Publication in refereed journal
香港中文大学研究人员 ( 现职)
| 李国铭教授 |
| 李?前教授 (药剂学院) |
| 李咏恩教授 (药剂学院) |
| 谭丽珊教授 (内科及药物治疗学系) |
| 朱燕儿教授 (矫形外科及创伤学系) |
全文
| 数位物件识别号 (DOI) http://dx.doi.org/10.1093/rheumatology/ken287 |
引用次数
Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/28WOS source URL
Scopushttp://aims.cuhk.edu.hk/converis/portal/Publication/35Scopus source URL
其它资讯
摘要Objectives. To assess the annual direct, indirect and total societal costs, quality of life (QoL) of AS in a Chinese population in Hong Kong and determine the cost determinants. Methods. A retrospective, non-randomized, cross-sectional study was performed in a cohort of 145 patients with AS in Hong Kong. Participants completed questionnaires on sociodemographics, work status and out-of-pocket expenses. Health resources consumption was recorded by chart review. Functional impairment and disease activity were measured using the Bath Ankylosing Spondylitis Functional Index (BASFI) and the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), respectively. Patients' QoL was assessed using the Short Form-36 (SF-36). Results. The mean age of the patients was 40 yrs with mean disease duration of 10 yrs. The mean BASDAI score was 4.7 and BASFI score was 3.3. Annual total costs averaged USD 9120. Direct costs accounted for 38% of the total costs while indirect costs accounted for 62%. Costs of technical examinations represented the largest proportion of total cost. Patients with AS reported significantly impaired QoL. Functional impairment became the major cost driver of direct costs and total costs. Conclusion. There is a substantial societal cost related to the treatment of AS in Hong Kong. Functional impairment is the most important cost driver. Treatments that reduce functional impairment may be effective to decrease the costs of AS and improve the patient's QoL, and ease the pressure on the healthcare system. ? The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved.
着者Zhu T.Y., Tam L.-S., Lee V.W.-Y., Hwang W.W., Li T.K., Lee K.K., Li E.K.
期刊名称Rheumatology
出版年份2008
月份9
日期8
卷号47
期次9
出版社Oxford University Press
出版地United Kingdom
页次1422 - 1425
国际标準期刊号1462-0324
电子国际标準期刊号1462-0332
语言英式英语
关键词Ankylosing spondylitis, Cost of illness, Quality of life
