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Engineering of pharmaceutical materials: An industrial perspective (2008)_香港中文大学

香港中文大学 辅仁网/2017-06-27

Engineering of pharmaceutical materials: An industrial perspective
Publication in refereed journal


香港中文大学研究人员 ( 现职)
周喜林教授 (药剂学院)


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Web of Sciencehttp://aims.cuhk.edu.hk/converis/portal/Publication/53WOS source URL

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摘要Crystal engineering provides a rational approach to solving formulation, processing and product performance problems. This review discusses how the concept of crystal engineering can be judiciously utilized to manipulate the solid-state properties of drugs and excipients for successful pharmaceutical formulation and process development. Existing and emerging manufacturing as well as co-processing technologies being applied in the pharmaceutical industry are also presented together with selected examples of crystal form design, crystal form selection and crystal modifications for illustration purposes. (C) 2007 Wiley-Liss, Inc. and the American Pharmacists Association.

着者Chow K, Tong HHY, Lum S, Chow AHL
期刊名称JOURNAL OF PHARMACEUTICAL SCIENCES
出版年份2008
月份8
日期1
卷号97
期次8
出版社Elsevier
页次2855 - 2877
国际标準期刊号0022-3549
电子国际标準期刊号1520-6017
语言英式英语

关键词crystal engineering; crystallization; formulation; particle size; pharmaceutical manufacturing; polymorphism; preformulation; selection of salt forms
Web of Science 学科类别Chemistry; Chemistry, Medicinal; CHEMISTRY, MEDICINAL; Chemistry, Multidisciplinary; CHEMISTRY, MULTIDISCIPLINARY; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY

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