Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 姚凯诗教授 (药剂学院) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1517/14656566.2011.521153 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/12WOS source URL
其它资讯
摘要Areas covered: Published studies on pharmacoeconomics of warfarin pharmacogenomic application are reviewed. A literature search was done using Medline and Embase covering the period 2000 -- 2010. Decision tree and Markov modeling were the most frequently used methods in the reviewed reports. Studies incorporating clinical efficacy data of genotype-guided dosing algorithm had shown that warfarin pharmacogenomics would improve quality-adjusted life-years (QALYs) gained. Nevertheless, it was unlikely to be cost-effective for general patients. Influential factors to improve the cost-effectiveness included low genotyping cost, high effectiveness in improving anticoagulation control/event rate, and applying warfarin pharmacogenomics to patients with high bleeding risk or at practice sites with suboptimal management of anticoagulation control.
着者You JHS
期刊名称EXPERT OPINION ON PHARMACOTHERAPY
出版年份2011
月份2
日期1
卷号http://aims.cuhk.edu.hk/converis/portal/Publication/12
期次3
出版社INFORMA HEALTHCARE
页次435 - 441
国际标準期刊号1465-6566
电子国际标準期刊号1744-7666
语言英式英语
Web of Science 学科类别Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY
