Use of recombinant activated factor VII after axillofemoral bypass grafting
Publication in refereed journal


香港中文大学研究人员 ( 现职)

何名熙教授 (麻醉及深切治疗学系)

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摘要Recombinant activated factor VII (rFVIIa) is a powerful prohaemostatic agent that theoretically predisposes to thrombosis after peripheral vascular surgery. We report the use of rFVIIa to reduce bleeding in a patient after axillofemoral bypass grafting for ruptured aorto-iliac pseudoaneurysm. Despite the increased risk of thrombosis, the patient made an uneventful recovery with preserved graft patency. The favourable result suggests that rFVIIa should be considered even in vascular surgical patients, if the risks of continued bleeding outweigh those of thrombosis. Better risk estimation is only possible if reports of rFVIIa use in vascular patients continue to appear and through controlled trials.

着者Cheng CAY, Ho AMH
期刊名称Anaesthesia and Intensive Care
出版年份2006
月份6
日期1
卷号3http://aims.cuhk.edu.hk/converis/portal/Publication/4
期次3
出版社AUSTRALIAN SOC ANAESTHETISTS
页次375 - 378
国际标準期刊号0310-057X
电子国际标準期刊号1http://aims.cuhk.edu.hk/converis/portal/Publication/4http://aims.cuhk.edu.hk/converis/portal/Publication/48-0271
语言英式英语

关键词abdominal compartment syndrome; atherosclerosis; haemorrhage; multiorgan failure; thrombosis
Web of Science 学科类别Anesthesiology; ANESTHESIOLOGY; Critical Care Medicine; CRITICAL CARE MEDICINE; General & Internal Medicine