Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 汤宁信教授 |
| 李?前教授 (药剂学院) |
| 李咏恩教授 (药剂学院) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.3111/13696990801913950 |
引用次数
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/1Scopus source URL
其它资讯
摘要At the time of this study Tony HW Chan and Tina TL Ko were Master of Clinical Pharmacy degree candidates, School of Pharmacy, The Chinese University of Hong Kong. Objective: This study aimed to investigate the association between inadequately controlled hypertension, medication use pattern and the incidence of cardiovascular events (CVEs) over 5 years. The cost of hospitalisation associated with inadequately controlled hypertension was estimated. Methods: This was a retrospective observational study of patients who were diagnosed with hypertension with at least one blood pressure reading recorded at baseline (year 2000), reviewed from 200http://aims.cuhk.edu.hk/converis/portal/Publication/1-2005. Primary endpoints were the extent, duration and prevalence of blood pressure deviation from treatment goals. Secondary endpoints were incidence of CVEs and the number of days of hospitalisation associated with inadequately controlled hypertension. Results: In total, the medical records of 2http://aims.cuhk.edu.hk/converis/portal/Publication/10 patients were reviewed. Statistically significant positive associations were found between inadequately controlled systolic blood pressure with the incidence of CVEs (p=0.0http://aims.cuhk.edu.hk/converis/portal/Publication/18) and increased cardiovascular drugs (p<0.00http://aims.cuhk.edu.hk/converis/portal/Publication/1), non-cardiovascular drugs (p=0.0http://aims.cuhk.edu.hk/converis/portal/Publication/19) and total drug usage (p<0.00http://aims.cuhk.edu.hk/converis/portal/Publication/1). Similar observations were observed between inadequately controlled diastolic blood pressure and increased cardiovascular (p<0.05) and total (p=0.007) drug usage. Patients with uncontrolled blood pressure at all times during the study period were associated with a higher incidence of CVEs (p=0.026). The mean cost of hospitalisation due to CVEs was estimated to be HK$42,584.0 ± 36,670.0 (US$http://aims.cuhk.edu.hk/converis/portal/Publication/1 = HK$7.8) and it accounted for 3.3% of the total healthcare expenditure during 2005. Conclusion: Inadequately controlled blood pressure is positively associated with an increased incidence of CVEs and polypharmacy in Hong Kong Chinese hypertensive patients. ? 2008 Informa UK Ltd.
着者Lee V.W.Y., Chan T.H.W., Ko T.T.L., Lee K.K.C., Tomlinson B.
期刊名称Journal of Medical Economics (JME)
出版年份2008
月份5
日期7
卷号http://aims.cuhk.edu.hk/converis/portal/Publication/1http://aims.cuhk.edu.hk/converis/portal/Publication/1
期次http://aims.cuhk.edu.hk/converis/portal/Publication/1
出版社P J B Publications Ltd.
出版地United Kingdom
页次http://aims.cuhk.edu.hk/converis/portal/Publication/10http://aims.cuhk.edu.hk/converis/portal/Publication/1 - http://aims.cuhk.edu.hk/converis/portal/Publication/1http://aims.cuhk.edu.hk/converis/portal/Publication/18
国际标準期刊号http://aims.cuhk.edu.hk/converis/portal/Publication/1369-6998
语言英式英语
关键词Association, Cardiovascular events, Cost, Hypertension
