Dr Chiou Jiachi, Amber Assoc. DoRiFood & Assistant Professor

Location Y807
Phone +852 3400 8664
mail jiachi.amber.chiou@polyu.edu.hk

Open Platform for University Scholars
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Education and Academic Qualifications Doctor of Philosophy, Rutgers University
Master of Science, National Taiwan University
Bachelor of Science in Agriculture, National Taiwan University




Research Overview We are interested in the roles of probiotics and their metabolites in the microbial ecosystem as to affect health with focuses on metabolic disorders.




Academic and Professional Experiences Since 2016 Reviewer, Journal of Integrative Agriculture, Elsevier, China
Since 2016 Reviewer, Antimicrobial Agents and Chemotherapy
Member, Institute of Food Scientist (IFT)
Member, American Society for Microbiologist (ASM)




Research Interests
Bacterial Toxins
Enzymes
Probiotics



Achievements

Awards
2020 Faculty Award for Outstanding Achievement– Research and Scholarly Activities (Team Award)




Patents
Wong KY, Chan TH, Chan KF, Chen S, Lui HK, Kan J. WY, Chiou JC, Yap HK. 3-Amino Benzamide Derivative Serving As B-Lactam Auxiliary Antibiotic, Preparation Method and Use Thereof. Patent number: US2A1.
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HC Wu, YC T. Lam, TF Shum, TY Tsai, JC Chiou*. Hypotensive effect of captopril on deoxycorticosterone acetate-salt hypertensive rat by altering gut microbiota. In review
Wen-Yi Wang, Jia-Chi Chiou, Joanne Yip, Ka-Fu Yung and Chi-Wai Kan. Development of Durable Antibacterial Textile Fabrics for Potential Application in Healthcare Environment. Coatings 2020, 10 (6), 520.
AX Song, LQ Li, JY Yin, JC Chiou, JY Wu. Mechanistic insights into the structure-dependent and strain-specific utilization of wheat arabinoxylan by Bifidobacterium longum. Carbohydrate polymers 2020.
KL Lam,WY Cheng,F Yang,SL Lin,LJ You,JC Chiou,HS Kwan,Peter CK Cheung. Framework as a Service, FaaS: Personalized Prebiotic Development for Infants with the Elements of Time and Parametric Modelling ofin vitroFermentation. Microorganisms 2020, 8(5): 623.
WY Wang, JC Chiou, J Yip, KF Yung and CW Kan. Development of Durable Antibacterial Textile Fabrics for Potential Application in Healthcare Environment. Coatings 2020, 10 (6): 520.
Lui, HK, Gao W, Cheung KC, Jin WB, Sun N, Kan JWY, Wong ILK, Chiou J, Lin D, Chan EWC, Leung YC, Chan TH, Chen S, Chan KF, Wong KY. Boosting the efficacy of anti-MRSA β-lactam antibiotics via an easily accessible, non-cytotoxic and orally bioavailable FtsZ inhibitor. European J. Medicinal Chem 2019, 163: 95-115.
Liu TH, Chiou J, Tsai TY. (2016) Effects ofLactobacillus plantarumTWK10-fermented soymilk on deoxycorticosterone acetate-salt -induced hypertension and associated dementia in rats. Nutrients. 8(5). Pii: E260.
He, D., Chiou, J., Zeng, Z., Chan, E.W.-C., Liu, J.-H., Chen, S. (2016) Comparative characterization of CTX-M-64 and CTX-M-14 provides insights into the structure and catalytic activity of the CTX-M class of enzymes. Antimicrob Agents Chemother. 60(10): 6084-6090.
Li RC, Chiou JC, Chan WC, Chen S. A novel PCR-based approach for accurate identification ofVibrio parahaemolyticus. (2016) Frontier Microbiology 7:44doi: 10.3389/fmicb.2016.00044. eCollection 2016.
Chiou JC*, Leung HH*, Lee HW*, Wong WT. (2015) Rapid testing methods for food contaminants and toxicants (Review). J Integr Agr 14(11): 2243-2264. *contribute to the paper equally.
He DD*, Chiou JC*, Zeng ZL, Liu LP, Chen XJ, Zhen L, Chan WC, Liu JH, Chen S (2015). Residues distal to the active site contribute to enhanced catalytic activity of variant and hybrid β-lactamases derived from CTX-M-14 and -15. Antimicrob Agents Chemother. 59(10): 5976-5983. *contribute to the paper equally
Chiou JC, Wan SB, Chan KF, So PK, He DD, Chan WC, Chan TH, Wong KY, Tao J, Chen S (2015). Ebselen as a potent covalent inhibitor for New Delhi Metallo β-lactamases (NDM-1). Chem Commun (Camb). 51(46): 9543-9546.
Chiou JC, Li RC and Chen S (2015). CARB-17 family of β-lactamases mediated intrinsic resistance to penicillins in Vibrio parahaemolyticus. Antimicrob Agents Chemother. 59(6): 3593-3595.
Wang Y, Chan FY, Sun N, Lui HK, So PK, Yan SC, Chan KF,Chiou J, Chen S, Abagyan R, Leung YC, Wong KY (2014).Structure-based Design, Synthesis, and Biological Evaluation of Isatin Derivatives as Potential Glycosyltransferase Inhibitors.Chem Biol Drug Des. 84(6): 685-696. (Grade B: top 44% in Chemistry, Medicinal, IF: 2.485)
Chiou J, Leung TY, Chen S (2014). Molecular Mechanisms of Substrate Recognition and Specificity of New Delhi Metallo-β-Lactamase. Antimicrob Agents Chemother. 58(9): 5372-5378.
Chiou JC, Li XP, Remacha M, Ballesta JP, Tumer NE (2011).Shiga toxin1 is more dependent on the P proteins of the ribosomal stalk for depurination activity thanShiga toxin2.Int J Biochem Cell Biol. 43(12): 1792-1801.