万永杰 详细介绍
性别 男
职称 副教授
最高学历 博士
毕业院校 南京农业大学
专业领域 动物遗传育种与繁殖
联系方式 wanyongjie@njau.edu.cn
研究方向 动物胚胎工程；肉羊繁育
参加学术团体
及任职情况 中国畜牧兽医学会动物繁殖学分会、养羊学分会会员
承担项目 1.国家自然科学基金面上项目：m6A甲基化修饰参与调控山羊体细胞核移植胚胎母源-合子转换期重编程的研究（主持，2020-2023）2.国家自然科学基金（青年）：代谢谱与山羊克隆胚胎及其供体细胞发育潜能相关性研究（主持，2014-2016）3.中央高校基本科研业务费专项资金项目2项（主持，2014-2016、2018）4.国家自然科学基金项目（面上）：山羊早期卵泡和克隆胚胎发育中抗氧化机制的研究（参加，2013-2016）5.转基因生物新品种培育重大专项：高产优质转基因奶羊新品种培育（参加“乳铁蛋白转基因奶山羊新品种培育”任务，2008-2015）6.国家肉羊产业技术体系（参加，2016-2020）7.国家重点研发计划项目：山羊规模化高效安全养殖关键技术集成与示范（参加，2018-2020）8.国家科技支撑计划项目子任务：华南地区肉羊高效克隆胚胎生产与移植技术研究（参加，2011-2013）9.江苏省重点研发计划：优质肉用多胎绵羊新品系的选育及湖羊特色性状关键基因的挖掘（参加，2015-2018）
奖励及荣誉 1. 参加“基于“学研产”结合的动物繁殖学教学改革实践”，获2013年江苏省优秀教学成果二等奖；2. 参加“长三角区域肉羊规模化高效精准养殖关键技术集成与应用”，获农业部中华农业科技奖二等奖；
论文论著

Liu ZF, Zhang GM, Deng MT, Yang H, Pang J, Cai Y, Wan YJ*, Wang F*. Inhibition of lysine-specific histone demethylase 1A results in meiotic aberration during oocyte maturation in vitro in goats[J]. Theriogenology, 2020, 143: 168-178
Deng MT, Liu ZF, Chen BB, Cai Y, Wan YJ*, Wang F*. Locus-Specific Regulation of Xist Expression Using the CRISPR-Cas9-Based System[J]. DNA Cell Biol, 2020, 39(4): 572-578
Deng MT, Zhang GM, Cai Y, Liu ZF, Zhang YL, Meng F, Wang F, Wan YJ*. DNA methylation dynamics during zygotic genome activation in goat[J]. Theriogenology, 2020, 156: 144-154
Ma JY, Ren CF, Yang H, Zhao J, Wang F*, Wan YJ*. The Expression Pattern of p32 in Sheep Muscle and Its Role in Differentiation, Cell Proliferation, and Apoptosis of Myoblasts[J]. Int J Mol Sci, 2019, 20(20): 5156
Wan YJ, Guo RH, Deng MT, LiuZF, Pang J, Zhang GM, Wang ZY, Wang F*. Efficient generation of CLPG1-editedrabbits using the CRISPR/Cas9 system[J]. Reprod Domest Anim, 2019, 54(3):538-544
Deng MT, Liu ZF, Ren CF, An SY, Wan YJ*, Wang F*. Highly methylated Xist in SCNT embryos was retained in deceased cloned female goats[J]. Reprod Fertil Dev, 2019, 31: 855–866
Wan YJ, Zhang YL, Zhou ZR, Jia RX, Meng L, Hong S, Wang ZY, Wang LZ, Zhang GM, You JH, Wang F*. Efficiency of donor cell preparation and recipient oocyte source forproduction of transgenic cloned dairy goats harboring human lactoferrin [J]. Theriogenology. 2012; 78:583-92.
Wan YJ, Deng MT, Zhang GM, Ren CF, Zhang H, Zhang YL, Wang LZ, Wang F*. Abnormal expression of DNA methyltransferases and genomic imprinting in cloned goat fibroblasts [J]. Cell biology international. 2016;40:74-82.
Wan YJ, Deng MT, Zhang GM, Ren CF, Liu ZF, Wang F*. Analysis of H19/Igf2 Methylation Status in the Sperm of Cloned Goats and Their Offspring [J]. Cell Reprogram, 2018, 20(1): 66-75.
Guo RH#, Wan YJ#, Xu D, Cui LB, Deng MT, Zhang GM, Jia RX, Zhou WJ, Wang Z, Deng KP, Huang MR, Wang F*, Zhang YL*. Generation and evaluation of Myostatin knock-out rabbits and goats using CRISPR/Cas9 system [J]. Scientific Reports. 2016, 6: 29855.
Meng L#, Wan YJ#, Sun YY, Zhang YL, Wang ZY, Song Y, Wang F*. Generation of Five Human Lactoferrin Transgenic Cloned Goats Using Fibroblast Cells and Their Methylation Status of Putative Differential Methylation Regions of IGF2R and H19 Imprinted Genes [J]. PloS one. 2013;8:e77798.
万永杰, 肖慎华, 邓明田, 张国敏, 贾若欣, 张艳丽, 王锋, 黄明睿*. 胚龄、季节和胚胎数量对转人乳铁蛋白基因克隆奶山羊生产效率的影响[J]. 南京农业大学学报. 2015;38(6):980-985.
Deng MT, Liu ZF, Ren CF, Zhang GM, Pang J, Zhang YL, Wang F*, Wan YJ*. Long noncoding RNAs exchange during zygotic genome activation in goat [J]. Biol Reprod, 2018, 0(0):1–11.
Zhou ZZ, Jia RX, Zhang GM, Wan YJ*, Zhang YL, Fan YX, Wang ZY, Huang P, Wang F. Using cysteine/cystine to overcome oxidative stress in goat oocytes and embryos cultured in vitro [J]. Molecular Medicine Reports, 2016, 14(2): 1219-1226.
Zhang GM#, Wan YJ#, Zhang YL, Lan S, Jia RX, Wang ZY, Fan YX, Wang F*. Expression of Mitochondria-Associated Genes (PPARGC1A, NRF-1, BCL-2 and BAX) in Follicular Development and Atresia of Goat Ovaries [J]. Reproduction in domestic animals. 2015;50:465-473.
Deng MT, Ren CF, Liu ZF, Zhang GM, Wang F*, Wan YJ*. Epigenetic Status of H19-Igf2 Imprinted Genes and Loss of 5-Hydroxymethylcytosine in the Brain of Cloned Goats [J]. Cell Reprogram, 2017, 19(0): 1-9.
Nie HT#, Wan YJ#, You JH, Wang ZY, Lan S, Fan YX, Wang F*. Effect of Age on Energy Requirement for Maintenance and Growth of Dorper and Hu Crossbred F1 Ewes Weighing 20 to 50 kg [J]. Asian-Australas J Anim Sci. 2015;28:1140-9.