 2013, 12(4):
Sun WX, Wang HH,.JiangBC, Zhao YY, Xie ZR, Xiong K, Chen J*. Global comparison of gene expression between subcutaneous and intramuscular adipose tissue of mature Erhualian pig. Genet Mol Res, 2013,12(4): 5085-5101
K Xiong, S Li, H Zhang, Y Cui, D Yu, X Zhou, W Sun, P Xiao, Y Fu, Y Teng, Q Xiong, H Fu, J Li, H Liu, J Chen. Goat genome editing with zinc-finger nucleases constructed via modular-assembly based on efficiency prediction of computer molecular modeling. Transgenic Res, 2013, 241
Wei S, Duarte MS, Zan L, Du M, Jiang Z, Guan LL, Chen J*, Hausman GJ, Dodson MV*. Celluar and Molecular Implications of Mature Adipocyte Dedifferentiation. J Genomics, 2012, 1: 5-12
Zhang S, Xiong K, Xie Z, Nan W, Liu H, Chen J*. Stable silencing of β-lactoglobulin (BLG) gene by lentivirus-mediated RNAi in goat fetal fibroblasts. Genet Mol Biol, 2012, 35(3): 680-685
Chen J, Dodson MV, Jiang Z*. Cellular and molecular comparison of redifferentiation of intramuscular- and visceral-adipocyte derived progeny cells. Int J Biol Sci., 2010, 6: 80-88
Wang X, Xue C, Wang X, Liu H, Xu Y, Zhao R, Jiang Z, Dodson MV, Chen J*. Differential display of expressed genes reveals a novel function of SFRS18 inregulation of intramuscular fat deposition. Int J Biol Sci., 2009, 5: 28-33
Chen J, Guridi M, Fernyhough ME, Jiang Z, Guan LL, Hausman GJ, Dodson MV. Clonal mature adipocyte production of proliferative-competent daughter cells requires lipid export prior to cell division. Int J Stem Cells, 2009, 2: 76-79
Chen J, Guridi M, Fernyhough M, Jiang Z, Guan LL, Hausman G, Dodson MV. Initial differences in lipid processing leading to pig- and beef- derived mature adipocyte dedifferentiation. Basic Applied Myology, 2009, 19: 243-46.
Wang X, Chen J*, Liu H, Xu Y, Wang X, Xue C, Yu D, Jiang Z. The pig p160 co-activator family: full length cDNA cloning, expression and effects on intramuscular fat content in Longissimus Dorsi muscle. Domest Anim Endocrinol., 2008, 35: 208-16
Chen J, Yang XJ, Xia D, Chen J, Wegner J, Jiang Z, Zhao RQ. SREBF1 expression and genetic polymorphism significantly affect intramuscular fat deposition in the longissimus muscle of Erhualian and Sutai pigs. J. Anim. Sci., 2008. 86: 57-63
Yang X, Chen J, Xu Q, Zhao R. Muscle type-specific responses of myoD and calpain 3 expression to recombinant porcine growth hormone in the pig. Animal, 2007. 1: 989-996
Jiang Z, Michal J, Chen J, Daniels T, Kunej T, Garcia M, Gaskins C, Busboom J, Alexander L, Wright R, Macneil M. Discovery of novel genetic networks associated with 19 economically important traits in beed cattel. Int J Biol Sci., 2009, 5: 528-42.
Dodson MV, Jiang Z, Chen J, et al. Allied industry approaches to alter intramuscular fat content and composition in beef animals. Journal of Food Science, 2010, 75: R1-R8.